atrophoderma vermiculata

Atrophoderma vermiculata, also known as keratosis pilaris atrophicans, is a rare skin disorder that typically presents in childhood.

Characteristics:

• Erythema and follicular keratotic papules on the cheeks, preauricular area, and forehead [1][3][4]
• Slow progression to characteristic atrophy, described as worm-eaten, reticular, or honeycomb [1][3][4]
• Atrophy may extend to the upper lip, helices, ear lobes, and other areas in some cases [1]

Key Features:

• Typically presents in childhood
• Erythematous follicular papules on the cheeks
• Gradual progression to atrophy with characteristic worm-eaten or honeycomb appearance

References:

[1] Atrophoderma vermiculata is a form of keratosis pilaris atrophicans that typically presents in childhood with erythema and follicular keratotic papules that slowly progress to characteristic atrophy.

[3] Description. An abnormality of the morphology of the epidermis. Synonym. Abnormality of epidermal morphology. Open detail view . ... Atrophoderma vermiculata is caused by genetic mutations, also known as pathogenic variants.

[4] Atrophoderma vermiculata, a form of keratosis pilaris atrophicans, typically presents in childhood with erythema and follicular keratotic papules that slowly progress to characteristic atrophy, which has been described as worm-eaten, reticular, or honeycomb, and occurs on the cheeks, preauricular area, and forehead.

Atrophoderma vermiculatum, also known as folliculitis ulerythematosa reticulata, is a rare variant of keratosis pilaris atrophicans. The clinical signs and symptoms of this condition are quite distinctive.

Key Signs and Symptoms:

• Perifollicular atrophy: This results in a honeycombed worm-eaten appearance on the skin, resembling severe acne scarring [1].
• Follicular atrophic scars: These can be found on the facial skin, particularly on the cheeks [6].
• Generalized facial erythema: A redness of the face is often observed in patients with atrophoderma vermiculata.
• Sparse open and closed comedones: Small bumps or blackheads can appear on the skin.
• Milia: Tiny white bumps can also be present.

Additional Signs:

• Linear, reticulated, or serpiginous furrows: These are characteristic linear patterns that can appear on the skin [8].
• Small elevated benign lesions: These can resemble a patch of tiny goose bumps [7].

These signs and symptoms can vary in severity and presentation from one individual to another. If you're looking for more information, I'd be happy to help!

Diagnostic Tests for Atrophoderma Vermiculatum

Atrophoderma vermiculatum, also known as folliculitis ulerythematosa reticulata, is a rare variant of keratosis pilaris atrophicans. Diagnostic tests are essential to confirm the diagnosis and rule out other conditions with similar symptoms.

Available Genetic Tests

Genetic tests for Atrophoderma vermiculatum are available in the US and labs around the world [1]. These tests can help identify the genetic mutations associated with the condition.

Laboratory Tests

Laboratory tests, such as blood or DNA samples, may be required to confirm the diagnosis [6]. A 5 mL whole blood or DNA sample is typically needed for these tests.

Diagnostic Aids and Test Guides

Several diagnostic aids and test guides are available online, including those provided by Eurofins Biomnis [5]. These resources can help healthcare professionals diagnose Atrophoderma vermiculatum accurately.

Differential Diagnosis

It's essential to consider differential diagnosis when evaluating patients with symptoms of Atrophoderma vermiculatum. Anetoderma and morphea are two conditions that may be confused with Atrophoderma vermiculatum [7].

References:

• [1] Clinical resource with information about Atrophoderma vermiculatum and its clinical features, available genetic tests from US and labs around the world...
• [5] Diagnostic aids · News · Test guide · About us ... Eurofins BiomnisTest guideGenetics test guideAtrophoderma vermiculata ...
• [6] Disease code: ORPHA:79100 · Associated therapeutic area(s):. Abnormality of the musculoskeletal system (HP:0033127) · Prenalytics: 5 mL whole blood or DNA sample
• [7] Differential diagnosis​​ 1. Atrophoderma may be an atrophic end-stage lesion of morphea (9.3). 2. Anetoderma has a similar name, but is completely different (9. ...

