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obsolete Chryseobacterium indologenes pneumonia

ICD-10 Codes

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Description

Chryseobacterium indologenes Pneumonia: An Obsolete but Serious Infection

Chryseobacterium indologenes (C. indologenes) is a rare and opportunistic pathogen that can cause severe infections, including pneumonia. Although it was once considered an obsolete infection, C. indologenes remains a significant concern in healthcare settings.

Characteristics of the Pathogen

  • C. indologenes is a non-motile, Gram-negative rod that is widely distributed in nature.
  • It is commonly found in soil and water but can also be isolated from various sources in hospital settings.
  • The bacterium is known to be intrinsically multi-drug resistant, making treatment challenging.

Infection Types

C. indologenes pneumonia is a rare but serious infection that can occur in individuals with underlying immunosuppression or those who have been hospitalized for an extended period. Other types of infections caused by this pathogen include:

  • Bacteremia
  • Meningitis
  • Myositis
  • Keratitis
  • Indwelling device-associated infections

Risk Factors

Individuals with the following risk factors are more susceptible to C. indologenes pneumonia:

  • Congenital heart disease
  • Immunosuppression
  • Prolonged hospitalization
  • Use of invasive medical devices (e.g., ventilators, endotracheal tubes)

Treatment and Prevention

Due to its multi-drug resistance, treatment of C. indologenes pneumonia requires a comprehensive approach that includes:

  • Early detection and isolation of the pathogen
  • Appropriate antibiotic therapy
  • Supportive care for infected patients

Prevention strategies include:

  • Implementing strict infection control measures in healthcare settings
  • Monitoring patients with underlying immunosuppression or those who have been hospitalized for an extended period
  • Educating healthcare professionals about the risks and management of C. indologenes infections

Additional Characteristics

  • Chryseobacterium indologenes (C. indologenes) is a rare and opportunistic pathogen that can cause severe infections, including pneumonia.
  • C. indologenes is a non-motile, Gram-negative rod that is widely distributed in nature.
  • The bacterium is known to be intrinsically multi-drug resistant, making treatment challenging.
  • C. indologenes pneumonia is a rare but serious infection that can occur in individuals with underlying immunosuppression or those who have been hospitalized for an extended period.
  • Individuals with congenital heart disease are more susceptible to C. indologenes pneumonia.
  • Treatment of C. indologenes pneumonia requires a comprehensive approach that includes early detection and isolation of the pathogen, appropriate antibiotic therapy, and supportive care for infected patients.

Signs and Symptoms

Based on the provided context, it appears that there are limited resources available for information on Chryseobacterium indologenes pneumonia.

However, I can provide some general information on the topic. Chryseobacterium indologenes is a type of bacteria that can cause infections in humans, particularly in individuals with weakened immune systems or those who have had medical devices inserted into their bodies (e.g., ventilators).

According to search result [5], Chryseobacterium indologenes pneumonia is an uncommon pathogen of human disease. It has been associated with various conditions, including bacteremia, peritonitis, pneumonia, empyema, pyelonephritis, cystitis, meningitis, and central venous catheter-related bloodstream infections.

Regarding the signs and symptoms of Chryseobacterium indologenes pneumonia, it is mentioned in search result [3] that a patient developed signs and symptoms of Ventilator-Associated Pneumonia (VAP) on hospital day 5. The diagnosis was confirmed based on a quantitative culture from a respiratory sample.

Unfortunately, there is limited information available on the specific signs and symptoms of Chryseobacterium indologenes pneumonia in the provided context. However, it can be inferred that the condition may present with similar symptoms to other types of pneumonia, such as:

  • Respiratory distress
  • Shortness of breath (tachypnea)
  • Coughing
  • Chest pain or discomfort
  • Fever
  • Chills

Please note that these are general symptoms and not specific to Chryseobacterium indologenes pneumonia. If you have any further questions or would like more information, I'd be happy to try and assist you.

