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temporal arteritis
Description
Temporal arteritis, also known as giant cell arteritis (GCA), is an inflammatory disease that affects the blood vessels in the head and neck region. The condition is characterized by inflammation and damage to the arteries, particularly those at the side of the head (the temples) [3].
The symptoms of temporal arteritis can vary from person to person but often include:
- Headaches
- Difficulty chewing or swallowing
- Sudden irreversible vision loss in one eye (this is a medical emergency)
- Jaw claudication (pain and weakness in the jaw when eating or talking)
Temporal arteritis is an autoimmune condition, which means that the body's immune system mistakenly attacks its own tissues [7]. The exact cause of the disease is unknown, but it is believed to be related to aging and genetic predisposition.
It's essential to seek medical attention immediately if you experience sudden vision loss in one eye or any other symptoms associated with temporal arteritis. Early diagnosis and treatment can help prevent long-term damage and improve outcomes [4].
References: [1] Not available [2] Not available [3] Context 3 [4] Context 4 [7] Context 7
Additional Characteristics
- Headaches
- Genetic predisposition
- Difficulty chewing or swallowing
- Aging
- Temporal arteritis
- Sudden irreversible vision loss in one eye
- Jaw claudication (pain and weakness in the jaw when eating or talking)
- Autoimmune condition
Signs and Symptoms
Temporal arteritis, also known as giant cell arteritis (GCA), is a condition that affects the blood vessels in the head, neck, and scalp. The symptoms can vary from person to person, but here are some common signs and symptoms:
- Headache: A severe, persistent, and possibly throbbing headache is one of the main symptoms of temporal arteritis. It usually occurs on one side or at the front of the head [6].
- Jaw pain: Jaw pain that occurs when chewing (called jaw claudication) is a common symptom of GCA [2][3].
- Scalp tenderness: Tenderness at your scalp or temples can be another sign of temporal arteritis [1][2].
- Fatigue: Feeling tired and exhausted is also a symptom of GCA [4].
- Vision problems: Episodes of blurred or darkened vision can occur, usually affecting one eye. In some cases, visual loss can be quite sudden and severe [8].
- Arm pain: Pain in the arm after using it can also be a sign of temporal arteritis [3].
- Muscle aches: Muscle aches and pain can occur in various parts of the body.
- Pain and stiffness in the neck, upper arms, and shoulders: These areas can experience pain and stiffness due to inflammation.
It's essential to seek medical attention if you're experiencing any of these symptoms, as prompt treatment can help prevent further complications.
Diagnostic Tests
Temporal arteritis, also known as giant cell arteritis (GCA), can be diagnosed through several tests.
Biopsy: The best way to confirm a diagnosis of GCA is by taking a small sample (biopsy) of the temporal artery [1]. This artery is often affected in GCA. A biopsy can be carried out as an outpatient procedure under local anesthesia [3].
Imaging Tests: Imaging tests such as ultrasound, positron emission tomography (PET), and magnetic resonance imaging (MRI) may also be ordered to help diagnose GCA [6]. These tests can show signs of inflammation in the arteries.
Laboratory Testing: Laboratory testing may also be used to support a diagnosis of GCA. However, these tests are not specific for GCA and should be interpreted in conjunction with clinical findings [4].
It's worth noting that while biopsy is considered the diagnostic gold standard for GCA, it has many limitations, including low sensitivity and specificity [8]. Therefore, a diagnosis of GCA may also be made based on clinical suspicion and imaging tests.
References: [1] - A small sample (biopsy) of the temporal artery is taken to confirm a diagnosis of giant cell arteritis. [3] - A biopsy can be carried out as an outpatient procedure under local anesthesia. [4] - Laboratory testing may also be used to support a diagnosis of GCA. [6] - Imaging tests such as ultrasound, PET, and MRI may be ordered to help diagnose GCA. [8] - Biopsy has many limitations, including low sensitivity and specificity.
Additional Diagnostic Tests
- Biopsy
- Laboratory Testing
- Imaging Tests (ultrasound, positron emission tomography (PET), magnetic resonance imaging (MRI))
Treatment
Treatment Overview
The main treatment for temporal arteritis, also known as giant cell arteritis (GCA), involves high doses of corticosteroid medication to reduce inflammation in the arteries.
- Corticosteroids: The primary medication used to treat GCA is a corticosteroid, such as prednisone. This medication helps to reduce inflammation and prevent further damage to the blood vessels.
- Dosage and Duration: Treatment typically starts with high doses of corticosteroids (40-60 mg/day) for an extended period, often up to 2 years or longer.
Additional Medications
While corticosteroids are the primary treatment, other medications may be prescribed to manage symptoms and prevent complications:
- Calcium and Vitamin D: Patients with GCA may need to take extra calcium and vitamin D supplements to maintain bone health.
- Bisphosphonates: These medications can help prevent osteoporosis in patients taking long-term corticosteroids.
Importance of Early Treatment
Early treatment is crucial to prevent vision loss, which is a common complication of GCA. Even before confirming the diagnosis with a biopsy, doctors may start medication to prevent further damage.
References
- [1] The main treatment for giant cell arteritis consists of high doses of a corticosteroid drug such as prednisone.
- [3] Giant cell arteritis frequently causes headaches, scalp tenderness, jaw pain and vision problems.
- [5] Temporal arteritis is treated with steroid medicine, usually prednisolone.
- [9] Temporal arteritis treatment should begin immediately to prevent vision loss. The main medication choice for the condition is glucocorticoids, like oral prednisone.
- [11] The main treatment for temporal arteritis is corticosteroids.
- [13] The main treatment is high doses of steroids, such as prednisone, to reduce inflammation in the arteries.
Recommended Medications
- Corticosteroids
- Bisphosphonates
- Calcium and Vitamin D supplements
- prednisone
- Prednisone
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Temporal arteritis, also known as giant cell arteritis, can be challenging to diagnose due to its non-specific symptoms and lack of distinctive laboratory findings. Therefore, a differential diagnosis is essential to rule out other conditions that may present similarly.
Other Conditions to Consider:
- Polymyalgia Rheumatica (PMR): A condition characterized by muscle pain and stiffness, often accompanied by fever and fatigue. PMR can be difficult to distinguish from temporal arteritis, especially in the early stages.
- Tension Headaches: Frequent or severe headaches can be a symptom of various conditions, including tension headaches, which may mimic the headache symptoms associated with temporal arteritis.
- Migraines: Migraine headaches can also present similarly to those experienced by individuals with temporal arteritis.
- Sinusitis: Inflammation of the sinuses can cause facial pain and tenderness, which may be mistaken for temporal arteritis.
- Temporomandibular Joint (TMJ) Disorder: TMJ disorders can cause jaw pain and clicking sounds, which may be confused with the jaw pain associated with temporal arteritis.
Key Diagnostic Features:
- Temporal Artery Biopsy: The gold standard for diagnosing temporal arteritis is a biopsy of the temporal artery. This procedure involves taking a small sample of tissue from the affected area.
- Elevated Inflammatory Markers: Blood tests may show elevated levels of inflammatory markers, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), which can support the diagnosis of temporal arteritis.
References:
- [4] The gold standard for diagnosis is tissue confirmation from a temporal artery biopsy.
- [6] Temporal artery biopsy procedure is essential for accurate diagnosis.
- [7] Treatment of patients with TA is critical to avoid vision loss, and therapy should be initiated based on clinical suspicion, not biopsy results.
Note: The above information is based on the search results provided in the context.
Additional Differential Diagnoses
Additional Information
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- A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head.
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.