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obsolete glaucoma associated with vascular disorder
Description
Glaucoma Associated with Vascular Disorder
Glaucoma associated with vascular disorder refers to a type of secondary angle-closure glaucoma that is caused by abnormal new blood vessel formation, leading to the closure of the angle in the eye. This condition is often a result of underlying ocular and/or systemic diseases that affect the blood vessels in the eye.
- Neovascularization: The formation of new, fragile blood vessels can lead to increased intraocular pressure (IOP) and damage to the optic nerve.
- Vascular disorder: Abnormalities in the blood vessels, such as atherosclerosis or reduced ocular blood flow, can contribute to glaucoma development.
According to [1], neovascularization of the angle is a finding associated with this type of glaucoma. The disease is often a manifestation of advanced systemic vascular disease, and its clinical outcomes have been reported in various studies (e.g., [3]).
Key Points:
- Glaucoma associated with vascular disorder is a secondary angle-closure glaucoma.
- Abnormal new blood vessel formation leads to increased IOP and optic nerve damage.
- Vascular disorders, such as atherosclerosis or reduced ocular blood flow, contribute to disease development.
- Neovascularization of the angle is a finding associated with this type of glaucoma.
References:
[1] Glaucoma associated with vascular disorder (disorder) 路 Secondary angle-closure glaucoma (disorder) 路 Neovascularization of angle (finding). Descendant Tree ...
[3] Krupin et al. Clinical outcomes of valve implant surgery in 79 eyes affected by NVG. In his case ...
Additional Characteristics
- Atherosclerosis
- Increased intraocular pressure (IOP)
- Glaucoma associated with vascular disorder
- Neovascularization
- Vascular disorder
- Optic nerve damage
- Reduced ocular blood flow
- Neovascularization of the angle
Signs and Symptoms
Warning Signs of Obsolete Glaucoma Associated with Vascular Disorder
Glaucoma, a leading cause of irreversible blindness worldwide, can be associated with various vascular disorders. The signs and symptoms of obsolete glaucoma linked to vascular disease are crucial for early detection and treatment.
- Redness and Pain: Redness and pain in the eye are common warning signs of neovascular glaucoma, which is a type of glaucoma associated with diabetes and other vascular diseases [10].
- Vision Loss: Vision loss, particularly in low light environments, can be an early symptom of glaucoma linked to vascular disease [1].
- Optic Disc Hemorrhages: Optic disc hemorrhages, a clinical appearance of optic disc cupping, and areas of retinal ischemia are diagnostic signs of glaucoma associated with vascular disease [7].
- Fast Visual Field Progression: Fast visual field progression is associated with depressive symptoms in patients with glaucoma linked to vascular disease [6].
Other Vascular-Related Glaucomas
- Central Retinal Vein Occlusion: Central retinal vein occlusion, a condition where the central retinal vein is blocked, can lead to neovascular glaucoma and vision loss [9].
- Carotid Artery Obstructive Disease: Carotid artery obstructive disease, which affects blood flow to the eye, can increase intraocular pressure (IOP) and contribute to glaucoma development [3].
Early Detection and Treatment
Early detection and treatment of glaucoma associated with vascular disease are crucial for preventing vision loss. Annual eye exams and glaucoma screenings are essential for individuals with diabetes or at risk of vascular disease [10].
Diagnostic Tests
Diagnostic Tests for Obsolete Glaucoma Associated with Vascular Disorder
Obtaining an accurate diagnosis of glaucoma, particularly in cases associated with vascular disorders, is crucial for effective treatment and management. Various diagnostic tests can help identify the presence of glaucoma and its relationship with vascular abnormalities.
- Tonometry: This test measures the pressure inside the eye (intraocular pressure) to determine if it's within a normal range or elevated, which could indicate glaucoma [3].
- Ophthalmoscopy: A comprehensive eye examination using an ophthalmoscope can help assess the structure of the optic nerve and detect any signs of damage [2].
- GDx Nerve Fiber Analysis (GDx): This test uses laser technology to measure the thickness of the retinal nerve fiber layer, which can indicate glaucoma-related damage [7].
- Perimetry Test: A visual field examination can help identify areas where vision is affected due to glaucoma [9].
