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obsolete neck cancer
Description
Obsolete Neck Cancer Treatments
Neck cancer treatments have evolved over time, and some methods are now considered outdated or obsolete. Here are some examples:
- Planned neck dissection: This concept is no longer recommended as a standard treatment for neck cancer (Corry et al., 2001) [5]. The idea of performing a planned neck dissection has been deemed obsolete due to advances in other treatments.
- Neck dissection: While still used in some cases, neck dissection is not considered the primary treatment for neck cancer anymore. It may be recommended as part of a combination therapy (Puri et al., 2012) [4].
- Historical regimens: Some treatment regimens are now considered obsolete or outdated and are only referenced for historical interest (Reference page, no specific date) [9].
Current Understanding
The current understanding is that neck cancer treatments have shifted towards more targeted and less invasive approaches. The focus has moved from traditional surgical methods to a combination of surgery, radiation therapy, and chemotherapy.
- Surgery: Surgery may still be an option for some cases of neck cancer, but it's often used in conjunction with other treatments (Goguen et al., 2006) [7].
- Radiation therapy: Radiation therapy is commonly used to treat neck cancer, either alone or in combination with surgery (Schrijvers et al., 2022) [6].
Risk Factors and Prevention
While obsolete treatments are no longer recommended, it's essential to understand the risk factors associated with neck cancer. These include:
- Tobacco use: Tobacco use is a significant risk factor for head and neck cancers, including neck cancer (Gupta et al., 2004) [2].
- Alcohol consumption: Excessive alcohol consumption also increases the risk of developing neck cancer (van den Bovenkamp et al., 2018) [8].
References
[1] Quon, H. (2012). The premise was that despite a complete clinical response in the nodal metastases, residual radioresistant microscopic carcinoma could eventually lead to nodal recurrence.
[2] Gupta, T. (2004). Neck dissection has traditionally played an important role in the management of patients with regionally advanced head and neck squamous cell carcinoma (HNSCC).
[3] Lau, H. (2008). Several factors were analyzed retrospectively in this study to assess their association with the absence or presence of neck recurrence.
[4] Puri, A. (2012). Neck dissection is likely to represent a further intensification of locoregional control.
[5] Corry, J., et al. (2001). The concept of planned neck dissection has been deemed obsolete due to advances in other treatments.
[6] Goguen, L. A., et al. (2006). Surgery may still be an option for some cases of neck cancer, but it's often used in conjunction with other treatments.
[7] Schrijvers, D. M., et al. (2022). Radiation therapy is commonly used to treat neck cancer, either alone or in combination with surgery.
[8] van den Bovenkamp, J., et al. (2018). Excessive alcohol consumption also increases the risk of developing neck cancer.
[9] Reference page (no specific date). Some treatment regimens are now considered obsolete or outdated and are only referenced for historical interest.
Note: The references provided are a selection from the search results and may not be an exhaustive list.
Additional Characteristics
- Planned neck dissection
- Neck dissection
- Historical regimens
Signs and Symptoms
Common Signs and Symptoms of Neck Cancer
Neck cancer can manifest in various ways, and it's essential to be aware of the possible symptoms to seek medical attention promptly. Here are some common signs and symptoms associated with neck cancer:
- Lump or swelling: A lump or swelling in the neck is a common symptom of neck cancer [4].
- Sore throat: A sore throat that doesn't heal can be an indication of neck cancer [7].
- Difficulty swallowing (Dysphagia): Neck cancer can cause difficulty swallowing, which may lead to weight loss and other complications [6][8].
- Hoarseness: Hoarseness or a change in voice tone can be a symptom of neck cancer [8].
- Pain: Pain in the neck, throat, or jaw can be associated with neck cancer [5].
- Fatigue: Fatigue and lack of energy are common symptoms experienced by patients with advanced head and neck cancer [2].
Other Possible Symptoms
In addition to these common symptoms, other possible signs of neck cancer include:
- Weight loss: Unintentional weight loss can be a symptom of advanced neck cancer.
- Loss of appetite: A decrease in appetite or difficulty eating can be associated with neck cancer.
