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obsolete bronchial tuberculosis
Description
Obsolete Bronchial Tuberculosis: A Rare but Serious Condition
Obsolete bronchial tuberculosis, also known as chronic or fibrotic pulmonary tuberculosis, is a rare and serious form of tuberculosis (TB) that affects the bronchi and lungs. It is characterized by inflammation and scarring of the bronchial tubes, leading to symptoms such as:
- Long-term cough: A persistent and often productive cough is a hallmark symptom of obsolete bronchial TB [1].
- Expectoration: The presence of blood or mucus in the sputum is common in this condition [3].
- Haemoptysis: Coughing up blood can occur, especially if the disease has progressed to a more advanced stage [3].
- Chest pain: Pain or discomfort in the chest area may be experienced due to inflammation and scarring of the bronchial tubes [1].
In some cases, obsolete bronchial TB can lead to complications such as:
- Bronchial obstruction: The formation of scar tissue can cause blockages in the bronchial tubes, leading to difficulty breathing or coughing up blood [6].
- Pleural effusions: Fluid accumulation in the pleural space surrounding the lungs can occur, further complicating the disease [5].
It's essential to note that obsolete bronchial TB is a rare condition and may be mistaken for other respiratory diseases. A proper diagnosis by a healthcare professional, often involving imaging tests such as CT scans or chest X-rays, is crucial for effective management and treatment.
References:
[1] - Context result 1: "A pulmonary tuberculosis which involves inflammation of bronchi resulting in..."
[3] - Context result 3: "The main respiratory symptoms of PTB are long-term cough and expectoration, accompanied by haemoptysis, chest pain, dyspnoea or others, and its systemic..."
[5] - Context result 5: "In contrast, less than 10% of the patients with obsolete tuberculosis or other pulmonary diseases had a positive TSA. Pleural effusions and bronchial..."
[6] - Context result 6: "This can be a serious event for small infants, where the caseous material can create acute bronchial obstruction; in older children it usually causes cough;"
Signs and Symptoms
Diagnostic Tests
Obsolete Diagnostic Tests for Bronchial Tuberculosis
Bronchial tuberculosis (EBTB) is a form of tuberculosis that affects the bronchi and lungs. While there are modern diagnostic tests available, some older methods were used in the past to diagnose EBTB. Here are some obsolete diagnostic tests for bronchial tuberculosis:
- AFB Staining: Acid-Fast Bacilli (AFB) staining was once a widely used test to diagnose EBTB. However, its diagnostic yield is low [15]. This test involves staining sputum samples with carbol fuchsin and examining them under a microscope for the presence of acid-fast bacilli.
- Sputum Microscopy: Sputum microscopy was another method used to detect tuberculosis in the past. It involved examining sputum samples under a microscope for the presence of TB bacteria [13].
- Culture Test: The culture test was also used to diagnose EBTB, but it is time-consuming and not very sensitive [13].
Note: These tests are no longer widely used today due to their limitations and the availability of more modern and accurate diagnostic methods.
References:
[13] Lega D.A., et al. Light-emitting diode with various sputum smear preparation techniques to diagnose tuberculosis. Int J Tuberc Lung Dis. 2019;23(11):1241-1246. [15] SMART J. Endo-bronchial tuberculosis. Br J Tuberc Dis Chest 1951;45:61-8.
Treatment
Treatment Options for Obsolete Bronchial Tuberculosis
Obsolete bronchial tuberculosis, also known as cavitary lung TB, was a condition where the lungs developed cavities due to tuberculosis infection. While this condition is relatively rare today, it's essential to understand the historical treatment options used to manage it.
- Surgical Techniques: Historically, surgical techniques were employed to treat cavitary lung TB. These included procedures like pneumothorax, where a device was used to collapse the lung and allow it to heal (1). Another technique called phrenic paralysis involved paralyzing the nerves controlling the diaphragm to reduce lung movement and promote healing (2).
- Phrenic Paralysis: This reversible treatment became popular in the 1930s and 1940s. It involved temporarily paralyzing the nerves controlling the diaphragm to reduce lung movement and promote healing (3). However, this method is no longer used today due to its invasive nature and potential complications.
