4 free views remaining today
cobalt allergic contact dermatitis
ICD-10 Codes
Related ICD-10:
Description
Cobalt Allergic Contact Dermatitis: A Skin Reaction to Cobalt Exposure
Cobalt allergic contact dermatitis
Additional Characteristics
- Cobalt Allergic Contact Dermatitis
Signs and Symptoms
Common Signs and Symptoms of Cobalt Allergic Contact Dermatitis
Cobalt allergic contact dermatitis can manifest in various ways, making it essential to be aware of the common signs and symptoms. Here are some of the key indicators:
- Skin Rash or Hives: A red, itchy rash or hives on the skin can occur due to cobalt exposure [1].
- Difficulty Breathing or Chest Tightness: In severe cases, cobalt allergy can cause respiratory issues, such as difficulty breathing or chest tightness [2].
- Swelling and Redness at the Site of Contact: The affected area may experience swelling, redness, and inflammation due to the allergic reaction [3].
- Eczema or Dermatitis: Cobalt exposure can lead to eczematous reactions, which can be chronic or subacute in nature [4].
In severe cases, cobalt allergy can cause more pronounced symptoms, including:
- Blisters: Blisters may form on the skin due to the allergic reaction, and if they burst, the skin may "weep" (ooze a fluid) [5].
- Skin Pain and Tightness: The affected area may feel tight and painful, indicating a severe allergic reaction [6].
It's essential to note that cobalt poisoning can also occur through prolonged contact with the skin or swallowing large amounts of cobalt-containing substances. However, these symptoms are more related to cobalt poisoning rather than allergic contact dermatitis.
References:
[1] Context result 1 [2] Context result 2 [3] Context result 3 [4] Context result 6 [5] Context result 8 [6] Context result 8
Additional Symptoms
- Blisters
- Skin Rash or Hives
- Difficulty Breathing or Chest Tightness
- Swelling and Redness at the Site of Contact
- Skin Pain and Tightness
- eczema
Diagnostic Tests
Diagnosing Cobalt Allergic Contact Dermatitis
Cobalt allergic contact dermatitis can be challenging to diagnose, but several diagnostic tests are available to help identify the condition.
- Patch Testing: This is the primary method for diagnosing cobalt allergy. A small amount of cobalt chloride in aqueous solution (2%) is applied to the skin under adhesive patches, which are removed after 48 hours [6][7].
Additional Diagnostic Tests
- Patch Testing
Treatment
Treatment Options for Cobalt Allergic Contact Dermatitis
Cobalt allergy can be managed through a combination of avoidance and topical treatments.
- Avoidance: The most effective treatment for cobalt allergic contact dermatitis is to avoid all contact with sources of cobalt. This includes avoiding the use of certain products, such as jewelry or coins, that may contain cobalt.
- Topical Treatments: In addition to avoidance, topical corticosteroid creams can be applied to affected areas to reduce inflammation and itching. Emollients can also be used to soothe and moisturize the skin.
Specific Treatment Options
According to various sources [3][7], treatment of cobalt allergic contact dermatitis may include:
- Applying corticosteroid creams to affected areas
- Using emollients to soothe and moisturize the skin
- Avoiding all contact with sources of cobalt
It's worth noting that while these treatments can provide relief, they do not address the underlying allergy. In some cases, a small amount of cobalt may be applied to the skin under adhesive patches to test for an allergic reaction [4].
References
[1] Contact dermatitis treatment includes: Topical steroids · Emollients; Treatment of secondary bacterial infection. [3] A study of systemic nickel allergy found a dose-response relationship between nickel and symptoms, which resolved with a restriction of dietary nickel. [4] A small amount of cobalt is applied to the skin under adhesive patches, which are removed after 48 hours. Reaction site is checked for eczema or irritation. [7] Cobalt allergy can be managed by avoiding contact with cobalt-containing items, applying corticosteroid creams to affected areas, and taking symptomatic treatments.
Recommended Medications
- Topical corticosteroid creams
- Emollients
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnosis for Cobalt Allergic Contact Dermatitis
Cobalt allergic contact dermatitis can be challenging to diagnose, and a thorough differential diagnosis is essential to rule out other conditions that may present similarly. Here are some possible differential diagnoses:
- Allergic contact dermatitis to other metals: Other metals such as nickel, chromate, and zinc can cause similar skin reactions, making it essential to perform patch testing to confirm the presence of cobalt allergy [1].
- Discoid eczema: This is a type of eczema that presents with coin-shaped patches on the skin, which may be mistaken for allergic contact dermatitis. However, discoid eczema typically affects the face and scalp [2].
- Irritant contact dermatitis: Irritant contact dermatitis can cause similar symptoms to allergic contact dermatitis, including redness, itching, and blistering. However, it is usually caused by direct contact with a substance rather than an immune response [3].
Diagnostic Tests
To confirm the diagnosis of cobalt allergic contact dermatitis, the following tests may be performed:
- Epicutaneous patch testing: This involves applying small amounts of cobalt chloride to the skin and observing for a reaction. A positive result confirms the presence of cobalt allergy [4].
- Oral metal challenge: In some cases, an oral metal challenge with metals such as nickel, cobalt, chrome, and zinc may be performed to confirm the diagnosis of metal allergy [5].
References
[1] Yoshihisa Y. (2012). A diagnosis of sensitivity to metal is established by epicutaneous patch testing and oral metal challenge with metals such as nickel, cobalt, chromium, and zinc. [6] [2] Midander K. (2023). CoNPs potently elicit immune responses in Co-sensitized individuals. Even though patch testing with CoNPs resulted in a lower skin dose than CoCl2, identical elicitation responses were observed. [7] [3] Pesqué D. (Cited by 3). Contact dermatitis (CD) is a type of skin inflammatory reaction that occurs secondary to contact with a specific substance. [8] [4] Yoshihisa Y. (Cited by 179). Oral metal challenges with nickel, cobalt, chrome, and zinc are sometimes performed and are diagnostic for metal allergies, especially SCD. [5] [6] Midander K. (2023). In our study, we demonstrate that cobalt nanoparticles (CoNPs) have the potential to cause elicitation responses in cobalt sensitized individuals, manifest. [9] [7] Pesqué D. (Cited by 3). Contact dermatitis (CD) is a type of skin inflammatory reaction that occurs secondary to contact with a specific substance. [8] [8] Yoshihisa Y. (2012). A diagnosis of sensitivity to metal is established by epicutaneous patch testing and oral metal challenge with metals such as nickel, cobalt, chromium, and zinc. [6] [9] Midander K. (2023). In our study, we demonstrate that cobalt nanoparticles (CoNPs) have the potential to cause elicitation responses in cobalt sensitized individuals, manifest. [7]
Note: The references provided are based on the search results and may not be an exhaustive list of all relevant studies on this topic.
Additional Differential Diagnoses
- Irritant contact dermatitis
- Discoid eczema
- allergic contact dermatitis
Additional Information
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_54
- owl#annotatedSource
- t328405
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:0040053
- core#notation
- DOID:0040053
- oboInOwl#hasExactSynonym
- allergic contact dermatitis to Co
- IAO_0000115
- An allergic contact dermatitis that has_allergic_trigger cobalt atom.
- rdf-schema#label
- cobalt allergic contact dermatitis
- RO_0001022
- http://purl.obolibrary.org/obo/CHEBI_27638
- rdf-schema#subClassOf
- t328305
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/doid#DO_IEDB_slim
- relatedICD
- http://example.org/icd10/T24.531
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
Medical Disclaimer: The information provided on this website is for general informational and educational purposes only.
It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.