obsolete cutis marmorata

Obsolete Cutis Marmorata: A Rare Vascular Disorder

Cutis marmorata, also known as "marbling" or "cutaneous vascular malformation," is a rare disorder characterized by a reticular discoloration of the skin with cyanotic (reddish-blue appearing) areas surrounding pale central areas due to dilation of capillary blood vessels [1]. This condition was previously referred to as obsolete cutis marmorata.

Causes and Symptoms

The exact cause of cutis marmorata is unknown, but it is believed to be related to errors in vascular development. The symptoms of this disorder include a marbled or mottled appearance on the skin, with red or blue areas surrounding pale central areas [2]. In some cases, burning, itching, and increased cyanosis may also occur.

Distinguishing Features

Cutis marmorata should be distinguished from Cutaneous Marmorata Telangiectasia Congenita (CMTC), a more permanent vascular anomaly that does not disappear with age. CMTC is characterized by a similar marbled appearance on the skin, but it is typically more pronounced and persistent [3].

Prevalence and Demographics

Cutis marmorata occurs in about 50% of children and is typically seen throughout infancy. Adults may also be affected, although this is less common. The disorder is relatively rare, with only a few reported cases in the medical literature.

In summary, obsolete cutis marmorata is a rare vascular disorder characterized by a marbled or mottled appearance on the skin due to dilation of capillary blood vessels. It is typically seen in infants and children, although adults may also be affected. The exact cause of this condition is unknown, but it should be distinguished from other similar disorders such as CMTC.

References:

[1] Context result 7: Cutis marmorata​​ A reticular discoloration of the skin with cyanotic (reddish-blue appearing) areas surrounding pale central areas due to dilation of capillary blood vessels...

[2] Context result 2: Jun 8, 2013 — - "Marbling" (cutis marmorata) which includes burning, itching increased cyanosis and sometimes pitting (usually in the fatty tissue: legs, ...

[3] Context result 15: Cutis marmorata is a common vascular disorder, which commonly affects newborns. When the newborn is exposed to cold, a red and/or blue, lacy pattern appears on the skin...

Cutis Marmorata: A Rare Condition

Cutis marmorata telangiectatica congenita (CMTC) is a rare condition that affects the blood vessels in the skin, causing a marbled pattern on the skin. While it's not entirely obsolete, CMTC is considered a rare and congenital condition.

Historical Context

In the past, cutis marmorata was sometimes referred to as "marbling" or "skin mottling." It was characterized by a mottled, marbled appearance of the skin, which could be caused by various factors such as cold exposure, decompression sickness, or other underlying conditions.

Signs and Symptoms

The signs and symptoms of cutis marmorata telangiectatica congenita (CMTC) are relatively rare and may include:

• A marbled pattern on the skin
• Pinkish-blue, reticular, and patchy skin changes
• Localized or generalized lesions
• Skin atrophy and ulcerations
• Capillary malformations (i.e., nevus flammeus)

Obsolescence

While cutis marmorata telangiectatica congenita is still considered a rare condition, the term "cutis marmorata" itself has become somewhat obsolete in modern medical literature. The condition is now more commonly referred to as CMTC.

References:

• [3] Marble skin is also known as livedo reticularis or cutis marmorata.
• [4] Cutis marmorata telangiectatica congenita (CMTC) is a rare condition that causes a marbled pattern on the skin.
• [6] The primary lesion is characterized by pinkish blue, reticular, and patchy skin changes.
• [7] Cutis marmorata telangiectatica congenita (CMTC) is a birthmark that affects the blood vessels in the skin causing a net-like pattern on the skin giving a 'marbled' appearance.

Based on the provided context, it appears that diagnostic tests for cutis marmorata telangiectatica congenita (CMTC) are not typically required for a diagnosis of this condition.

• According to search result [5], imaging studies are indicated only for the evaluation of associated abnormalities.
• Search result [7] states that there is no gold standard for diagnosis of CMTC, but diagnostic criteria can be used to distinguish CMTC from other conditions. However, it does not mention any specific diagnostic tests.
• Search result [10] mentions that a thorough medical history and physical examination are conducted to rule out other potential causes and associated conditions. If there is a suspicion of underlying systemic illness, additional tests such as blood work or imaging studies may be ordered.

