You have 1 free disease view remaining today. Register for more view, it is 100% free โ
subendocardial infarction acute myocardial infarction
Description
Based on the provided context, here's a description of subendocardial infarction and its relation to acute myocardial infarction:
Subendocardial infarction refers to a type of heart attack where there is necrosis (death) of the innermost layer of the heart muscle, specifically the endocardium. This occurs when there is a lack of oxygen supply to this area, often due to a blockage in one or more coronary arteries.
In the context of acute myocardial infarction (AMI), subendocardial infarction is considered a type of AMI where the damage is limited to the innermost layer of the heart muscle. This is different from other types of AMI, such as ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI), which involve more extensive damage to the heart muscle.
Subendocardial infarction is often characterized by:
- Typical chest pain that lasts for 15 minutes or more
- Serum enzyme elevation and persistent new T-wave inversion on an electrocardiogram (ECG)
- Lack of oxygenation despite circulation, such as in cases of respiratory arrest
It's worth noting that the term "subendocardial infarction" is sometimes used interchangeably with "subendocardial myocardial infarction," but they both refer to the same condition.
In terms of treatment and prognosis, subendocardial infarction is often managed similarly to other types of AMI, with a focus on restoring blood flow to the affected area and preventing further damage. However, the specific management plan may vary depending on individual patient factors and the extent of the infarct.
Additional Characteristics
- Necrosis (death) of the innermost layer of the heart muscle, specifically the endocardium.
- Typical chest pain that lasts for 15 minutes or more
- Serum enzyme elevation and persistent new T-wave inversion on an electrocardiogram (ECG)
- Lack of oxygenation despite circulation, such as in cases of respiratory arrest
Signs and Symptoms
Common Signs and Symptoms of Subendocardial Infarction Acute Myocardial Infarction
Subendocardial infarction, also known as non-ST-segment elevation myocardial infarction (NSTEMI), is a type of heart attack that occurs when the blood flow to the innermost layer of the heart muscle (subendocardium) is blocked. The symptoms and signs of subendocardial infarction can be similar to those of other types of heart attacks, but may also include:
- Chest pain or discomfort: This is often described as a squeezing, pressure, or tightness sensation in the chest, which may radiate to the arm or jaw [7][8].
- Shortness of breath: People with subendocardial infarction may experience difficulty breathing or feeling winded even when sitting still [10].
- Nausea and vomiting: Some individuals may feel queasy or vomit due to the pain and discomfort caused by the heart attack [4][9].
- Fatigue: Feeling extremely tired or weak is another common symptom of subendocardial infarction [10].
- Accumulation of fluid under the skin: In some cases, people with subendocardial infarction may experience swelling in their legs, ankles, or feet due to fluid buildup [10].
It's essential to note that women are more likely to experience symptoms other than chest pain, such as nausea and vomiting, when having a heart attack [9]. If you or someone you know is experiencing any of these symptoms, it's crucial to seek medical attention immediately.
References:
[1] Context result 11 [2] Context result 12 [3] Context result 14 [4] Context result 4 [5] Context result 7 [6] Context result 8 [7] Context result 7 [8] Context result 8 [9] Context result 9 [10] Context result 10
Additional Symptoms
- Nausea and vomiting
- Shortness of breath
- Chest pain or discomfort
- Accumulation of fluid under the skin
- fatigue
Diagnostic Tests
Diagnostic Tests for Subendocardial Infarction and Acute Myocardial Infarction
Subendocardial infarction, also known as non-ST-segment elevation myocardial infarction (NSTEMI), is a type of acute myocardial infarction that occurs when the blood flow to the innermost layer of the heart muscle (subendocardium) is blocked. Diagnosing subendocardial infarction and acute myocardial infarction requires a combination of clinical evaluation, electrocardiography (ECG), laboratory tests, and imaging studies.
Electrocardiography (ECG)
The ECG is the most important tool in the initial evaluation and triage of patients with suspected acute myocardial infarction. While the ECG may not always show specific changes for subendocardial infarction, it can help identify other types of cardiac damage [6]. The presence of ST-segment elevation or depression, T-wave inversion, or Q-waves on the ECG can indicate myocardial injury.
Laboratory Tests
Several laboratory tests are used to diagnose acute myocardial infarction and subendocardial infarction. These include:
- High-sensitivity cardiac troponins: These are the preferred standard for establishing a biomarker diagnosis of acute myocardial infarction [13]. Elevated levels of high-sensitivity cardiac troponin can indicate myocardial injury.
- Creatine kinase (CK): CK is an enzyme that is released into the bloodstream when heart muscle is damaged. Elevated levels of CK can indicate myocardial damage, but this test is less specific than high-sensitivity cardiac troponins [5].
- Myoglobin: Myoglobin is a protein that is released into the bloodstream when heart muscle is damaged. Elevated levels of myoglobin can indicate myocardial damage, but this test is also less specific than high-sensitivity cardiac troponins [14].
Imaging Studies
Imaging studies are used to confirm the diagnosis and assess the extent of myocardial damage. These include:
- Echocardiography: Echocardiography uses sound waves to create images of the heart. It can help identify areas of wall motion abnormality, which can indicate myocardial damage [10].
- Cardiac magnetic resonance (CMR): CMR is a non-invasive imaging test that uses magnetic fields and radio waves to create detailed images of the heart. It can help identify areas of myocardial damage and assess the extent of infarction [11].