Atrophoderma vermiculatum, also known as Atrophoderma vermiculata, is a rare genodermatosis characterized by a "honey-combed" reticular atrophy of the cheeks. While there are various therapeutic modalities that have been used to treat this condition, the effectiveness of these treatments can vary.

Treatment Options:

• Dermabrasion: This surgical procedure has been used to treat atrophoderma vermiculatum, but its effectiveness is unclear [1][3].
• Cryotherapy: Cryotherapy has also been tried as a treatment option, but it has proven ineffective in treating this condition [7].
• Ultraviolet (UV) therapy: UV therapy has been used to treat various skin conditions, but its effectiveness in treating atrophoderma vermiculatum is unknown.
• Laser treatment: Laser treatment, specifically the 595 nm pulsed dye laser and carbon dioxide laser, have been applied for a case of unilateral atrophoderma vermiculatum [9]. However, more research is needed to confirm its effectiveness.

Current Treatment Status:

Unfortunately, there is no effective treatment available for atrophoderma vermiculatum. Procedures such as cryotherapy, phototherapy, and keratolytic treatment have proven ineffective in treating this condition [7].

It's essential to note that the course of atrophoderma vermiculatum is generally slow, with progressive worsening [3]. Therefore, a multidisciplinary approach involving dermatologists, surgeons, and other healthcare professionals may be necessary to manage this condition.

References:

[1] Handrick C. (2001). Atrophoderma vermiculata: A rare genodermatosis. [1]

[3] Handrick C. (2001). As treatment options for this mostly cosmetic condition, a variety of therapeutic modalities have been used... [3]

[7] GyL F. (1997). The disease has no effective treatment. Procedures such as cryotherapy, phototherapy, keratolytic treatment have proven ineffec- tive. [7]

[9] Oct 22, 2024. Treatment of either modality. In conclusion, 595 nm pulsed dye laser and carbon di-. oxide laser were applied for a case of unilateral atropho-. [9]

Differential Diagnosis of Atrophoderma Vermiculatum

Atrophoderma vermiculatum, also known as folliculitis ulerythematosa reticulata, is a rare variant of keratosis pilaris atrophicans. When considering the differential diagnosis for this condition, several other skin conditions must be taken into account.

• Keratosis Pilaris Atrophicans Faciei: This is a related condition that shares similar characteristics with atrophoderma vermiculatum.
• Erythromelanosis Follicularis Faciei et Colli: A rare dermatosis characterized by erythema and hyperpigmentation of the face and neck, which can be confused with atrophoderma vermiculatum.
• Keratosis Pilaris Rubra Faciei: A condition that presents with red, follicular keratoses on the face, which may be mistaken for atrophoderma vermiculatum.
• Lupus Erythematosus: An autoimmune disease that can cause atrophic scars on the face, which may be confused with atrophoderma vermiculatum.
• Varicella and Acne: Other conditions that can present with atrophic scars or follicular lesions, which must be ruled out in the differential diagnosis of atrophoderma vermiculatum.

According to [4], Atrophoderma Vermiculatum (AV) is a rare disease that should be considered in the differential diagnosis of facial dermatoses. The condition may also be associated with other congenital abnormalities and hereditary diseases, such as Marfan syndrome and neurofibromatosis [5].

In addition, atrophodermia vermiculata is a rare inflammatory follicular atrophic condition which must be considered in the differential diagnosis of acne [9]. It's essential to consider these conditions when diagnosing atrophoderma vermiculatum to ensure accurate treatment and management.

References: [1] - Atrophoderma vermiculatum (AV), also known as folliculitis ulerythematosa reticulata, is a rare variant of keratosis pilaris atrophicans. [4] - Atrophoderma Vermiculatum (AV) is a rare disease ... [Early and late histologic aspects of atrophodermia vermiculata. ... Diagnosis, Differential; Facial Dermatoses ... [5] - This type of dermatosis may be associated with other congenital abnormalities and some hereditary diseases, such as Marfan syndrome, neurofibromatosis, ... [9] - Atrophodermia vermiculata is a rare inflammatory follicular atrophic condition which must be considered in the differential diagnosis of acne ...