obsolete Iris and ciliary body vascular disorder

Iris and Ciliary Body Vascular Disorder (193501009)

The term "Iris and ciliary body vascular disorder" is an outdated medical descriptor that was used to describe a condition affecting the iris and ciliary body in the eye. This condition is now referred to by more specific terms, such as uveitis or neovascular glaucoma.

Historical Context

In the past, this term was used to describe a disorder of the vascular layer of the eye, specifically involving the iris and ciliary body. However, with advancements in medical knowledge and terminology, this descriptor has become obsolete.

Current Understanding

The current understanding of similar conditions, such as uveitis or neovascular glaucoma, involves inflammation or ischemia affecting the uveal tract, which includes the iris, ciliary body, and choroid (see [6], [7], [8]). These conditions can be caused by various factors, including infections, autoimmune disorders, or systemic vascular diseases.

Relevance to Modern Medicine

While the term "Iris and ciliary body vascular disorder" is no longer used in modern medical practice, its historical significance lies in the understanding of similar conditions that affect the eye's uveal tract. The knowledge gained from studying these conditions has contributed to the development of more accurate and specific diagnoses, such as uveitis or neovascular glaucoma.

References

• [3] UGH syndrome results from an IOL chafing the iris, iridocorneal angle, or ciliary body, which leads to recurrent trauma to these structures.
• [5] Neovascular glaucoma is a severe form of glaucoma that occurs as a result of vascular ischemia in various diseases, leading to the closure of the angle in the ...
• [6] Oct 10, 2024 — The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its ...
• [7] Uveitis is a broad term for inflammation of one or all parts of the uvea, or the vascular area between the retina and sclera of the eye.
• [8] Inflammation of the uvea, which is the vascular layer of the eye, is termed uveítis. Uveítis may be caused by infections, autoimmune disorders, or secondary ...

Based on the provided context, it appears that there are several conditions related to the iris and ciliary body that may be considered obsolete or outdated. However, I will provide information on some signs and symptoms associated with these conditions.

Anterior Uveitis

• Eye pain [11]
• Red eye or eye irritation [11]
• Blurred vision [11]
• Light sensitivity (photophobia) [11]
• Swollen conjunctiva [11]
• Pupil shape changes (from a circle to an irregular shape) [11]

Iritis

• Pain in the eye [9]
• Photophobia [9]
• Tearing [9]
• Blurred vision [9]

Uveitis

• May be asymptomatic; severe uveitis with sudden onset may cause any of the following:
  • Blurring of vision [15]
  • Redness [15]
  • Sensitivity to light [15]
  • Aching in the affected eye or eyes [15]

Please note that these symptoms are associated with conditions that affect the iris and ciliary body, but it's essential to consult a medical professional for accurate diagnosis and treatment.

References: [9] - Iritis has a rapid onset and typically affects only one eye. Signs and symptoms of irtis include pain in the eye, photophobia, tearing, and blurred vision. [11] - The symptoms of anterior uveitis include: Eye pain. Red eye or eye irritation. Blurred vision. Light sensitivity (photophobia). Swollen conjunctiva. Pupil shape changes (from a circle to an irregular shape). [15] - May be asymptomatic; severe uveitis with sudden onset may cause any of the following: blurring of vision, redness, sensitivity to light, and aching in the affected eye or eyes.

Based on the provided context, it appears that there are several diagnostic tests that can be used to diagnose iris and ciliary body vascular disorders.

• Ultrasound Biomicroscopy (UBM): This imaging test uses high-energy sound waves to create an image of the internal tissues of the eye. It has been proven useful in the diagnosis and management of anterior segment pathology, including iris and ciliary body vascular disorders [6].
• Optical Coherence Tomography (OCT): This imaging technique can also be used to assess the structure of the iris and ciliary body. It is a non-invasive test that uses low-coherence interferometry to produce high-resolution images of the eye's internal structures [5].
• Slit Lamp Examination: A thorough slit lamp examination can reveal tortuous, dilated vascular loops running from the iris root to the peripupillary region and back. This can be a sign of an iris and ciliary body vascular disorder [4].
• High-Frequency Ultrasound Biomicroscopy (UBM): This test has been used to diagnose anterior segment pathology, including iris and ciliary body vascular disorders. It is a non-invasive test that uses high-frequency sound waves to create detailed images of the eye's internal structures [6].

It's worth noting that these diagnostic tests may not be specific to obsolete iris and ciliary body vascular disorder, but rather can be used to diagnose various conditions affecting the anterior segment of the eye.

References: [4] - A tortuous, dilated vascular loop running from iris root to peripupillary region and back is a sign of an iris and ciliary body vascular disorder. [5] - Optical Coherence Tomography (OCT) can be used to assess the structure of the iris and ciliary body. [6] - High-frequency ultrasound biomicroscopy (UBM) has been proven useful in the diagnosis and management of anterior segment pathology, including iris and ciliary body vascular disorders.

Based on the provided context, it appears that there are various treatment options for iris and ciliary body vascular disorders, but some may be considered obsolete.

• Miotics: Miotics can be used to treat pigmentary glaucoma by constricting the pupil and preventing the iris from rubbing against the lens [6]. However, this treatment option may not directly address the vascular disorder.
• Bevacizumab: Bevacizumab has been used in combination with other treatments for neovascular glaucoma, but its use as a standalone treatment for iris and ciliary body vascular disorders is unclear [9].
• Dexamethasone intraocular implant: This treatment option can raise pressure inside the eye and may not be suitable for all patients [3].

It's essential to note that these treatment options might not be considered obsolete, but rather, they might have specific indications or limitations. The most effective treatment approach would depend on individual patient factors and the severity of the condition.

In contrast, some treatments mentioned in the context are more contemporary:

• Ranibizumab: This medication is used to treat exudative and vasogenic chorioretinal diseases, including variants of age-related macular degeneration (AMD) [2].
• Vitrectomy with ciliary body suturing: This surgical procedure may be considered for treating certain types of uveitis or vascular disorders affecting the iris and ciliary body [4].

It's crucial to consult up-to-date medical literature and expert opinions for the most accurate and effective treatment recommendations.

The differential diagnosis for an obsolete iris and ciliary body vascular disorder can be complex, involving various conditions that affect the eye's anterior segment.

According to medical literature [1], acquired ectropion uveae (AEU), also known as acquired iris ectropion, is a condition where the iris becomes detached from its normal position. This can be caused by various factors, including inflammation, trauma, or systemic diseases.

In terms of differential diagnosis, AEU should be considered in cases where there are symptoms or signs of a systemic disorder [2]. Other conditions that may present similarly include:

• Iridoschisis: a rare condition characterized by the separation of the anterior iris stroma from the posterior stroma and muscle layers [3].
• Iridocyclitis: inflammation of the iris and ciliary body, which can be caused by a postinfectious condition [7].
• Neovascular glaucoma: a severe form of glaucoma that occurs as a result of vascular ischemia in various diseases, leading to the closure of the angle in the eye [9].

It's also worth noting that certain systemic conditions, such as collagen vascular disorders, can cause severe ocular morbidity and should be considered in the differential diagnosis [12]. Additionally, tumors or cysts affecting the iris and ciliary body may also present with similar symptoms.

In cases where the clinical presentation is unclear, diagnostic testing may be necessary to determine the underlying cause of the condition. This can include imaging studies, such as ultrasound or MRI, as well as laboratory tests to rule out systemic diseases [10].

References:

[1] Disease Entity: Acquired ectropion uveae (AEU), also known as acquired iris ectropion.

[2] Context 2

[3] Context 3

[7] Context 7

[9] Context 9

[12] Context 12