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amnestic disorder

ICD-10 Codes

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Description

Amnestic disorder, also known as amnestic syndrome, is a condition that affects an individual's ability to learn new information or recall previously learned information [9]. It is characterized by a persistent impairment in memory formation and retrieval [10].

The symptoms associated with amnestic disorders include:

  • Loss of memory
  • Disorientation with time and space
  • Lack of insight to their loss of memory

Amnestic disorder can be caused by various factors, including physical injury, infection, or emotional trauma. In some cases, the memory loss is temporary, and the person eventually recovers [14].

There are different types of amnesia associated with amnestic disorders, such as:

  • Retrograde amnesia: Difficulty recalling events or information that occurred before onset of amnesia
  • Anterograde amnesia: Difficulty forming new memories

Amnestic disorder is a serious condition that can significantly impact an individual's daily life and functioning. It requires proper diagnosis and treatment to manage the symptoms and improve memory function [9].

References:

[9] Amnestic disorder is a persistent condition that impairs an individual's ability to learn new information or recall previously learned information. [10] Another rare type of amnesia, called dissociative amnesia, stems from emotional shock or trauma. It can result from being the victim of a violent crime or experiencing other trauma. [14] Amnesia is a memory disorder that can affect the ability to recall old memories (retrograde amnesia) and the ability to form new memories (anterograde amnesia).

Additional Characteristics

  • Loss of memory
  • Disorientation with time and space
  • Lack of insight to their loss of memory
  • Retrograde amnesia: Difficulty recalling events or information that occurred before onset of amnesia
  • Anterograde amnesia: Difficulty forming new memories

Signs and Symptoms

Signs and Symptoms of Amnestic Disorder

Amnestic disorder, also known as amnesia, is a condition characterized by difficulty forming new memories or recalling old ones. The primary symptom of amnestic disorder is memory loss, which can be brief or long-term.

  • Memory Loss: People with amnestic disorder may experience significant memory loss, including:
    • Forgetting recent events or conversations
    • Difficulty remembering names and faces
    • Trouble recalling locations and how to get there
    • Inability to learn new information [6][9]
  • Confusion and Disorientation: Amnestic disorder can also cause confusion and disorientation, making it difficult for individuals to:
    • Understand their surroundings
    • Keep track of time and space
    • Recognize familiar faces or places [8][9]
  • Anxiety and Difficulty Learning New Information: People with amnestic disorder may experience anxiety due to their memory loss and have difficulty learning new information, which can affect daily life [9]

It's essential to note that symptoms of amnestic disorder can be easily confused with other types of memory loss, such as dementia or Alzheimer's disease. However, amnestic disorder typically affects memory without affecting other cognitive abilities.

References:

  • [6] Difficulty recalling names and faces.
  • [8] Amnesia is a general term describing memory loss.
  • [9] Symptoms of Amnesia · Loss of memory · Anxiety for not understanding the memory loss · Disorientation with time and space · Difficulty learning new information ...
  • [10] Symptoms. Symptoms of mild cognitive impairment, also known as MCI, include trouble with memory, language and judgment.

Diagnostic Tests

Diagnostic Tests for Amnestic Disorder

Amnestic disorder, also known as anterograde amnesia, is a condition where an individual is unable to form new memories after a certain point in time. Diagnosing this condition requires a comprehensive evaluation of the patient's medical history, physical examination, and various diagnostic tests.

Tests Used for Diagnosis

The following tests are commonly used to diagnose amnestic disorder:

  • Imaging Tests: Imaging tests such as MRI (Magnetic Resonance Imaging) and CT scan (Computed Tomography scan) may be ordered to check for brain damage or changes such as shrinkage [1].
  • Physical Exam: A physical exam, including a neurological function test, is conducted to assess reflexes, strength, balance, vision, hearing, gait, motor strength, and control [2].
  • Medical History: The healthcare provider will ask questions regarding the patient's medical history, the nature of their memory loss, when it began, and whether other symptoms have accompanied their amnesia [2].
  • Routine Blood Tests: Routine blood tests assessing total blood count, liver, and kidney functions are often prescribed to diagnose the cause of memory loss [3].
  • Memory and Cognitive Tests: Memory and cognitive tests are conducted to assess problems with a person's ability to remember things and their ability to think, concentrate, and solve problems [5].

Additional Diagnostic Tools

Other diagnostic tools that may be used to diagnose amnestic disorder include:

  • Neuropsychological Assessment: A neuropsychological assessment is conducted to evaluate the patient's cognitive function and identify any areas of impairment.
  • Computed Tomography (CT) Scans: CT scans are used to rule out other conditions such as stroke, seizure, or head injury that may cause similar symptoms [10].
  • Magnetic Resonance Imaging (MRI): MRI scans are used to evaluate the brain for any damage or changes [6].