Other Diagnostic Tests
Other diagnostic tests may be used in conjunction with these tests to confirm the diagnosis and assess the extent of myocardial damage. These include:
- Coronary angiography: This is an invasive imaging test that uses a catheter to inject contrast dye into the coronary arteries, which are then imaged using X-rays [12].
- Stress testing: Stress testing involves exercising or using medication to increase heart rate and blood pressure, while monitoring ECG changes and symptoms. It can help identify areas of myocardial ischemia [9].
In conclusion, diagnosing subendocardial infarction and acute myocardial infarction requires a combination of clinical evaluation, electrocardiography, laboratory tests, and imaging studies. High-sensitivity cardiac troponins are the preferred standard for establishing a biomarker diagnosis of acute myocardial infarction.
Additional Diagnostic Tests
- Echocardiography
- Electrocardiography (ECG)
- Coronary angiography
- Cardiac magnetic resonance (CMR)
- Stress testing
- High-sensitivity cardiac troponins
- Creatine kinase (CK)
- Myoglobin
Treatment
Treatment Options for Subendocardial Infarction and Acute Myocardial Infarction
Subendocardial infarction, also known as a non-ST-elevation myocardial infarction (NSTEMI), is a type of heart attack that occurs when the blood flow to the subendocardium, the innermost layer of the heart muscle, is blocked. The treatment for subendocardial infarction and acute myocardial infarction (AMI) aims to restore blood flow to the affected area, reduce damage to the heart muscle, and prevent further complications.
Medications Used in Treatment
The medications used to treat subendocardial infarction and AMI include:
- Aspirin: Aspirin is often given immediately to patients with symptoms of a heart attack. It helps to reduce blood clotting and keep blood moving through the narrowed artery [1].
- Clot busters (thrombolytics or fibrinolytics): These medications are used to dissolve blood clots that have formed in the coronary arteries, restoring blood flow to the affected area [1].
- Beta blockers: Beta blockers, such as metoprolol and atenolol, can help reduce heart rate and blood pressure, decreasing oxygen demand on the heart muscle [8].
- ACE inhibitors: ACE inhibitors, such as lisinopril and enalapril, can help lower blood pressure and reduce strain on the heart muscle [9].
Other Treatment Options
In addition to medications, other treatment options for subendocardial infarction and AMI may include:
- Pain management: Pain relief is an important aspect of treating a heart attack. Medications such as morphine can help alleviate chest pain and discomfort.
- Oxygen therapy: Oxygen therapy may be necessary to ensure adequate oxygen supply to the affected area.
- Cardiac catheterization: Cardiac catheterization, also known as coronary angiography, is a procedure that uses a catheter to inject contrast dye into the coronary arteries. This can help identify blockages and guide treatment decisions.
References
[1] Context: Aspirin is often given immediately to patients with symptoms of a heart attack. It helps to reduce blood clotting and keep blood moving through the narrowed artery [1]. [8] Context: Beta blockers, such as metoprolol and atenolol, can help reduce heart rate and blood pressure, decreasing oxygen demand on the heart muscle [8]. [9] Context: ACE inhibitors, such as lisinopril and enalapril, can help lower blood pressure and reduce strain on the heart muscle [9].
Recommended Medications
- ACE inhibitors
- Beta blockers
- Clot busters (thrombolytics or fibrinolytics)
- acetylsalicylic acid
- Aspirin
๐ Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Subendocardial infarction and acute myocardial infarction (AMI) are two related but distinct cardiovascular conditions. The differential diagnosis between these two conditions is crucial for accurate treatment and management.
Similarities:
- Both subendocardial infarction and AMI involve damage to the heart muscle, leading to reduced cardiac function.
- Both conditions can cause chest pain, shortness of breath, and other symptoms related to cardiovascular distress.
Differential Diagnosis:
The key difference between subendocardial infarction and AMI lies in the extent and location of the heart muscle damage:
- Subendocardial Infarction: Refers to a type of myocardial infarction where the damage is limited to the innermost layer of the heart muscle (subendocardium). This condition is often associated with severe coronary artery disease, and the symptoms can be similar to those of AMI. [9]
- Acute Myocardial Infarction (AMI): Involves a larger area of heart muscle damage, extending beyond the subendocardium. AMI can be further classified into two types: ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). [10]
Differential Diagnosis Considerations:
When differentiating between subendocardial infarction and AMI, the following factors should be considered:
- Location of Damage: Subendocardial infarction is characterized by damage limited to the innermost layer of the heart muscle, whereas AMI involves a larger area of damage.
- Severity of Symptoms: Patients with subendocardial infarction may experience milder symptoms compared to those with AMI.
- Coronary Artery Disease: Severe coronary artery disease is often associated with subendocardial infarction.
References:
[9] NP Madigan ยท 1976 ยท Cited by 203 โ We conclude that subendocardial infarction is symptomatically an unstable entity, is associated with severe coronary artery disease. [10] Acute coronary syndrome (ACS) can be divided into subgroups of ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina.
Additional Information
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_7020
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:10266
- core#notation
- DOID:10266
- oboInOwl#hasDbXref
- UMLS_CUI:C0155655
- rdf-schema#label
- subendocardial infarction acute myocardial infarction
- rdf-schema#subClassOf
- http://purl.obolibrary.org/obo/DOID_9408
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
Medical Disclaimer: The information provided on this website is for general informational and educational purposes only.
It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.