References: [3] - On hospital day 5, the patient developed signs and symptoms of VAP. A diagnosis of C indologenes VAP was confirmed based on a quantitative culture from a respiratory sample. [5] - Abstract: Chryseobacterium indologenes is an uncommon pathogen of human disease and is usually associated with indwelling devices or immunocompromised hosts

Additional Symptoms

Diagnostic Tests

Diagnostic Tests for Obsolete Chryseobacterium indologenes Pneumonia

Chryseobacterium indologenes is a bacterium that was previously known as Flavobacterium. It is a rare cause of pneumonia, and its diagnosis can be challenging. Here are some diagnostic tests that may be used to diagnose obsolete Chryseobacterium indologenes pneumonia:

  • Quantitative culture: This test involves taking a sample from the patient's respiratory tract and culturing it in a laboratory to identify the presence of C. indologenes [6].
  • Blood cultures: Blood cultures can also be performed to detect the presence of C. indologenes in the bloodstream [1].
  • Cerebrospinal fluid (CSF) culture: In cases where the pneumonia has spread to the brain, a CSF culture may be performed to diagnose meningitis [2][3].
  • Antimicrobial susceptibility testing: This test is used to determine which antibiotics are effective against C. indologenes [4][5].

It's worth noting that Chryseobacterium indologenes is no longer considered a valid species, and it has been reclassified as part of the genus Chryseobacterium. However, the diagnostic tests mentioned above may still be relevant for diagnosing infections caused by this bacterium.

References:

[1] Bhagawati, G. (2019). Multidrug-resistant E. coli infection in a patient with ventilator-associated pneumonia. [Context result 1]

[2][3] Calderón, G. (2011). Empiric antibiotic therapy for ventilator-associated pneumonia caused by Chryseobacterium indologenes. [Context results 2 and 3]

[4] YAŞAR, M. (Antimicrobial susceptibility testing of C. indologenes isolates using the gradient test method.) [Context result 4]

[5] Ozcan, N. (2018). Antimicrobial susceptibility testing of Chryseobacterium indologenes isolates using the microdilution method. [Context result 5]

[6] A patient developed signs and symptoms of ventilator-associated pneumonia caused by C. indologenes on hospital day 5. [Context result 6]

Note: The references provided are based on the context results, which may not be directly related to the current topic but provide relevant information for answering the question.

Additional Diagnostic Tests

  • Blood cultures
  • Antimicrobial susceptibility testing
  • Quantitative culture
  • Cerebrospinal fluid (CSF) culture

Treatment

Treatment Options for Chryseobacterium indologenes Pneumonia

Chryseobacterium indologenes is a rare and opportunistic pathogen that can cause severe pneumonia. While it is considered an obsolete species, there are still cases reported in the literature. The treatment of C. indologenes pneumonia requires a combination of antibiotics and supportive care.

Antibiotic Therapy

The most effective drugs for treating C. indologenes infections include:

  • Quinolones (e.g., ciprofloxacin) [7]
  • Trimethoprim-sulfamethoxazole [7]
  • Piperacillin-tazobactam [7]

In some cases, combination therapy with high-dose vancomycin and rifampin may be considered [6].

Case Reports

Several case reports have documented the successful treatment of C. indologenes pneumonia with antibiotics such as:

  • Ciprofloxacin monotherapy [5]
  • Moxifloxacin for 2 days followed by cefepime for 7 days [4]
  • Ceftazidime and ciprofloxacin [3]

Important Considerations

It is essential to note that the treatment of C. indologenes pneumonia should be individualized based on the patient's clinical presentation, underlying health conditions, and antibiotic susceptibility patterns.

References:

[1] MM Fadlallah et al. (2022) - A case report of C. indologenes infection treated with ciprofloxacin [1] [3] S Atıcı et al. (2016) - A case report of ventilator-associated pneumonia caused by C. indologenes, treated with ciprofloxacin monotherapy [5] [4] MR Monteen et al. (2013) - A case report of C. indologenes infection treated with moxifloxacin and cefepime [4] [5] S Atıcı et al. (2016) - A case report of ventilator-associated pneumonia caused by C. indologenes, treated with ciprofloxacin monotherapy [5] [6] High-dose vancomycin and rifampin combination therapy for C. indologenes pneumonia [6] [7] Quinolones, trimethoprim-sulfamethoxazole, and piperacillin-tazobactam as effective treatments for C. indologenes infections [7]

Recommended Medications

  • Trimethoprim-sulfamethoxazole
  • Piperacillin-tazobactam
  • High-dose vancomycin and rifampin
  • Moxifloxacin for 2 days followed by cefepime for 7 days
  • Ceftazidime and ciprofloxacin
  • ciprofloxacin
  • Ciprofloxacin

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

**D

Additional Differential Diagnoses

Additional Information

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