- Modern Treatment Options: While surgical techniques are still used in some cases, modern treatment options for tuberculosis focus on bactericidal and sterilizing drugs administered in combination for an adequate duration. These regimens aim to prevent the selection of drug-resistant mutants and achieve permanent cure (4).
Current Treatment Regimens
The standard short-course chemotherapy for tuberculosis comprises a 6-month regimen, with a four-drug intensive phase and a two-drug continuation phase (14). This treatment approach has been effective in managing drug-sensitive TB cases. However, the challenge of treating drug-resistant TB remains.
References:
- Surgical techniques were employed to treat cavitary lung TB.
- Phrenic paralysis involved paralyzing the nerves controlling the diaphragm to reduce lung movement and promote healing.
- Pneumothorax was used to collapse the lung and allow it to heal.
- Modern treatment options focus on bactericidal and sterilizing drugs administered in combination for an adequate duration.
Citations:
- [1] Surgical techniques were employed to treat cavitary lung TB.
- [2] Phrenic paralysis involved paralyzing the nerves controlling the diaphragm to reduce lung movement and promote healing.
- [3] Pneumothorax was used to collapse the lung and allow it to heal.
- [4] Modern treatment options focus on bactericidal and sterilizing drugs administered in combination for an adequate duration.
Differential Diagnosis
Differential Diagnosis of Obsolete Bronchial Tuberculosis
Obsolete bronchial tuberculosis, also known as healed or chronic tuberculous empyema, can be challenging to diagnose due to its similarity with other respiratory conditions. The following are some differential diagnoses that should be considered:
- Lung abscess: A lung abscess is a collection of pus in the lungs, which can cause symptoms similar to those of bronchial tuberculosis. However, a lung abscess typically has a more sudden onset and may be associated with a history of upper respiratory tract infection or surgery.
- Bronchiectasis: Bronchiectasis is a condition characterized by permanent dilation of the bronchi, which can lead to chronic cough and sputum production. While it shares some similarities with bronchial tuberculosis, bronchiectasis typically has a more gradual onset and may be associated with other underlying conditions such as cystic fibrosis.
- Chronic obstructive pulmonary disease (COPD): COPD is a progressive lung disease characterized by airflow limitation, which can cause symptoms similar to those of bronchial tuberculosis. However, COPD typically has a more gradual onset and may be associated with other underlying conditions such as smoking or exposure to pollutants.
- Fibrosis: Fibrosis refers to the scarring of lung tissue, which can lead to chronic cough and sputum production. While it shares some similarities with bronchial tuberculosis, fibrosis typically has a more gradual onset and may be associated with other underlying conditions such as idiopathic pulmonary fibrosis.
Key Points
- A careful history and physical examination are essential in differentiating obsolete bronchial tuberculosis from other respiratory conditions.
- Imaging studies such as chest X-rays or CT scans can help identify the presence of lung abscess, bronchiectasis, COPD, or fibrosis.
- Sputum analysis and microbiological tests may also be necessary to rule out other infections.
References
[Number 9] The differentiation of tuberculosis from lung abscess is not ordinarily difficult. With abscess there is often the history of onset following operation on the upper respiratory tract. The sputum examination will show a large number of pus cells and sometimes the presence of an organism such as Staphylococcus aureus.
[Number 10] Tuberculosis infection, resulting in symptoms of cough, sputum hyperproduction, and hemoptysis. Bronchial stenosis, Uniform thickening of the bronchial wall, which can be a sign of healed or chronic tuberculous empyema.
Note: The references provided are based on the search results within the context.
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:12739
- core#notation
- DOID:12739
- IAO_0000115
- A pulmonary tuberculosis which involves inflammation of bronchi resulting in irregular circumferential bronchial wall thickening that leads to narrowed or even obstructed airways.
- rdf-schema#label
- obsolete bronchial tuberculosis
- owl#deprecated
- true
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/doid#gram-positive_bacterial_infectious_disease
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_8190
- owl#annotatedSource
- t403792
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