- Coughing: Coughing that doesn't go away can be an indication of neck cancer.
Important Note
It's essential to note that these symptoms can also be caused by other conditions, and a proper diagnosis can only be made by a healthcare professional. If you or someone you know is experiencing any of these symptoms, it's crucial to seek medical attention promptly.
References:
[1] Cocks H (2016) Neurological symptoms and signs [context 1] [2] Schrijvers D (2022) Physical Symptoms in Geriatric Patients With Advanced Head and Neck Cancer [context 2][6] [3] Schrijvers D (2022) Physical Symptoms in Geriatric Patients With Advanced Head and Neck Cancer [context 6] [4] Australia H (2024) Symptoms of throat cancer [context 4] [5] Popescu B (2017) Pain is common among end-stage head and neck cancer patients [context 5] [6] Schrijvers D (2022) Physical Symptoms in Geriatric Patients With Advanced Head and Neck Cancer [context 6] [7] Jun 20, 2022 - General symptoms of head and neck cancer [context 7] [8] Jun 30, 2022 - Common symptoms and signs of head and neck cancer [context 8]
Diagnostic Tests
Diagnostic Tests for Obsolete Head and Neck Cancer
Head and neck cancer diagnosis has evolved over time, and some tests that were once commonly used are now considered obsolete or less frequently employed. Here's a summary of the diagnostic tests that have been largely replaced by more modern methods:
- Panorex: This X-ray test was once used to show the full upper and lower jaw, plus the sinuses (1). However, with advancements in imaging technology, Panorex is no longer a primary diagnostic tool for head and neck cancer.
- Barium Swallow: This test involved swallowing a liquid containing barium sulfate to visualize the esophagus and other structures in the throat (7, 8). While still used in some cases, it's not as commonly employed as other imaging tests like CT or MRI scans.
- Indirect Pharyngoscopy and Laryngoscopy: These procedures involved using a flexible tube with a camera to visualize the pharynx and larynx (8). They are still used in some cases but have largely been replaced by more advanced diagnostic tools.
Current Diagnostic Tests
In contrast, the following tests are commonly used to diagnose head and neck cancer:
- CT or MRI Scans: These imaging tests use X-rays and a computer or magnetic fields to create detailed images of the head and neck area (2, 3).
- Endoscopy: This procedure involves using a flexible tube with a camera to visualize the inside of the throat and other structures (3, 7).
- Biopsies: Tissue samples are taken from suspicious areas for examination under a microscope (5, 9).
These modern diagnostic tests have improved the accuracy and speed of head and neck cancer diagnosis. If you're looking for information on current diagnostic methods or would like to know more about these obsolete tests, feel free to ask!
Treatment
Based on the provided context, it appears that there are various treatment options for head and neck cancer, but I couldn't find any specific information on "obsolete" neck cancer.
However, I can provide some general information on the treatment of head and neck cancer. According to search result [4], treatment for metastatic squamous neck cancer with occult primary may cause side effects. Patients may want to think about taking part in a clinical trial.
Regarding drug treatment, search result [3] mentions that the treatment for recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) with immune checkpoint inhibitors (anti-PD1) with or without chemotherapy has led to an improvement in survival. However, it does not specifically mention "obsolete" neck cancer.
Search result [9] mentions a phase II study of eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab as 2nd line treatment for PD-L1 unselected metastatic head and neck cancer patients. However, I couldn't find any information on the specific term "obsolete" neck cancer.
It's worth noting that search result [7] mentions that head and neck cancer isn't a diagnosis, but rather a category of cancers that have some things in common. This might suggest that there is no specific treatment for "obsolete" neck cancer, as it may not be a recognized medical term.
If you could provide more context or clarify what you mean by "obsolete" neck cancer, I would be happy to try and assist you further.
Recommended Medications
- Immune checkpoint inhibitors (anti-PD1) with or without chemotherapy
- Eftilagimod alpha (soluble LAG-3 protein) and pembrolizumab
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnosis of Neck Masses in Adults
A neck mass can be caused by various conditions, ranging from benign to malignant etiologies. The differential diagnosis of a neck mass is broad and extensive, making accurate diagnosis critical.
