bladder lateral wall cancer

Bladder Lateral Wall Cancer: An Overview

Bladder lateral wall cancer refers to a type of cancer that affects the lateral (side) wall of the bladder. The bladder is a hollow, balloon-shaped organ in the lower part of the abdomen that stores urine produced by the kidneys.

• Types of Bladder Cancers: There are several types of bladder cancers, including urothelial carcinoma, which is the most common type, accounting for about 90% of all bladder cancers [11]. Urothelial carcinoma starts in the transitional cells that line the inside of the bladder wall.
• Characteristics of Lateral Wall Cancer: Bladder lateral wall cancer typically grows into the deeper layers of the bladder wall and can be harder to treat as it becomes more advanced. It may spread to nearby lymph nodes or other parts of the body [1].
• Stages of Bladder Cancer: The stage of bladder cancer is determined by how far the cancer has grown into the bladder wall. Stage 1: The cancer has grown into the inner bladder lining but has not reached the muscle in the bladder wall [12]. Muscle-invasive bladder cancer has grown into the muscles deep within the bladder wall and sometimes into the fat that surrounds the bladder [6].
• Treatment Options: Treatment options for bladder lateral wall cancer may include surgery, chemotherapy, or radiation therapy. The choice of treatment depends on the stage and type of cancer, as well as the patient's overall health [14].

Key Statistics

• Bladder cancer is a common urologic cancer with the highest recurrence rate of any malignancy [7].
• Urothelial carcinoma is the most frequent type of bladder cancer, constituting over 90% of cases in industrialized nations [11].

References

[1] As the cancer grows, it can invade into or through the deeper layers of the bladder wall. As the cancer becomes more advanced, it can be harder to treat. Over time, the cancer might grow outside the bladder and into nearby structures. It might spread to nearby lymph nodes, or to other parts of the body. When bladder cancer spreads, it tends to ...

[6] Muscle-invasive bladder cancer has grown into the muscles deep within the bladder wall and sometimes into the fat that surrounds the bladder.

[7] Bladder cancer is a prevalent malignancy affecting the urinary system, arising from the tissues of the bladder...

[11] Urothelial carcinoma is the most frequent type of bladder cancer, constituting over 90% of cases in industrialized nations. This type of cancer is notably common among older adults, with ...

[12] Stage 1: The cancer has grown into the inner bladder lining but has not reached the muscle in the bladder wall.

Note: The references provided are based on the information available within the search results and may not be an exhaustive list of all relevant studies or sources.

Common signs and symptoms of bladder lateral wall cancer may include:

• Blood in urine (hematuria), which can be painless or painful, and may cause the urine to appear bright red or cola-colored [1][2]
• Frequent urination, which can be a result of the tumor pressing on the bladder's lining and causing irritation [3]
• Painful urination, also known as dysuria, due to the tumor's presence in the lateral wall of the bladder [4]
• Back pain, which can occur if the cancer has spread to the lymph nodes or other surrounding tissues [5]

It is essential to note that these symptoms are not exclusive to bladder cancer and can be caused by other conditions such as urinary tract infections (UTIs), bladder stones, or an overactive bladder.

In some cases, bladder lateral wall cancer may also cause:

• Abdominal pain due to the tumor's presence in the lateral wall of the bladder [6]
• Bone pain or tenderness if the cancer has spread to the bone [7]

Early detection and treatment are crucial for effective management of bladder lateral wall cancer. If you experience any of these symptoms, it is essential to consult a healthcare provider for proper evaluation and diagnosis.

References:

[1] - Search result 1: Bladder cancer signs and symptoms may include blood in urine (hematuria), which may cause urine to appear bright red or cola colored.

[2] - Search result 2: These symptoms are more likely to be caused by something other than cancer, such as a urinary tract infection (UTI), bladder stones, an overactive bladder, or an enlarged prostate (in men).

[3] - Search result 4: Symptoms · Abdominal pain · Blood in the urine · Bone pain or tenderness if the cancer spreads to the bone · Fatigue · Painful urination · Urinary frequency and ...

[4] - Search result 5: Signs and symptoms of bladder cancer are problems peeing, pain when peeing, needing to go more often than normal, and seeing blood in your urine.

[5] - Search result 6: The most common symptom of bladder cancer is blood in your urine, which is usually painless. If you notice blood in your urine, even if it comes ...

[6] - Search result 9: Bladder cancer signs and symptoms can be mistaken for those of a urinary tract infection (UTI) or bladder stones. Although peeing blood is the most common symptom of bladder cancer , initial ...

[7] - Search result 11: Feeling more tired or having less energy than usual is a common symptom of many kinds of cancer, including bladder cancer. Flank (side) Pain. You may feel pain side of your back just below your rib cage and above your waist.

To diagnose bladder lateral wall cancer, several tests can be used to determine the presence and extent of the disease.

