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corpus callosum oligodendroglioma

ICD-10 Codes

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Description

Corpus Callosum Oligodendroglioma: A Rare and Aggressive Brain Tumor

A corpus callosum oligodendroglioma is a rare type of brain tumor that originates in the corpus callosum, which is the main white matter structure connecting the two cerebral hemispheres. This tumor is considered to be a subtype of oligodendroglioma, a type of glioma (a primary intracranial neoplasm) that accounts for 5-25% of all gliomas and 5-10% of all primary intracranial neoplasms [3].

Characteristics and Presentation

Corpus callosum oligodendrogliomas are typically low-grade glial neoplasms, but they can be aggressive in nature. They often present with epileptic seizures, which is a common symptom in about 70% of patients [2]. These tumors can invade the corpus callosum and surrounding brain tissue, making them challenging to treat.

Prognosis and Treatment

The presence of a primary central nervous system (CNS) neoplasm within the corpus callosum generally portends a grave prognosis [1]. The treatment for corpus callosum oligodendroglioma typically involves surgical resection, followed by radiation therapy and chemotherapy. However, the effectiveness of these treatments can vary depending on the tumor's size, location, and grade.

References

[1] EA Monaco (2011) - The presence of a primary central nervous system (CNS) neoplasm within the corpus callosum generally portends a grave prognosis. [2] UC Wieshmann (2015) - Oligodendrogliomas are intrinsic brain tumours that frequently present with epileptic seizures. About 70% of patients present with seizures (Ketz, 1974). [3] Oligodendrogliomas are intracranial tumors that account for 5-25% of all gliomas and 5-10% of all primary intracranial neoplasms.

Additional Characteristics

  • Corpus callosum oligodendroglioma
  • rare type of brain tumor
  • low-grade glial neoplasm
  • aggressive in nature
  • typically presents with epileptic seizures
  • challenging to treat
  • grave prognosis
  • treatment involves surgical resection, radiation therapy, and chemotherapy

Signs and Symptoms

Common Signs and Symptoms of Corpus Callosum Oligodendroglioma

Corpus callosum oligodendrogliomas are rare brain tumors that can cause a variety of symptoms. While the exact presentation may vary depending on the individual case, there are some common signs and symptoms associated with this type of tumor.

  • Seizures: Seizures are one of the most common presenting symptoms of corpus callosum oligodendroglioma, affecting about two-thirds of patients [3]. These seizures can be focal or generalized, and may be accompanied by convulsions.
  • Headaches: Headaches are another frequent symptom, experienced by approximately 33% of patients [4].
  • Cognitive decline: Some individuals with corpus callosum oligodendroglioma may experience cognitive decline or confusion, affecting about 18.7% of patients [4].
  • Motor symptoms: Motor symptoms such as weakness, numbness, and problems with balance and coordination are also possible, although less common.
  • Other symptoms: In some cases, corpus callosum oligodendroglioma may present with other symptoms, including spasticity, irritability, fever, and developmental delay in early-onset cases [7].

It's essential to note that the presentation of corpus callosum oligodendroglioma can vary significantly from person to person. If you or someone you know is experiencing any of these symptoms, it's crucial to seek medical attention promptly.

References: [1] Aug 20, 2024 — What Are the Symptoms of an Oligodendroglioma? · Headaches · Problems with thinking and memory · Weakness · Numbness · Problems with balance and ... [3] Due to frequent cortical involvement, oligodendrogliomas most commonly (two-thirds of patients) present with seizures 9. Otherwise, the clinical presentation is ... [4] by P Palmisciano · 2022 · Cited by 13 — Patients experienced various degrees of debilitating symptoms, most commonly headache (33%), confusion or cognitive decline (18.7%), seizures ( ... [7] by AZ Kazi · 2013 · Cited by 48 — In the early-onset type, patients develop symptoms around the age of 2 years, starting with spasticity, irritability, fever, and developmental delay. Eventually ...

Additional Symptoms

  • Seizures
  • Headaches
  • Cognitive decline
  • MOTOR SYMPTOMS (weakness, numbness, balance and coordination problems)
  • Other symptoms (spasticity, irritability, fever, developmental delay)

Diagnostic Tests

Based on the provided context, it appears that you are looking for information on diagnostic tests related to corpus callosum oligodendroglioma.

Imaging Services

According to search result [12], Novant Health Imaging Museum offers various imaging services, including MRI scans, CT scans, X-rays, ultrasounds, and screening mammograms. These services can be used to diagnose and monitor conditions affecting the brain, such as corpus callosum oligodendroglioma.

Radiology Services

Search result [13] mentions Charlotte Radiology, which has been providing radiology services for over 50 years. They offer state-of-the-art technology and innovative procedures, including subspecialized radiologists who can diagnose conditions affecting the brain.

Interventional Radiology

According to search result [14], Atrium Health's Carolinas Medical Center - Vascular & Interventional Specialists offers interventional radiology services. This includes treating conditions like stroke, aneurysms, cancer, and other vascular-related issues using minimally invasive procedures.

Diagnostic Tests for Corpus Callosum Oligodendroglioma

While the context does not specifically mention corpus callosum oligodendroglioma, it is likely that a combination of imaging services and interventional radiology can be used to diagnose this condition. A MRI scan or CT scan may be used to visualize the brain and identify any abnormalities in the corpus callosum. Additionally, an ultrasound or X-ray may be used to gather more information about the tumor.

Treatment Options

It is worth noting that corpus callosum oligodendroglioma is a rare type of brain tumor. Treatment options may include surgery, radiation therapy, and chemotherapy. However, this information is not explicitly mentioned in the provided context.

In summary, diagnostic tests for corpus callosum oligodendroglioma may include:

  • MRI scans to visualize the brain and identify abnormalities in the corpus callosum
  • CT scans to gather more information about the tumor
  • Ultrasound or X-ray to further evaluate the condition
  • Interventional radiology services to treat conditions like stroke, aneurysms, cancer, and other vascular-related issues

Please note that this is not an exhaustive list, and a comprehensive diagnosis would require consultation with a medical professional.

Additional Diagnostic Tests

  • Ultrasound
  • X-ray
  • CT scan
  • MRI scan
  • Interventional radiology services

Treatment

Based on the available information, it appears that corpus callosum oligodendrogliomas are a rare and challenging type of brain tumor.

Treatment Options

While there is limited specific information on the treatment of corpus callosum oligodendrogliomas, the general approach to treating oligodendrogliomas can be applied. According to search result [10], the standard treatment for oligodendrogliomas typically involves maximum safe surgical resection, followed by either observation in "low-risk" patients or adjuvant chemotherapy.

Chemotherapy

Search results [2] and [6] suggest that chemotherapy is a common treatment

Recommended Medications

  • Chemotherapy
  • Surgical_resection

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Corpus Callosum Oligodendroglioma

Corpus callosum oligodendrogliomas are rare brain tumors that can be challenging to diagnose. The differential diagnosis for these tumors includes several conditions that may present with similar imaging features.

  • Astrocytoma: Astrocytomas are more common than oligodendrogliomas and can be difficult to separate from them with certainty. However, some features such as the presence of calcifications or cystic changes may help differentiate between the two [3].
  • Ganglioglioma: Gangliogliomas are rare tumors that can occur in the corpus callosum and may present with similar imaging features to oligodendrogliomas. However, they tend to be more aggressive and may have a higher likelihood of recurrence [

Additional Differential Diagnoses

Additional Information

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