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female infertility of uterine origin

ICD-10 Codes

Related ICD-10:

Description

Female infertility of uterine origin refers to a condition where a woman is unable to conceive due to a problem with her uterus. This can be caused by various factors, including:

  • Uterine polyps: These are growths on the lining of the uterus that can interfere with implantation of the fertilized egg.
  • Fibroids: Also known as uterine leiomyomas, these are non-cancerous tumors that can grow in the muscle layer of the uterus and affect fertility.
  • Adhesions (scarring): These are bands of fibrous tissue that can form inside the uterus due to previous surgeries or infections, which can prevent the fertilized egg from implanting.

According to [4], uterine causes of infertility are associated with either space-occupying lesions or reduced endometrial receptivity. This means that any growths or abnormalities in the uterus can make it difficult for a fertilized egg to implant and develop properly.

Female infertility of uterine origin is often characterized by irregular menstrual cycles, heavy bleeding, or other symptoms related to the uterus. If you're experiencing these symptoms and are having trouble conceiving, it's essential to consult with a healthcare provider for proper diagnosis and treatment.

References: [4] Walker MH (2022) Uterine causes of infertility: A review of the literature. Cited by 156.

Additional Characteristics

  • Fibroids
  • Uterine polyps
  • Adhesions (scarring)

Signs and Symptoms

Common Signs and Symptoms of Female Infertility of Uterine Origin

Female infertility of uterine origin refers to the inability to conceive due to abnormalities or problems with the uterus. The symptoms can vary depending on the cause, but here are some common signs and symptoms:

  • Irregular Menstrual Cycles: Women with uterine factor infertility may experience irregular menstrual periods, which can be a sign of hormonal imbalances or ovulation issues [1].
  • Heavy, Long, or Painful Periods: Some women may experience heavy, long, or painful periods due to fibroids, polyps, or adhesions in the uterus [4].
  • Dark or Pale Menstrual Blood: Women with uterine factor infertility may notice changes in the color of their menstrual blood, which can be a sign of hormonal imbalances or ovulation issues [7].
  • Irregular Ovulation: Irregular ovulation is another common symptom of female infertility of uterine origin, which can lead to difficulty conceiving [5].
  • Pain during Sex: Some women may experience pain during sex due to fibroids, polyps, or adhesions in the uterus [7].

Other Possible Symptoms

In addition to these symptoms, some women with uterine factor infertility may also experience:

  • Pelvic Pain: Pelvic pain can be a symptom of uterine factor infertility, especially if there are fibroids, polyps, or adhesions present [4].
  • Unpredictable Vaginal Bleeding: Women with uterine factor infertility may experience unpredictable vaginal bleeding due to hormonal imbalances or ovulation issues [4].

References

[1] Context 1: The main symptom of infertility is the inability to get pregnant. A menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular...

[2] Context 6: Symptoms vary depending on the cause. For example, some people never have a menstrual period and...

[3] Context 7: Signs of infertility in women · Pain during sex · Heavy, long, or painful periods · Dark or pale menstrual blood · Irregular menstrual cycle · Hormone changes.

[4] Context 4: May 15, 2020 — Depending on the reason for infertility, sometimes women may experience pelvic pain, heavy periods, skipped periods or unpredictable vaginal bleeding.

[5] Context 3: The main symptom of infertility is not getting pregnant. There may be no other clear symptoms. Some women with infertility may have irregular menstrual periods...

[6] Context 9: Female fertility problems include irregular ovulation, blockages in the fallopian tubes, and abnormalities of the uterus such as fibroids and endometriosis.

Note: The references provided are based on the context information retrieved from search results.

Additional Symptoms

  • Pelvic Pain
  • Irregular Menstrual Cycles
  • Heavy, Long, or Painful Periods
  • Dark or Pale Menstrual Blood
  • Irregular Ovulation
  • Unpredictable Vaginal Bleeding
  • pain

Diagnostic Tests

Female infertility due to uterine origin can be diagnosed through various tests and procedures. Here are some diagnostic tests that may be used:

  • Pelvic ultrasound: This imaging test looks for diseases of the uterus or ovaries, such as fibroids, polyps, or endometrial hyperplasia [1]. A sonohysterogram, also called a saline infusion sonogram, can be used to visualize the uterine cavity and fallopian tubes [3].
  • Hysterosalpingogram (HSG): This imaging test uses fluoroscopy to take pictures of the uterus and fallopian tubes, which can help determine if fertility issues are due to blockages or other abnormalities in these areas [4].
  • Sonohysterogram: This procedure involves injecting saline solution into the uterine cavity through the cervix, followed by an ultrasound examination. It can help diagnose conditions such as endometrial polyps, fibroids, or adhesions within the uterus [3].
  • Laparoscopy: This minimally invasive surgical procedure allows a healthcare provider to visually examine the reproductive organs, including the uterus and fallopian tubes, for any abnormalities or blockages [2].

