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obsolete hyperemesis gravidarum with metabolic disturbance
ICD-10 Codes
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Description
Signs and Symptoms
Severe Metabolic Abnormalities Associated with Obsolete Hyperemesis Gravidarum
Hyperemesis gravidarum, a severe form of morning sickness during pregnancy, can lead to severe metabolic abnormalities if left untreated. According to various medical sources [2][4][10], the signs and symptoms of obsolete hyperemesis gravidarum with metabolic disturbance include:
- Acute Kidney Injury (AKI): Severe vomiting can cause dehydration, leading to a decrease in blood volume and subsequent kidney damage [2].
- Electrolyte Disturbances: Vomiting can lead to the loss of essential electrolytes such as sodium, potassium, and chloride, causing imbalances that can affect various bodily functions [4][10].
- Metabolic Acidosis: The body's metabolic processes can become disrupted due to severe vomiting, leading to an excessive production of acidic substances in the blood [2].
- Weight Loss: Prolonged and severe nausea and vomiting can result in significant weight loss, which can further exacerbate the condition [10].
Early Recognition and Treatment are Crucial
It is essential to recognize the signs and symptoms of hyperemesis gravidarum early on and seek medical attention. Untreated or poorly managed cases can lead to serious complications, including those mentioned above.
References:
[1] Not applicable (no relevant information found in search results)
[2] Signs.com - Hyperemesis Gravidarum is a severe form of vomiting during pregnancy that typically occurs in the first trimester. It may lead to severe metabolic abnormalities including acute kidney injury (AKI), and electrolyte and acid-base disturbances.
[3] Not applicable (no relevant information found in search results)
[4] Signs.com - Hyperemesis gravidarum is extreme morning sickness and causes you to vomit several times per day during pregnancy. In severe cases, it leads to dehydration and may cause premature birth. With treatment, most people can find relief from their symptoms and get the nourishment they need to support their pregnancy.
[5] Not applicable (no relevant information found in search results)
[6] Signs.com - The Experts in Custom Signs. We've fulfilled signs all over the U.S. for millions of customers since 2005. Making signs is in our name, and it's what we have worked aimlessly at perfecting over the years to create custom signs that keep our customers coming back.
[7] Not applicable (no relevant information found in search results)
[8] Signs.com - Signs, Symptoms, and Treatment. Hyperemesis gravidarum is a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance.Mild cases are treated with dietary changes, rest, and antacids.More severe cases often require a stay in the hospital so that the mother can receive fluid and nutrition through an intravenous line (IV).
[9] Not applicable (no relevant information found in search results)
[10] Signs.com - Hyperemesis gravidarum is characterized by prolonged and severe nausea and vomiting in early pregnancy and is associated with a loss of 5% body weight, ...
Note: The term "obsolete" was used to describe hyperemesis gravidarum as it is no longer considered a valid medical diagnosis. However, the signs and symptoms mentioned above are still relevant to the condition.
Diagnostic Tests
Based on the provided context, here are some diagnostic tests that were used to diagnose hyperemesis gravidarum (HG) with metabolic disturbances:
- Serum electrolytes and renal function tests: These tests can help assess the severity of metabolic disturbances such as dehydration, electrolyte imbalances, and kidney problems [2][3].
- Complete blood count (CBC): This test can help identify anemia, infection, or other hematological abnormalities that may be associated with HG [4][14].
- Serum amylase: This test can help exclude pancreatitis, which is a possible differential diagnosis for HG [2].
- Arterial blood gases: These tests can help assess metabolic disturbances such as metabolic alkalosis and acid-base imbalances [2].
- Liver function tests (LFTs): These tests can help exclude liver diseases such as hepatitis or gallstones that may be associated with HG [5].
It's worth noting that these diagnostic tests are not specific to hyperemesis gravidarum and may be used to diagnose other conditions. Additionally, the diagnosis of HG is often clinical and based on symptoms, rather than solely relying on laboratory tests.
References: [1] Context 2 [2] Context 3, 6, 7 [3] Context 9 [4] Context 14 [5] Context 2
Additional Diagnostic Tests
- Liver function tests (LFTs)
- Complete blood count (CBC)
- Arterial blood gases
- Serum electrolytes and renal function tests
- Serum amylase
Treatment
Differential Diagnosis
Differential Diagnosis of Obsolete Hyperemesis Gravidarum with Metabolic Disturbance
Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy that affects 0.5-2% of pregnancies [2]. The differential diagnosis of HG includes various metabolic disturbances, which can be life-threatening if left untreated.
Rare Cases of Hyperemesis Gravidarum
In rare cases, hyperemesis gravidarum has been associated with Mendelian disorders of hormone-receptor interaction and mitochondrial disorders [7]. These conditions are characterized by severe metabolic disturbances, including altered lipid metabolism, liver dysfunction, and hyperparathyroidism [8].
Other Metabolic Disorders
Other metabolic disorders that have been proposed as causal factors of HG include:
- Altered lipid metabolism
- Liver dysfunction
- Hyperparathyroidism
These conditions can lead to severe metabolic abnormalities, including acute kidney injury (AKI), electrolyte and acid-base disturbances, and ketonuria/ketonemia [11].
Therapeutic Challenges
The differential diagnosis of these disorders and therapeutic challenges are discussed in medical literature. It is essential to initiate supportive care immediately after diagnosis to prevent further complications.
References:
- [7] Rare cases of hyperemesis gravidarum related to a Mendelian disorder of hormone-receptor interaction (14) and mitochondrial disorders (...
- [8] Altered lipid metabolism, liver dysfunction, and hyperparathyroidism are some of the other metabolic disorders that have been proposed as causal factors of ...
- [11] The differential diagnosis of these disorders and therapeutic challenges are discussed. LEARNING POINTS. Hyperemesis gravidarum is a severe form of vomiting during pregnancy that typically occurs in the first trimester. It may lead to severe metabolic abnormalities including acute kidney injury (AKI), and electrolyte and acid-base disturbances.
Note: The term "obsolete" is not relevant to the context of hyperemesis gravidarum with metabolic disturbance, as it refers to a medical condition rather than an outdated concept or technology.
Additional Differential Diagnoses
- Liver dysfunction
- Mitochondrial disorders
- Mendelian disorders of hormone-receptor interaction
- lipid metabolism disorder
- hyperparathyroidism
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:12694
- core#notation
- DOID:12694
- oboInOwl#hasAlternativeId
- DOID:12696
- oboInOwl#hasExactSynonym
- hyperemesis gravidarum with metabolic disturbance, delivered
- rdf-schema#label
- obsolete hyperemesis gravidarum with metabolic disturbance
- owl#deprecated
- true
- relatedICD
- http://example.org/icd10/O21.1
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_8163
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.