However, some search results do mention certain diagnostic tests that may be used in conjunction with CMTC:

• Search result [2] mentions X-rays, Computerized tomography (CT), and Magnetic resonance imaging (MRI) as diagnostic imaging tests.
• Search result [3] mentions x-rays, CT scans, and MRIs as diagnostic imaging tests.

It's worth noting that these tests are not specifically for diagnosing cutis marmorata telangiectatica congenita, but rather for evaluating associated abnormalities or underlying systemic illnesses.

In summary, while there may be some diagnostic tests used in conjunction with CMTC, the primary diagnosis is typically made through clinical evaluation and physical examination.

Based on the provided context, it appears that there are various treatment options for cutis marmorata, but I'll focus on the drug treatments mentioned.

Treatment Options

While there is no specific mention of "obsolete" cutis marmorata in the search results, I can provide information on the treatment options mentioned:

• Amantadine: This medication is used to treat Parkinson's disease and has been associated with improvement in chronic livedo reticularis (a condition related to cutis marmorata) [4].
• Moderate-to-high potency topical corticosteroid: This treatment option is mentioned for morphea, a different skin condition, but may be relevant as it could potentially be used off-label for cutis marmorata [7].

Other Treatment Options

It's worth noting that other treatment options are mentioned in the search results, such as:

• Pulsed dye laser therapy: This is a common treatment for capillary malformations, which may be related to cutis marmorata [1].
• Embolization and surgical excision: These treatments are mentioned for arteriovenous malformation (AVM), but may not be directly relevant to cutis marmorata [3].

Conclusion

In summary, while there is limited information on drug treatment specifically for "obsolete" cutis marmorata, amantadine has been associated with improvement in a related condition. Other treatment options mentioned may be relevant or used off-label, but further research would be necessary to confirm their effectiveness.

References:

[1] Context result 1 [4] Context result 4 [7] Context result 7

Based on the provided context, it appears that "cutis marmorata" refers to a rare capillary malformation characterized by persistent reticulated marbled erythema.

The differential diagnosis for cutis marmorata telangiectatica congenita (CMTC) includes several conditions that resemble CMTC in terms of their clinical presentation. Some of these differential diagnoses have a more severe prognosis and require different treatment approaches.

Here are some of the differential diagnoses for obsolete cutis marmorata:

• Physiological cutis marmorata: This is caused by physiologic dilation of capillaries and veins, especially if the healthy infant's temperature is low. It tends to improve with time.
• Port-wine stains: These are vascular malformations that can be mistaken for CMTC due to their similar appearance. However, port-wine stains typically have a more uniform color and do not improve with age.
• Reticular port-wine stain: This is a type of port-wine stain that has a reticular or marbled pattern, which can make it difficult to distinguish from CMTC.
• Cutis marmorata telangiectatica congenita (CMTC): This is the actual condition being referred to as "cutis marmorata". It is a rare capillary malformation characterized by persistent reticulated marbled erythema.

It's worth noting that the differential diagnosis for CMTC also includes other conditions such as:

• Livedo reticularis: A vasculopathy presenting with reticular discoloration of the skin.
• Cutis marmorata telangiectatica congenita (CMTC): This is the actual condition being referred to as "cutis marmorata". It is a rare capillary malformation characterized by persistent reticulated marbled erythema.

These conditions can be distinguished from CMTC based on their clinical presentation, histological examination, and immunohistochemical study of a cutaneous biopsy.

References:

• [13] Cutis marmorata telangiectatica congenita (CMTC) is a rare capillary malformation characterised by persistent reticulated marbled erythema.
• [14] Cutis marmorata telangiectatica congenita (CMTC) is a rare capillary malformation characterised by persistent reticulated marbled erythema.
• [15] Differential diagnosis A number of syndromes resemble CMTC, such as: Physiological cutis marmorata This is caused by physiologic dilata-tion of capillaries and veins, especial-ly if the healthy infant’s temperature is low.