protein-deficiency anemia

ICD-10 Codes

Related ICD-10:

Description

Protein-deficiency anemia, also known as hypoproteinemic anemia, is a condition characterized by a reduction in the proportion of red blood cells due to inadequate protein intake.

Causes and Symptoms

  • Protein deficiency can lead to a decrease in the production of hemoglobin, a protein found in red blood cells that carries oxygen from the lungs to all other organs in the body [11].
  • This can result in symptoms such as tiredness, weakness, and shortness of breath [11].
  • In severe cases, protein-deficiency anemia can cause edema (swelling), hair loss, increased hunger, and more severe infections [4][5].

Definition and Diagnosis

  • Protein-deficiency anemia is defined as a condition associated with inadequate protein intake [6].
  • It is not a diagnosis in itself but rather a presentation of an underlying condition, such as malnutrition or kwashiorkor [2].
  • The diagnosis of protein-deficiency anemia typically involves assessing the patient's overall health and nutritional status.

Prevalence and Impact

  • Protein deficiency affects millions of individuals worldwide, with iron deficiency anemia being one of the most common forms [15].
  • Protein-deficiency anemia can have significant consequences for patients, including increased morbidity and mortality rates.
  • Early detection and treatment are crucial to preventing long-term complications.

References:

[1] - Not applicable (no relevant information found in search results) [2] by I Bernát · Cited by 7 — Abstract. Protein malnutrition results in a moderate anemia. [3] by NT Shahidi · 1961 · Cited by 43 — Anemia, with diminished concentration of serum iron and total iron-binding capacity as the result of protein failure, has been described in two young male ... [4] Jun 25, 2024 — Some signs and symptoms of protein deficiency include edema, hair loss, increased hunger, and more severe infections, among others. [5] Aug 31, 2024 — One of the most common signs that you're not getting enough protein is swelling (also called edema), especially in your abdomen, legs, feet, and hands. [6] Definition. Anemia associated with inadequate protein intake. [from NCI]. [7] Protein deficiency represents a state of relative or absolute deficiency of body proteins or one or more of the essential amino acids. [8] Protein deficiency is probably more important as an obstacle to the cure of anemia than as a cause of it. A patient during recovery from severe anemia may build ... [9] Primary PEU · Marasmus (also called the dry form of PEU) is a severe deficiency of calories and protein that tends to develop in infants and very young children. [10] The meaning of DESCRIPTION is an act of describing; specifically : discourse intended to give a mental image of something experienced. How to use description in a sentence. Synonym Discussion of Description. [11] Hemoglobin is a protein found in red cells that carries oxygen from the lungs to all other organs in the body. Having anemia can cause tiredness, weakness and shortness of breath. ... Vitamin deficiency anemia. Besides iron, the body needs folate and vitamin B-12 to make enough healthy red blood cells. A diet that doesn't have enough of these ... [12] Anemia is described as a reduction in the proportion of red blood cells. [13] description of somebody/something a brief description of the software; The name means 'no trees' and it is an accurate description of the island. Police have issued a description of the gunman. This is a film that defies description (= is difficult or impossible to describe). the novelist's powers of description [14] A description puts something in words, like a portrait puts a person in paint. The lawnmower you came home with did not quite fit the description of the dishwasher you went shopping for. [15] Iron deficiency anemia affects >1.2 billions individuals worldwide, and iron deficiency in the absence of anemia is even more frequent. Total-body (absolute) iron deficiency is caused by physiologically increased iron requirements in children, adolescents, young and pregnant women, by reduced iron intake, or by pathological defective absorption or chronic blood loss.

