catecholaminergic polymorphic ventricular tachycardia 5

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) Description

CPVT is a heart rhythm problem, or arrhythmia. If you have it, your heartbeat is faster and irregular at times [5]. This condition can cause an abnormal heart rhythm that can be life-threatening [3].

Key Features of CPVT:

• Faster and irregular heartbeat
• Can be triggered by exercise or emotional stress
• May lead to potentially life-threatening arrhythmias

Note: The information provided is based on the search results, specifically description 5 in the context.

Common Signs and Symptoms of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare heart condition that can cause sudden rhythm disturbances, leading to fainting or even death. The symptoms of CPVT can vary from person to person but often include:

• Fainting or feeling like fainting: This is one of the most common symptoms of CPVT, especially when exercising or engaging in physical activity [5].
• Dizziness and light-headedness: People with CPVT may experience dizziness or a feeling of being lightheaded

Diagnostic Tests for Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare heart condition that can be diagnosed through various tests. Here are some of the diagnostic tests used to diagnose CPVT:

• Treadmill Stress Testing: This test involves exercising on a treadmill while your heart rate and rhythm are monitored. It's often the first line of testing for CPVT, as it can provoke heart rhythm abnormalities in individuals with the condition.
• Holter Monitoring: This test involves wearing a portable device that monitors your heart rhythm over a 24-hour period. It can help diagnose CPVT by detecting abnormal heart rhythms during exercise or at rest.
• Implantable Loop Recorder (ILR): An ILR is a small device implanted under the skin to monitor your heart rhythm continuously for up to three years. It's often used in individuals with symptoms of CPVT who have not responded to other tests.

These diagnostic tests can help confirm a diagnosis of CPVT, which is essential for developing an effective treatment plan and managing the condition.

References:

• [5] - Your doctor will diagnose CPVT either through: treadmill stress testing to provoke heart rhythm abnormalities. Holter monitoring, and/or implantable loop recorder (ILR) monitoring.
• [8] - Typical findings include polymorphic ventricular tachycardia (fast abnormal heart rhythm).

Long-term treatments for CPVT

According to search result [5], long-term treatments for Catecholaminergic Polymorphic Ventricular Tachycardia

Differential Diagnosis of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Catecholaminergic polymorphic ventricular tachycardia (CPVT) can be challenging to diagnose, and it is often misdiagnosed as other conditions. Some of the differential diagnoses for CPVT include:

• Long QT Syndrome (LQTS): LQTS type 1 (LQT1) is a condition that phenotypically mimics CPVT but has a relatively better prognosis [12].
• Vasovagal Syncope: Vasovagal syncope can be initially attributed to neurological causes, leading to a delay in diagnosis of ≥2 years in patients with syncope [14].
• Exercise-Induced Long QT Syndrome (LQTS): This condition is caused by mutations in the cardiac ryanodine receptor gene (RYR2) or the cardiac calsequestrin gene CASQ2, which can also cause CPVT [15].

Key Points to Consider

• CPVT is a rare inherited arrhythmia syndrome characterized by exercise- or emotional stress-induced bidirectional or polymorphic ventricular tachycardia.
• The condition often presents with syncope and sudden cardiac death at a young age, in the absence of structural heart disease [5].
• A mean delay in diagnosis of ≥2 years is usually reported in patients with syncope initially attributed to vasovagal or neurological causes [14].

References

[5] by A Leenhardt · 2012 · Cited by 192 — CPVT occurs in children and adolescents and causes syncope and sudden cardiac death at a young age, in the absence of structural heart disease. [12] Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been often misdiagnosed as long QT syndrome (LQTS) type 1 (LQT1), which phenotypically mimics CPVT but has a relatively better prognosis. [14] A mean delay in diagnosis of ≥2 years is usually reported in patients with syncope initially attributed to vasovagal or neurological causes. ... RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long ... [15] Background: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is an inherited arrhythmia syndrome, characterised by polymorphic ventricular tachycardia induced by adrenergic stress. CPVT can be caused by mutations the cardiac ryanodine receptor gene (RYR2) or mutations in the cardiac calsequestrin gene CASQ2.