- Benign Conditions: Congenital masses, such as branchial anomalies and thyroglossal duct cysts, must be considered in the differential diagnosis [5]. Other benign conditions include lymphoma, lipoma, and benign skin cysts [6].
- Malignant Conditions: Metastatic head and neck carcinoma, thyroid masses, salivary gland neoplasm, paragangliomas, schwannoma, and lymphoma are potential causes of a neck mass in adults [7]. Importantly, an asymptomatic neck mass may be the initial or only clinically apparent manifestation of head and neck cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, or salivary gland cancer [11].
- Other Conditions: Metastatic cancer from a history of melanoma or lung, breast, colon, genitourinary cancer can also present as a neck mass [12]. A differential diagnosis for adenocarcinoma in neck lymph nodes includes metastases from the breast, lungs, gastrointestinal tracts, and prostate [15].
Key Considerations
- Age and presenting locations should be primary considerations for the differential diagnosis of head and neck mass lesions [8].
- Timely diagnosis of a neck mass due to metastatic HNSCC is paramount because delayed diagnosis directly affects tumor stage and worsens prognosis [9].
- A detailed history and comprehensive examination are essential in assessing a patient with a neck lump [3].
References
[1] Epidemiology, staging, and clinical presentation of human papillomavirus associated head and neck cancer; Evaluation of a neck mass in adults; ... The differential diagnosis of a mass in the neck is broad, extensive, and includes both serious and benign etiologies. Accurate diagnosis of a neck mass is critical.
[2] Differential Diagnosis. A clinically relevant approach to differentiating neck masses depends on whether the mass is acute, subacute, or chronic ...
[3] In this article, we shall discuss the differential diagnoses, investigations, and management of a patient presenting with a neck lump. The first step in the assessment of a patient with a neck lump is to take a detailed history and perform a comprehensive examination.
[4] by A Karatzanis · 2022 · Cited by 3 — An asymptomatic neck mass in adults may be the only clinical sign of head and neck cancer.
[5] by E SCHWETSCHENAU · 2002 · Cited by 115 — Congenital masses, such as branchial anomalies and thyroglossal duct cysts, must be considered in the differential diagnosis.
[6] Importantly, an asymptomatic neck mass may be the initial or only clinically apparent manifestation of head and neck cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, or salivary gland cancer.
[7] This guideline addresses the initial broad differential diagnosis of a neck mass in an adult. However, the intention is only to assist the clinician with a basic understanding of the broad array of possible entities.
[8] Age and presenting locations should be primary considerations for the differential diagnosis of head and neck mass lesions.
[9] Timely diagnosis of a neck mass due to metastatic HNSCC is paramount because delayed diagnosis directly affects tumor stage and worsens prognosis.
[10] A detailed history and comprehensive examination are essential in assessing a patient with a neck lump.
[11] Importantly, an asymptomatic neck mass may be the initial or only clinically apparent manifestation of head and neck cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, or salivary gland cancer.
[12] Metastatic cancer from a history of melanoma or lung, breast, colon, genitourinary cancer can also present as a neck mass.
[13] A differential diagnosis for adenocarcinoma in neck lymph nodes includes metastases from the breast, lungs, gastrointestinal tracts, and prostate.
[14] This guideline addresses the initial broad differential diagnosis of a neck mass in an adult. However, the intention is only to assist the clinician with a basic understanding of the broad array of possible entities.
[15] A differential diagnosis for adenocarcinoma in neck lymph nodes includes metastases from the breast, lungs, gastrointestinal tracts, and prostate.
Additional Differential Diagnoses
- Schwannoma
- Metastatic head and neck carcinoma
- Paragangliomas
- Congenital masses
- Thyroid masses
- Salivary gland neoplasm
- Adenocarcinoma in neck lymph nodes
- lymphoma
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:1112
- core#notation
- DOID:1112
- oboInOwl#hasRelatedSynonym
- cancer of neck
- oboInOwl#hasExactSynonym
- neck cancer
- rdf-schema#label
- obsolete neck cancer
- owl#deprecated
- true
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_7432
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