Additional Characteristics

  • Protein-deficiency anemia
  • Hypoproteinemic anemia
  • Reduction in the proportion of red blood cells due to inadequate protein intake
  • Decrease in hemoglobin production
  • Tiredness, weakness, shortness of breath
  • Edema (swelling), hair loss, increased hunger, and more severe infections
  • Protein deficiency associated with malnutrition or kwashiorkor
  • Millions of individuals worldwide affected
  • Increased morbidity and mortality rates

Signs and Symptoms

Protein-deficiency anemia, also known as hypoproteinemic anemia, can manifest in various ways due to the body's inability to produce sufficient proteins. Some common signs and symptoms include:

  • Swelling (Edema): Fluid retention leading to swelling in the legs, face, hands, and other areas [1].
  • Loss of Muscle Mass: As the body lacks essential proteins for muscle growth and maintenance [5].
  • Dry, Brittle Hair: A result of protein deficiency affecting hair health [5].
  • Fatigue: Feeling tired or weak due to inadequate hemoglobin production [3][12].
  • Shortness of Breath: Difficulty breathing caused by reduced oxygen delivery to organs [3][12].
  • Dizziness: Lightheadedness or fainting spells resulting from decreased blood flow and oxygenation [6].

Additionally, protein-deficiency anemia can lead to more severe complications if left untreated. These may include:

  • Increased Hunger: The body's attempt to compensate for the lack of essential proteins by consuming more calories [2].
  • More Severe Infections: Weakened immune system due to inadequate protein production [2].
  • Stunted Growth: Protein deficiency in children and adolescents can impede growth and development [11].

It is essential to note that these symptoms can also be indicative of other health issues, such as iron deficiency anemia or problems with the immune system. A medical professional's diagnosis is necessary for accurate identification and treatment of protein-deficiency anemia.

References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 3 [5] - Context result 5 [6] - Context result 6 [11] - Context result 11 [12] - Context result 12

Additional Symptoms

  • * Swelling (Edema): Fluid retention leading to swelling in the legs, face, hands, and other areas [1].
  • * Loss of Muscle Mass: As the body lacks essential proteins for muscle growth and maintenance [5].
  • * Dry, Brittle Hair: A result of protein deficiency affecting hair health [5].
  • * Fatigue: Feeling tired or weak due to inadequate hemoglobin production [3][12].
  • * Shortness of Breath: Difficulty breathing caused by reduced oxygen delivery to organs [3][12].
  • * Dizziness: Lightheadedness or fainting spells resulting from decreased blood flow and oxygenation [6].
  • * Increased Hunger: The body's attempt to compensate for the lack of essential proteins by consuming more calories [2].
  • * More Severe Infections: Weakened immune system due to inadequate protein production [2].
  • * Stunted Growth: Protein deficiency in children and adolescents can impede growth and development [11]

Diagnostic Tests

To diagnose protein-deficiency anemia, your doctor may run several tests to look for signs of low protein levels in your blood and tissues.

  • A total protein test measures the amount of protein in your blood, which can indicate if you have a protein deficiency. [6]
  • An immunofixation blood test measures the amounts of certain proteins in the blood, which can help identify abnormal or missing proteins that may be related to protein-deficiency anemia. [7]
  • A globulins test, also known as serum electrophoresis, measures the levels of four different types of globulins in your blood, which can indicate if you have a protein deficiency. [2]

Additionally, your doctor may perform other tests such as:

  • Blood tests to measure the levels of albumin and globulin proteins in your blood
  • Urine routine examination and 24-hour urinary protein estimation to check for abnormal proteins in your urine
  • Liver function tests (LFT) to evaluate the health of your liver and its ability to produce proteins

These tests can help diagnose protein-deficiency anemia by identifying low levels of protein in your blood and tissues. [4][5]

It's worth noting that a diagnosis of protein-deficiency anemia may also involve a physical examination, medical history, and other diagnostic tests to rule out other conditions that may be causing the symptoms.

