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obsolete eyelid degenerative disease
Description
Obsolete Eyelid Degenerative Disease
The context suggests that there are several rare and obscure conditions related to the eyelids, but one specific condition stands out as an "obsolete" eyelid degenerative disorder.
According to search result [5], Blepharospasm is a common adult-onset focal dystonia, characterized by involuntary contractions of the periocular muscles resulting in forceful eye closure. However, this does not seem to be the condition being referred to as "obsolete".
Search result [15] mentions Eyelid degenerative disorder, which is described as a neurodegenerative disease that involves the eyelid. This condition is listed under MedGen UID: 509851 and Concept ID: C0155209.
Another search result [3] mentions Kearns-Sayre syndrome (KSS), a rare multisystemic disorder characterized by ptosis (droopy eyelids) among other symptoms. However, this does not seem to be the condition being referred to as "obsolete".
It's worth noting that search result [15] describes Eyelid degenerative disorder as a neurodegenerative disease, which is different from the other conditions mentioned.
Key Features:
- Neurodegenerative disease
- Involves the eyelid
- Listed under MedGen UID: 509851 and Concept ID: C0155209
Please note that this information might be outdated or obsolete as per search result [15] itself.
Signs and Symptoms
Based on the provided context, it appears that there are several signs and symptoms associated with an obsolete eyelid degenerative disease.
Primary Clinical Features
- Droopy eyelids (ptosis) in one or both eyes [3]
- Presence of droopy eyelids is a significant clinical symptomatic feature [3]
Other Symptoms
- Swelling in the white parts of your eye and puffy tissue around your eyes [1]
- Eyelid openings that are wider than normal, bulging eyes, and misaligned eyes that don't seem to focus on the same point [6]
- Decrease in corneal sensation, with punctate epithelial lesions in stage 1 disease [7]
Additional Symptoms
- Dry and irritated eyes due to inability to fully close eyelids (lagophthalmos) [2]
- Episodes of increased tearing, watery eyes, and tear dripping over the lid margin due to tissue alterations [9]
It's worth noting that this information appears to be related to an outdated or obsolete disease, as it is not commonly discussed in modern medical literature. However, based on the provided context, these symptoms may have been associated with a specific eyelid degenerative disease in the past.
References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 3 [6] - Context result 6 [7] - Context result 7 [9] - Context result 9
Additional Symptoms
- Droopy eyelids (ptosis) in one or both eyes
- Swelling in the white parts of your eye and puffy tissue around your eyes
- Eyelid openings that are wider than normal, bulging eyes, and misaligned eyes that don't seem to focus on the same point
- Decrease in corneal sensation, with punctate epithelial lesions in stage 1 disease
- Dry and irritated eyes due to inability to fully close eyelids (lagophthalmos)
- Episodes of increased tearing, watery eyes, and tear dripping over the lid margin due to tissue alterations
Diagnostic Tests
Treatment
Based on the provided context, it appears that there are some outdated or less common eye diseases related to eyelid degeneration. However, I was able to find some relevant information on a condition called Demodex blepharitis.
Demodex blepharitis is a condition caused by an infestation of Demodex mites in the eyelids. According to search result 3, the use of 4% pilocarpine gel demonstrated complete resolution of Demodex blepharitis in 37.5% of cases, and partial cure in 40.6% of cases.
It's worth noting that this information is related to a specific treatment option for Demodex blepharitis, which might not be directly applicable to other obsolete eyelid degenerative diseases. However, it provides some insight into the potential effectiveness of topical treatments for certain eye conditions.
Additionally, search result 14 mentions ocular drug delivery systems for treating diseases affecting the anterior segment of the eye, including those related to the eyelids. This information might be relevant to understanding the current state of treatment options for various eye conditions, although it does not specifically address obsolete eyelid degenerative diseases.
In summary:
- Demodex blepharitis can be treated with 4% pilocarpine gel, which showed complete resolution in 37.5% of cases and partial cure in 40.6% of cases [3].
- Ocular drug delivery systems are being developed for treating various eye conditions affecting the anterior segment, including those related to the eyelids [14].
Please note that these findings might not be directly applicable to other obsolete eyelid degenerative diseases, and further research would be necessary to determine the most effective treatment options.
Differential Diagnosis
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:10120
- core#notation
- DOID:10120
- oboInOwl#hasDbXref
- UMLS_CUI:C0155209
- rdf-schema#comment
- category only, removed[LS]
- rdf-schema#label
- obsolete eyelid degenerative disease
- owl#deprecated
- true
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_6936
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