obsolete female genitalia nevus

Obsolete Female Genitalia Nevus

A female genitalia nevus, also known as a vulvar nevus, is a rare type of birthmark that affects the skin in the genital area. It is characterized by a benign growth or lesion on the vulva, which can be present at birth or develop later in life.

Key Features:

• Benign growth or lesion on the vulva
• Can be present at birth or develop later in life
• Rare type of birthmark

According to search results [8], a female genitalia nevus is an obsolete term, suggesting that it may no longer be used in modern medical practice. However, the condition itself still exists and can be identified through various clinical features.

References:

[8] - This information is based on the description of "female genitalia nevus" provided in search results [8].

Common Signs and Symptoms

The signs and symptoms of vulvovaginal candidosis, a condition affecting the female genital area, can be quite distressing. According to various medical sources [3][4], patients with this condition typically report:

• Pre-menstrual itching, redness, and burning sensations in the introitus (the opening of the vagina) and vagina
• Dysuria (painful urination)
• Vulvar pain that may be incapacitating

In some cases, vulvovaginal candidosis can lead to more severe symptoms such as fissures, erosions, vulvar and perianal bruising [4]. These symptoms can sometimes be mistaken for signs of sexual abuse.

Other Possible Symptoms

Additionally, other conditions affecting the female genital area may present with different symptoms. For example:

• Genital erythema (redness) is a common sign in girls with vulvovaginitis, occurring in more than 80% of cases [6]
• Visible discharge is present in about one-third of cases [6]

Important Considerations

It's also worth noting that other conditions such as melanoma or basal cell carcinoma (BCC) can affect the female genital area. Melanoma may arise from a lesion containing a junctional or compound nevus, and pigmented lesions on the vulva should be considered suspicious if they are atypical [8]. BCCs typically appear as pearly papules with telangiectasias, often occurring on sun-exposed sites [9].

Common Characteristics of Benign Nevi

On the other hand, benign nevi (moles) may have distinct characteristics. They can be flat, elevated, or pedunculated, and their borders are usually sharp [10]. The diameter of most common nevi ranges from 3 to 10 mm.

Please note that these symptoms and signs should not be self-diagnosed, but rather consulted with a medical professional for proper evaluation and treatment.

Based on the provided context, it appears that there are limited treatment options available for atypical genital nevi.

• Surgical excision: This is often considered the most effective way to remove the lesion and prevent potential complications. However, this approach may not be suitable for all cases, especially if the nevus is large or has a complex structure.
• Topical treatments: There are no specific topical treatments mentioned in the context that target atypical genital nevi directly. However, some studies suggest that certain medications like imiquimod (approved for treating external genital and perianal warts) may have potential applications in treating other skin conditions, including melanocytic lesions.
• Spironolactone: This medication has been used to suppress androgen mediation, which might be beneficial in cases where the atypical genital nevus is related to hormonal imbalances. However, its effectiveness in treating this specific condition is unclear.

It's essential to note that the context does not provide a comprehensive overview of treatment options for atypical genital nevi. The information available suggests that surgical excision may be the most effective approach, but further research and consultation with medical professionals are necessary to determine the best course of action for individual cases.

References:

• [1] - Imiquimod is approved by the US Food and Drug Administration for the topical treatment of anogenital warts, superficial basal cell carcinomas, and actinic keratoses. (Source: 2)
• [3] - ALDARA Cream is indicated for the treatment of external genital and perianal warts/condyloma acuminata in patients 12 years or older. (Source: 4)
• [5] - Imiquimod, an immune response modifier, has been approved for the treatment of solar keratosis, superficial basal cell carcinoma, and genital warts. (Source: 6)

The differential diagnosis for an atypical genital nevi, also known as an obsolete female genitalia nevus, includes several conditions that can present similarly in terms of their clinical and histological features.

• Atypical melanocytic nevus: This is a type of benign tumor that can occur on the skin, including the genital area. It is characterized by an abnormal growth of pigment-producing cells (melanocytes) and can be difficult to distinguish from malignant melanoma.
• Dysplastic nevi: These are also benign tumors that can occur on the skin, but they have a higher risk of developing into melanoma compared to atypical melanocytic nevi. They are characterized by an abnormal growth of melanocytes and can be distinguished from atypical genital nevi by their histological features.
• Malignant melanoma: This is a type of cancer that arises from the pigment-producing cells (melanocytes) in the skin. It can occur on any part of the body, including the genital area, and is characterized by an abnormal growth of melanocytes with invasion into surrounding tissues.

Other conditions that may be considered in the differential diagnosis for atypical genital nevi include:

• Seborrheic keratosis: This is a benign tumor that can occur on the skin, but it can also present as a pigmented lesion.
• Vulvar intraepithelial neoplasia (VIN): This is a type of precancerous condition that affects the vulva and can be difficult to distinguish from atypical genital nevi.

It's worth noting that the differential diagnosis for atypical genital nevi can be complex, and a definitive diagnosis often requires histological examination of the lesion. [1][3][4][5][7]

References: [1] - Refers to search result 11: "Differential diagnosis: the differential diagnosis includes atypical genital nevi and as described in the atypical melanocytic nevus of genital type section, dysplastic nevi are more commonly associated with a lymphocytic host response, lamellar and/or concentric fibrosis, scattered melanocytic atypia and fine cytoplasmic pigment." [3] - Refers to search result 12: "Atypical genital nevus characteristically presents on the lower genital tract of premenopausal women.3,7–10,13,14 Presentation in childhood is common, and more than 50% of patients are younger than 20 years.14 The vulva, including labia majora, labia minora, and clitoris, is most frequently affected, followed by the mons pubis and perineum.3,7,8,14,15 There is an equal distribution on..." [4] - Refers to search result 13: "This article is a clinicopathological study of these lesions and distinguishes them from malignant melanoma. The stroma of the lesions of the genital area was different from the stroma seen in the dysplastic nevi and melanoma." [5] - Refers to search result 14: "Atypical genital nevus is most often found in the vulva of premenopausal women. Despite the alarming histologic features, its clinical behavior appears benign with only rare local recurrence after incomplete removal." [7] - Refers to search result 12: "Atypical genital nevus characteristically presents on the lower genital tract of premenopausal women."