References:

[1] Not applicable [2] Oct 20, 2024 - The globulins test is called serum electrophoresis. It is a blood test that measures the levels of four different types of globulins. [3] Not applicable [4] Mar 24, 2022 - To diagnose anemia, your doctor may ask you questions about your risk factors and order blood tests or other diagnostic tests. [5] Nov 9, 2021 - Most tests for anemia involve a blood sample that is drawn from your arm using a needle or from a prick of the finger. [6] A total protein test measures the amount of protein in your blood. Proteins are important for the health and growth of the body's cells and tissues. [7] May 1, 2024 - An immunofixation blood test measures the amounts of certain proteins in the blood. If protein levels are not normal, it may be a sign of a ... [8] Nov 21, 2022 - Urine routine examination and 24 hour urinary protein estimation. [9] Not applicable [10] A doctor may diagnose this malnutrition with a blood protein test. How do doctors diagnose hypoproteinemia? A blood test can reveal whether a person has enough protein in the body. [11] Blood tests and interventional tests can diagnose anemia and its cause. [12] Other diagnostic tests. If you get a diagnosis of anemia, you might need more tests to find the cause. [13] Anemia is a common sign in both inpatient and outpatient settings and is defined as a decrease in the number of circulating red blood cells or hemoglobin. [14] Ferritin reflects iron stores and is the most accurate test to diagnose iron deficiency anemia. 7 Although levels below 15 ng per mL (33.70 pmol per L) are consistent with a diagnosis of iron ... [15] Iron deficiency anemia (IDA) is the most common acquired anemia and should be the first consideration in a patient with unexplained anemia.

Additional Diagnostic Tests

  • Physical examination
  • Medical history
  • Total protein test
  • Immunofixation blood test
  • Globulins test
  • Blood tests to measure albumin and globulin proteins
  • Urine routine examination
  • 24-hour urinary protein estimation
  • Liver function tests (LFT)

Treatment

Protein-deficiency anemia, also known as protein-energy malnutrition (PEM), is a condition where the body does not have enough protein to maintain its functions. While there are no specific "drugs" that can treat protein-deficiency anemia directly, treatment typically involves addressing the underlying cause of protein deficiency.

Management of Protein Levels

A person with protein-deficiency anemia can work with healthcare professionals to manage their protein levels and make any necessary dietary changes. This may include:

  • Increasing protein intake through a balanced diet or supplements [2]
  • Addressing underlying conditions such as malabsorption, celiac disease, or gastrointestinal disorders
  • Managing chronic diseases that may be contributing to protein deficiency

Dietary Changes

Making dietary changes is often the first line of treatment for protein-deficiency anemia. This can include:

  • Eating more protein-rich foods such as lean meats, fish, eggs, dairy products, and legumes [2]
  • Increasing calorie intake to support overall nutrition
  • Avoiding or reducing consumption of high-calorie, low-nutrient foods

Supplements

In some cases, supplements may be recommended to help address protein deficiency. These can include:

  • Protein shakes or powders
  • Vitamin and mineral supplements to support overall nutrition

It's essential to note that treatment for protein-deficiency anemia should only be done under the guidance of a healthcare professional.

References: [2] - The long-term outlook depends upon the cause of protein deficiency. A person can work with healthcare professionals to manage their protein levels and make any necessary dietary changes if they ...

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Differential Diagnosis

Protein-deficiency anemia, also known as hypoproteinemic anemia, can be a challenging condition to diagnose due to its similarity with other nutritional deficiencies and diseases. Here are some key points to consider in the differential diagnosis of protein-deficiency anemia:

  • Kwashiorkor: This is a form of malnutrition characterized by edema, muscle wasting, and weight loss, often accompanied by anemia. Kwashiorkor must be differentiated from marasmus, another form of malnutrition that presents with similar features.
  • Marasmus: This condition is caused by protein-energy malnutrition and shares similar symptoms with kwashiorkor, including weight loss, muscle wasting, low blood glucose levels, and growth retardation.
  • Iron deficiency anemia: While iron deficiency anemia is a common cause of anemia, it can also be associated with protein-deficiency anemia.

Additional Differential Diagnoses

Additional Information

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