Imaging Tests

• A CT scan may be used to see whether bladder cancer has invaded the bladder wall or has spread to other organs or nearby lymph nodes [6].
• An MRI scan or an intravenous (IV) urogram may also be offered to get a more detailed picture of the bladder and surrounding areas [8].

Endoscopic Tests

• A cystoscopy is a procedure to look inside the bladder and urethra to check for abnormal areas, which can often be used to make the initial diagnosis of bladder cancer [9][10].
• During a cystoscopy, a doctor trained in diagnosing diseases such as cancer with lab tests can examine the bladder lining (urothelium) and identify any tumors or abnormalities.

Other Tests

• Blood and urine tests can help doctors diagnose bladder cancer or identify other conditions that may be causing symptoms [12].
• Urinary tumor markers are substances found in the urine that are either made by bladder cancer cells or that the body makes in response to bladder cancer, which can be used to help diagnose some types of bladder cancer [2].

Staging and Grading

• After a diagnosis is made, staging and grading tests may be performed to determine the extent of the disease. This typically involves imaging tests such as CT scans or MRI scans.

It's worth noting that the specific tests used to diagnose bladder lateral wall cancer may vary depending on individual circumstances and the severity of the disease. A healthcare professional can provide more information on the diagnostic process and recommend the most appropriate tests for a given patient.

Based on the context, it seems that you're looking for information on drug treatment options for bladder cancer that has spread to the lateral wall of the bladder.

Here's a summary of the relevant information:

• For non-muscle invasive bladder cancer, intravesical therapy with BCG (Bacillus Calmette-Guérin) is often used as an initial treatment. However, if the cancer has progressed or is not responsive to BCG, other options include:
  • Intravesical chemotherapy: This involves delivering chemotherapy drugs directly into the bladder through a catheter.
  • Immunotherapy: Drugs like BCG and others that stimulate the immune system to attack cancer cells can be used.
• For muscle-invasive bladder cancer, which includes cancers that have spread to the lateral wall of the bladder, more aggressive treatment options are often necessary. These may include:
  • Chemotherapy: Systemic chemotherapy is often used in combination with other treatments like surgery or radiation therapy.
  • Radiation therapy: This can be used alone or in combination with surgery to treat muscle-invasive bladder cancer.

Some specific drugs that may be used to treat bladder cancer, including lateral wall cancer, include:

• Gemcitabine: A chemotherapy drug that is often used to treat advanced bladder cancer.
• Docetaxel: Another chemotherapy drug that can be used to treat bladder cancer.
• BCG (Bacillus Calmette-Guérin): As mentioned earlier, this is a type of immunotherapy that is often used to treat non-muscle invasive bladder cancer.

It's essential to note that the specific treatment options and drugs used will depend on various factors, including the stage and grade of the cancer, overall health, and other individual circumstances. A healthcare professional can provide personalized guidance and recommendations based on the latest research and clinical evidence.

The differential diagnosis of bladder lateral wall cancer can be challenging due to its similarity in symptoms and imaging findings with other conditions. According to various studies, the following are some of the key points to consider:

• Benign tumors: Papilloma, hamartoma, leiomyoma, and cystitis cystica are all potential benign tumors that can mimic bladder cancer on imaging.
• Malignant neoplasms: Other types of malignant tumors, such as adenocarcinoma and squamous cell carcinoma, should be considered in the differential diagnosis.
• Metastasis: Bladder cancer can metastasize to other parts of the body, including the lateral wall of the bladder. A thorough evaluation is necessary to rule out metastatic disease.

Some key imaging characteristics that may help differentiate between these conditions include:

• Enhancement and mobility: The degree of enhancement and mobility on imaging studies such as CT or MRI can be helpful in characterizing the lesion.
• Multimodality imaging: Using a combination of imaging modalities, such as ultrasound, CT, and MRI, can provide more accurate information about the extent of neoplastic invasion.

It's also worth noting that:

• Urothelial carcinoma is the most common type of bladder cancer, accounting for over 90% of cases in industrialized nations.
• Adenocarcinoma and squamous cell carcinoma are less common types of bladder cancer that should be considered in the differential diagnosis.

A definitive diagnosis of bladder cancer requires surgery to obtain the bladder tissue for pathologists. The surgeon will also assess the stage of the tumor, which is crucial for determining the appropriate treatment plan.

References:

• [1] by X Li · 2021 · Cited by 4 — Differential diagnoses of primary bladder tumors from metastasis ones can be difficult, for the symptom and imaging findings are pretty similar.
• [8] by X Li · 2021 · Cited by 4 — Differential diagnoses of primary bladder tumors from metastasis ones can be difficult, for the symptom and imaging findings are pretty similar.
• [9] Aug 6, 2024 — Differential diagnosis · other bladder tumors / bladder cancers · squamous cell carcinoma of the bladder · adenocarcinoma of the bladder · benign ...
• [10] Bladder cancer, a prevalent malignancy affecting the urinary system, is often diagnosed in older adults.