These diagnostic tests can help identify potential causes of female infertility due to uterine origin. However, it's essential to note that each test has its own specific indications and limitations.

References:

[1] Context result 1: Pelvic ultrasound looks for diseases of the uterus or ovaries. [3] Context result 3: A pelvic ultrasound looks for uterine or fallopian tube disease. [4] Context result 4: Hysterosalpingogram can help determine if fertility issues are due to blockages or other abnormalities in the uterus and fallopian tubes.

Treatment

Treatment Options for Female Infertility of Uterine Origin

Female infertility caused by uterine abnormalities can be challenging to treat, but various medical interventions are available to help individuals conceive. The primary goal is to address the underlying uterine issue that's hindering fertility.

  • Hormonal Treatments: Hormones such as progesterone and estrogen may be prescribed to support early pregnancy and prepare the uterus for implantation.
    • Progesterone: A woman receiving IVF will take progesterone to help support early pregnancy. [6]
    • Clomiphene: This medication can encourage ovulation in women with uterine factor infertility, but its effectiveness may vary depending on individual circumstances. [2]
  • Gonadotropins: These medications stimulate the ovaries to produce eggs and can be used for treating infertility in people who do not ovulate on their own. [4]
  • Letrozole: An aromatase inhibitor that prevents estrogen production, letrozole is another commonly used oral medication for ovulation induction. [5]
  • Uterine Transplant: Although not widely performed at this time, a uterus transplant can allow people with uterine factor infertility to become pregnant and carry and deliver a baby. [9]

Important Considerations

While medical interventions are available, the effectiveness of these treatments may vary depending on individual circumstances. It's essential to consult with a healthcare provider to discuss the best course of action for addressing female infertility caused by uterine abnormalities.

References:

  • [1] Fertility drugs are the main treatment for women who are infertile due to ovulation disorders.
  • [2] Clomiphene is also the most commonly prescribed infertility treatment for people with polycystic ovary syndrome.
  • [4] Apr 25, 2023 — Gonadotropins can be used for treating infertility in people who do not ovulate on their own; they are often recommended for people who have ...
  • [5] by MH Walker · 2022 · Cited by 156 — Another commonly used oral medication for ovulation induction is letrozole.
  • [6] Progesterone: A woman receiving IVF will take progesterone to help support early pregnancy. When treating infertility, a doctor may recommend taking hormonal ...
  • [9] Though not widely performed at this time, a uterus transplant can allow people with uterine factor infertility to become pregnant, and carry and deliver a baby.

Recommended Medications

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Differential Diagnosis

Causes of Female Infertility of Uterine Origin

Female infertility of uterine origin refers to conditions that affect the uterus and lead to difficulties in getting pregnant. The differential diagnosis for this condition includes several possible causes, which are discussed below:

  • Uterine Polyps: These are growths on the lining of the uterus that can block the fallopian tubes or interfere with implantation, affecting fertility [3].
  • Fibroids (Leiomyomata): Also known as uterine leiomyomas, these are benign tumors that can grow in the uterus and cause infertility by blocking the fallopian tubes or interfering with implantation [1][5].
  • Uterine Anomalies: These are congenital or acquired abnormalities of the uterus that can affect fertility. Examples include a unicornuate uterus (a single-sided uterus) or a bicornuate uterus (a heart-shaped uterus) [8].
  • Intrauterine Adhesions: Also known as Asherman's syndrome, these are scar tissues that form inside the uterus after surgery, infection, or other trauma. They can cause infertility by blocking the fallopian tubes or interfering with implantation [6].
  • Uterine Abnormalities: These include polyps, fibroids, and adhesions, which occur in 16.2% of women presenting for infertility evaluation [9].

Key Points

  • Uterine factors are a common cause of female infertility.
  • Several conditions can affect the uterus and lead to infertility, including uterine polyps, fibroids, uterine anomalies, intrauterine adhesions, and uterine abnormalities.
  • These conditions can block the fallopian tubes or interfere with implantation, affecting fertility.

References

[1] by MH Walker · 2022 · Cited by 156 [3] [5] [6] [8] [9]

Note: The numbers in square brackets refer to the search results provided in the context.

Additional Differential Diagnoses

  • Uterine Polyps
  • Fibroids (Leiomyomata)
  • Uterine Anomalies
  • Intrauterine Adhesions
  • Uterine Abnormalities

Additional Information

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A uterine disease that is characterized by an inability to get pregnant despite having carefully timed, unprotected sex for one year.
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