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age related macular degeneration 5
Description
Age-related Macular Degeneration (AMD) Description
Age-related macular degeneration (AMD) is an eye condition causing central vision loss, mostly affecting those older than 50 [5]. This condition can result in severe loss of central vision, making everyday activities such as reading, driving, and recognizing faces challenging.
Key Points:
- Affects central vision
- Primarily affects individuals over 50 years old
- Can cause significant visual impairment
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Additional Characteristics
- Affects central vision
- Primarily affects individuals over 50 years old
- Can cause significant visual impairment
Signs and Symptoms
Early Signs and Symptoms of Age-related Macular Degeneration (AMD)
Age-related macular degeneration (AMD) is a condition that affects the macula, the part of the retina responsible for central vision. The early signs and symptoms of AMD can be subtle, but it's essential to recognize them to seek medical attention.
- Loss of Central Vision: One of the earliest signs of AMD is loss of central vision, which can make it difficult to read, watch TV, or perform other daily activities that require clear vision (5).
- Blurred or Distorted Area in Vision: The first symptom of AMD is often a blurred or distorted area in your vision. This can be a small spot or a larger area, and it may appear as a smudge on glasses (4).
As AMD progresses, the symptoms can worsen, making it challenging to perform daily tasks that require clear central vision.
References:
- [5] Jun 7, 2024 — What are the symptoms of macular degeneration? ... Some early signs can be loss of central vision. A person may notice that when they're reading, ...
- [4] The first symptom is often a blurred or distorted area in your vision. ... If it gets worse, you might struggle to see anything in the middle of your vision.
- [3] Nov 23, 2022 — Symptoms · Visual distortions, such as straight lines seeming bent. · Reduced central vision in one or both eyes. · The need for brighter light ...
- [1] Painful eye inflammation (iritis or uveitis) and sensitivity to light (photophobia). A feeling of pressure behind your eye. Eye floaters or flashers. What ... Note: These symptoms are not specific to AMD, but rather a general overview of potential eye issues.
- [2] Jun 22, 2021 — At a glance: AMD ; Early Symptoms: None ; Later Symptoms: Loss of the central vision you need to see details straight ahead, blurry or wavy areas ...
- [6] What are the symptoms? · Gaps or dark spots (like a smudge on glasses) may appear in your vision, especially first thing in the morning. · Colours can fade. · You ...
- [7] Sep 11, 2024 — Dark, blurry areas in the center of your vision; Straight lines look wavy. Worse or different color perception; Trouble seeing in low light ...
Additional Symptoms
- Visual distortions, such as straight lines seeming bent.
- Reduced central vision in one or both eyes.
- The need for brighter light.
- Painful eye inflammation (iritis or uveitis) and sensitivity to light (photophobia). A feeling of pressure behind your eye. Eye floaters or flashers.
- Gaps or dark spots (like a smudge on glasses) may appear in your vision, especially first thing in the morning.
- Colours can fade.
- Dark, blurry areas in the center of your vision;
- Straight lines look wavy.
- Worse or different color perception;
- Trouble seeing in low light
- loss of vision
- blurred vision
Diagnostic Tests
Diagnostic Tests for Age-related Macular Degeneration (AMD)
Age-related macular degeneration (AMD) can be diagnosed through various tests that check your vision and examine the retina at the back of your eye. Here are some diagnostic tests used to detect AMD:
- Visual Acuity Test: This test checks your central vision by asking you to read letters or numbers on a chart. It helps determine if you have any visual impairment.
- Ophthalmoscopy: Your doctor uses an ophthalmoscope to examine the retina and look for signs of AMD, such as drusen (yellow deposits) or blood vessels that are leaking fluid.
These tests can help your eye doctor confirm a diagnosis of macular degeneration. It's essential to have regular eye exams to detect any changes in your vision and catch AMD early on.
References:
- [5] Your doctor will check for AMD by testing your vision and examining your retina, a layer of tissue at the back of your eye that processes light.
- [8] Diagnosing age-related macular degeneration (AMD) requires an eye examination performed by an eye health professional – an optometrist or ophthalmologist.
Additional Diagnostic Tests
- Visual Acuity Test
- Ophthalmoscopy
Treatment
Treatment Options for Wet Age-related Macular Degeneration (AMD)
Wet AMD, a more severe form of age-related macular degeneration, can be treated with various medications and therapies. Here are some of the most commonly used treatment options:
- Anti-VEGF Agents: These injections block the production of vascular endothelial growth factor (VEGF), a protein that promotes blood vessel growth in the eye. Examples include:
- Aflibercept (Eylea)
- Ranibizumab (Lucentis)
- Bevacizumab (Avastin)
- Brolucizumab-dbll (Beovu)
- Faricimab-svoa (Vabysmo) [5]
- Photodynamic Therapy: This two-step treatment uses a light-sensitive drug to damage abnormal blood vessels in the eye. [6]
These treatments can help stabilize or improve vision in patients with wet AMD, but they do not cure the condition.
References:
[1] Context 7 [2] Context 8 [3] Context 4 [4] Context 5
Recommended Medications
- Bevacizumab (Avastin)
- Ranibizumab (Lucentis)
- Aflibercept (Eylea)
- Faricimab-svoa (Vabysmo)
- Brolucizumab-dbll (Beovu)
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Age-related Macular Degeneration (AMD) Differential Diagnoses
Age-related macular degeneration (AMD) can be challenging to diagnose, particularly in the age group commonly affected. When it occurs, the differential diagnosis between the macular lesion and wet AMD may be difficult.
Some of the key differential diagnoses for AMD include:
- Other genetic macular diseases: Such as Stargardt disease, Best disease, and pattern dystrophy [1].
- Angioid streaks: A condition characterized by breaks in Bruch's membrane, which can lead to vision loss [2].
- Central Serous Chorioretinopathy (CSCR): A condition where fluid accumulates under the retina, causing visual disturbances [3].
- Choroidal Melanoma: A type of cancer that affects the choroid layer of the eye [4].
- Choroidal Neovascularization (CNV): The growth of new blood vessels in the choroid layer, which can lead to vision loss [5].
It's essential to consider these differential diagnoses when evaluating patients with suspected AMD. A comprehensive diagnostic workup, including imaging studies and clinical examination, is crucial for accurate diagnosis and treatment planning.
References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 2 [4] - Context result 3 [5] - Context result 2
Additional Differential Diagnoses
- Other genetic macular diseases
- Central Serous Chorioretinopathy (CSCR)
- Choroidal Melanoma
- Choroidal Neovascularization (CNV)
- angioid streaks
Additional Information
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- IAO_0000115
- An age related macular degeneration onferred by heterozygous mutation in the ERCC6 gene on chromosome 10q11.
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.