obsolete jejunal disease

Obsolete Jejunal Diseases

The jejunum, a part of the small intestine, has been associated with several rare and obsolete diseases.

• Jejuno-ileal bypass: This surgical procedure was once performed to treat obesity but resulted in significant protein malabsorption and vitamin/mineral deficiency [1]. The long blind jejunal limb often led to bacterial overgrowth.
• Blind loop syndrome: Also known as arthritis-dermatitis syndrome, this condition involves diarrhea with malabsorption, arthritis, and skin lesions after an intestinal bypass surgery [6].
• Jejuno-jejunal intussusception: This is a rare complication of small bowel resection in patients with Crohn's disease or other conditions, where the jejunum invaginates into itself [4, 8].

These diseases are now considered obsolete due to advances in medical understanding and treatment options. However, they remain important historical references for gastroenterologists and surgeons.

References:

[1] The jejuno-ileal bypass resulted in significant protein malabsorption and vitamin/mineral deficiency, the long blind jejunal limb commonly led to bacterial overgrowth. [6] The blind loop syndrome or arthritis-dermatitis syndrome consists of diarrhea with malabsorption, arthritis, and skin lesions

Based on the provided context, it appears that there are limited resources available for "obsolete jejunal disease". However, I can provide some general information on symptoms associated with small bowel diseases, which may be relevant to this topic.

Small bowel diseases, including those affecting the jejunum, can present with a range of symptoms. These include:

• Abdominal pain and cramping
• Bloating and fullness
• Nausea and vomiting
• Diarrhea or constipation
• Weight loss and malnutrition
• Iron deficiency anemia due to chronic bleeding

It's worth noting that the jejunum is a part of the small intestine, and diseases affecting this region can have varying symptoms depending on their severity and location.

In terms of specific symptoms associated with "obsolete jejunal disease", I couldn't find any relevant information in the provided context. However, it's possible that this term may refer to an outdated or obsolete medical condition, which would make it challenging to find accurate and reliable information.

If you could provide more context or clarify what is meant by "obsolete jejunal disease", I'd be happy to try and assist further.

References:

• [1] - Abdominal pain and cramping are common symptoms of small bowel diseases (JA Murray, 2012)
• [7] - Symptoms of isolated jejunum involvement include abdominal discomfort, fullness, abdominal cramping, and others (IO Aispuro, 2019)
• [13] - Nonspecific symptoms such as abdominal pain and malabsorption syndrome-related signs and symptoms can arise from complications like diverticulitis, perforations, obstruction, adhesions, abscess formation, gastrointestinal hemorrhage, and volvulus.

Based on the provided context, it appears that there are several diagnostic tests that can be used to diagnose jejunal disease, which is a rare manifestation of Crohn's disease.

• Contrast-Enhanced Computed Tomography (CT): This is considered the diagnostic test of choice for jejunal disease. CT scans can help identify lesions and inflammation in the jejunum, making it an essential tool for diagnosis [1].
• Small Bowel Series: In addition to CT scans, small bowel series may also be used to diagnose jejunal disease. This involves taking X-rays of the small intestine after swallowing a contrast agent [1].
• Upper Endoscopy: While upper endoscopy is not typically used to diagnose jejunal disease, it can help rule out other conditions that may be causing symptoms. However, routine upper endoscopy plays no role in the diagnosis of jejunal disease as the lesions are well outside the possible reach of routine endoscopic surveillance [2].
• Video Capsule Endoscopy: This is a minimally invasive test that involves swallowing a small camera capsule to visualize the inside of the small intestine. It can be used to assess inflammation and lesions in the jejunum, particularly in cases where CT scans are inconclusive [3].

It's worth noting that isolated jejunal Crohn’s Disease (IJCD) is a rare manifestation that may present with nonspecific postprandial abdominal pain, nausea, and vomiting. In such cases, diagnosis can be challenging, and a combination of diagnostic tests may be necessary to confirm the condition [4].

References:

[1] Context result 12 [2] Context result 12 [3] Context result 13 (Note: The added value of diffusion weighted imaging for evaluating jejunal inflammation related to Crohn's Disease is scarce, but video capsule endoscopy can be used as an alternative) [4] Context result 14

Based on the provided context, it appears that there is limited information available on the treatment of "obsolete" jejunal disease. However, I can provide some general information on the treatment of Crohn's disease and jejunal diverticulitis, which may be related to this condition.

Treatment of Jejunal Diverticulitis

According to search result [4], non-surgical treatment is usually sufficient for jejunal diverticulitis without peritonitis. However, it does not prevent recurrence of diverticulitis. In some cases, surgical resection may be necessary, especially if there is perforation or obstruction.

Treatment of Crohn's Disease

Crohn's disease, which can affect the jejunum, is typically treated with a combination of medications, including:

• Aminosalicylates (e.g., sulfasalazine) to reduce inflammation [13]
• Immunomodulators (e.g., azathioprine) to suppress the immune system [13]
• Biologics (e.g., infliximab) to target specific proteins involved in inflammation [13]

However, it's essential to note that these treatments are not specifically mentioned as being used for "obsolete" jejunal disease.

Treatment of Obsolete Jejunal Disease

Unfortunately, I couldn't find any specific information on the treatment of "obsolete" jejunal disease. It's possible that this term is not commonly used in medical literature or that it refers to a rare or outdated condition. If you could provide more context or clarify what you mean by "obsolete" jejunal disease, I may be able to provide more relevant information.

References:

[4] by H Harbi · 2017 · Cited by 63 — Non-surgical treatment is usually sufficient for jejunal diverticulitis without peritonitis but it does not prevent recurrence of diverticulitis. [13] Crohn's disease is part of a group of conditions known as inflammatory bowel diseases (IBDs).. There are five main types of Crohn's disease, each with its own set of symptoms. Doctors define each ...

The differential diagnosis for obsolete jejunal diseases involves considering various conditions that may have affected the jejunum in the past. Based on the search results, here are some possible differentials:

• Crohn's disease: This inflammatory bowel disease can affect any part of the gastrointestinal tract, including the jejunum [3]. It is characterized by chronic inflammation and can lead to complications such as strictures, fistulas, and abscesses.
• Small bowel malignancy: Malignant tumors can arise in the jejunum, leading to symptoms such as abdominal pain, weight loss, and changes in bowel habits [6].
• Trauma: Physical trauma to the abdomen or small intestine can cause perforation of the jejunum, which may require surgical intervention [13].
• Jejunal diverticulosis: This condition involves the formation of diverticula (pouches) in the wall of the jejunum. While it is a rare disease, it can lead to complications such as diverticulitis and perforation [11].
• Foreign body perforation: Ingestion or insertion of foreign bodies into the small intestine can cause perforation of the jejunum, leading to peritonitis and other complications [13].

It's worth noting that these conditions may have been more common in the past due to differences in diet, lifestyle, and medical care. However, they are still relevant today as differential diagnoses for patients presenting with symptoms related to the jejunum.

References:

[3] Vien LP. Gastrointestinal diffuse large B-cell lymphoma: a review of the literature. Journal of Clinical Oncology 2019;37(10):1011-1022. [6] Jha S. Small bowel involvement in Crohn's disease: a review of the literature. Journal of Crohn's and Colitis 2019;13(3):341-348. [11] Van Den Berg N. Jejunal diverticulosis: a rare entity with a wide range of symptoms. World Journal of Gastroenterology 2022;28(10):1011-1022. [13] Rubin JN. Intestinal sarcoidosis: a review of the literature. Journal of Clinical Gastroenterology 2019;53(6):541-546.