References

[1] Simon RP, et al. Dementia and amnestic disorders. In: Clinical Neurology. 10th ed. McGraw Hill; 2018.

[2] Medical history and physical exam are essential in diagnosing amnestic disorder.

[3] Routine blood tests are often prescribed to diagnose the cause of memory loss.

[5] Memory and cognitive tests are conducted to assess problems with a person's ability to remember things and their ability to think, concentrate, and solve problems.

[6] NYU Langone Health. (2022). Amnestic Disorder. Retrieved from https://www.nyulangone.org/conditions/amnestic-disorder

Note: The references provided are based on the information available in the search results and may not be an exhaustive list of all relevant sources.

Additional Diagnostic Tests

  • Physical Exam
  • Imaging Tests
  • Medical History
  • Magnetic Resonance Imaging (MRI)
  • Routine Blood Tests
  • Computed Tomography (CT) Scans
  • Memory and Cognitive Tests
  • Neuropsychological Assessment

Treatment

Treatment Options for Amnestic Disorder

Amnestic disorder, also known as amnesia, can be caused by various underlying conditions, including traumatic events, concussion, and neurological disorders. While there is no direct treatment or medication that can cure amnesia, addressing the underlying cause can help alleviate symptoms.

  • Medications aimed at some causes: If the amnesia is caused by an underlying medical condition such as early Alzheimer's disease, medications may be prescribed to manage symptoms.
  • Thiamin (Vitamin B1) treatment: In cases where amnesia is suspected to be due to alcohol abuse or other metabolic conditions, thiamin supplementation may be recommended to prevent further complications.
  • Treatment of underlying conditions: If the amnestic disorder is caused by a treatable condition such as depression, anxiety, bipolar disorder, schizophrenia, or substance abuse, treating these underlying conditions can help improve memory and cognitive function.

Key Points

  • Treatment for amnesia depends on the underlying cause [9].
  • Some forms of amnesia may be reversible with treatment [10].
  • Anterograde amnesia, a type of amnesia where new memories cannot be formed properly, may be treatable depending on the cause [11].

References

  • [8] Thiamin (Vitamin B1) treatment is recommended to prevent further complications in cases of suspected alcohol abuse.
  • [10] Some forms of amnesia are reversible with treatment.
  • [11] Anterograde amnesia may be treatable depending on the cause.

Recommended Medications

  • Medications for early Alzheimer's disease
  • Thiamin (Vitamin B1) supplementation for metabolic conditions or alcohol abuse

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Amnestic Disorder

Amnestic disorders are characterized by significant memory impairments that are not due to dementia or delirium. The differential diagnosis of amnestic disorders is crucial for accurate diagnosis and treatment.

  • Transient Global Amnesia: This condition is characterized by sudden, temporary loss of memory, typically lasting from a few minutes to 24 hours [8]. It can be caused by various factors, including migraines, seizures, or cardiac events.
  • Dissociative Amnesia: A subtype of dissociative disorders, dissociative amnesia is characterized by sudden, unexpected memory loss, often accompanied by fugue states (sudden travel or wandering) [10][11]. It can be caused by trauma, stress, or anxiety.
  • Amnestic Disorders due to General Medical Conditions: Certain medical conditions, such as hypoglycemia, subdural hematoma, or ischemia of the hippocampus, can cause amnesia [4][9].
  • Substance-Induced Amnestic Disorder: The use of certain substances, such as alcohol or benzodiazepines, can lead to memory impairments.
  • Dementia and Delirium: While not typically considered a differential diagnosis for amnestic disorders, dementia and delirium can also cause significant memory impairments.

Key Points

  • Amnestic disorders are characterized by significant memory impairments that are not due to dementia or delirium.
  • Differential diagnoses include transient global amnesia, dissociative amnesia, amnestic disorders due to general medical conditions, substance-induced amnestic disorder, and dementia/delirium.

References

[4] Alessandro, L. (2020). Acute Amnestic Syndromes: A Review of the Literature. [Context result 4] [8] Emergency Department Differential Diagnoses. (2022). [Context result 8] [9] Spiegel, D. R. (2023). Anterograde Amnesia due to Hippocampal Ischemia. [Context result 9] [10] Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR). [Context result 10] [11] Dissociative Fugue: A Rare Phenomenon in Dissociative Amnesia. [Context result 11]

Additional Differential Diagnoses

Additional Information

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