- Gonioscopy: This test allows ophthalmologists to examine the angle between the iris and cornea, which can be affected in cases of glaucoma [5].
These diagnostic tests provide valuable information about the presence and severity of glaucoma, as well as its relationship with vascular disorders. A comprehensive eye examination by an experienced ophthalmologist is essential for obtaining an accurate diagnosis and developing an effective treatment plan.
References:
[1] Context result 6 [2] Context result 7 [3] Context result 3 [4] Context result 9 [5] Context result 13
Additional Diagnostic Tests
- Tonometry
- Gonioscopy
- Ophthalmoscopy
- GDx Nerve Fiber Analysis (GDx)
- Perimetry Test
Treatment
Treatment Options for Glaucoma Associated with Vascular Disorder
Glaucoma associated with a vascular disorder, also known as neovascular glaucoma (NVG), is a complex condition that requires a comprehensive treatment approach. While the exact cause of NVG is not fully understood, it is believed to be related to abnormal blood vessel growth in the eye.
Treatment Goals
The primary goal of treating NVG is to stabilize intraocular pressure (IOP) and prevent further vision loss. Treatment options for NVG typically involve a combination of medications and surgical interventions.
- Anti-VEGF injections: These are used to treat the underlying retinal problem that contributes to NVG. Anti-VEGF drugs, such as bevacizumab or ranibizumab, can help reduce vascular endothelial growth factor (VEGF) levels in the eye, thereby slowing down abnormal blood vessel growth.
- Retinal laser treatment: This is used to destroy abnormal blood vessels and promote healing in the retina. Laser treatment can also help reduce IOP by improving drainage of fluid from the eye.
Medications
In addition to anti-VEGF injections and retinal laser treatment, medications may be prescribed to manage NVG. These include:
- Carbonic anhydrase inhibitors: These work by decreasing the rate of fluid production in the eye, thereby reducing IOP.
- Alpha-agonists: These can help reduce IOP by constricting blood vessels and improving drainage of fluid from the eye.
Surgical Interventions
In some cases, surgical interventions may be necessary to manage NVG. These include:
- Filtration surgery: This involves creating a new drainage channel in the eye to improve fluid outflow and reduce IOP.
- PRP (Panretinal Photocoagulation): This is a laser treatment that can help stabilize IOP by promoting healing in the retina.
References
- [3] Second-line treatments for IOP reduction include alpha-agonists and topical carbonic anhydrase inhibitors. These classes of drugs are typically used when first-line treatments are ineffective.
- [8] The treatment of neovascular glaucoma is two-fold, involving anti-VEGF drug injections and retinal laser treatment to address the underlying retinal problem.
- [9] PRP may stabilize IOP in the open-angle glaucoma stage of NVG and improve the outcome of filtration surgery if performed preoperatively.
Recommended Medications
- Carbonic anhydrase inhibitors
- Anti-VEGF injections
- Retinal laser treatment
- Alpha-agonists
馃拪 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
Differential Diagnosis of Obsolete Glaucoma Associated with Vascular Disorder
Obsolete glaucoma, also known as neovascular glaucoma (NVG), is a severe form of glaucoma that occurs due to vascular ischemia in various diseases. When diagnosing obsolete glaucoma associated with vascular disorders, it's essential to consider the following differential diagnoses:
- Inflammatory open angle glaucoma: This condition can mimic NVG and should be ruled out through thorough examination and investigation.
- Retrobulbar hemorrhage or inflammation: Bleeding or inflammation behind the eye can cause increased intraocular pressure, leading to symptoms similar to NVG.
- Traumatic (hemolytic) glaucoma: Trauma to the eye can lead to hemolysis, resulting in increased intraocular pressure and symptoms similar to NVG.
- Glaucomatocyclitic crisis: This is a rare condition characterized by recurrent episodes of uveitis and secondary glaucoma, which can be mistaken for NVG.
Other Considerations
In addition to these differential diagnoses, it's also essential to consider the following factors when diagnosing obsolete glaucoma associated with vascular disorders:
- Ischemic retinovascular diseases: These conditions can give rise to glaucoma through different mechanisms leading to angle closure from neovascularization of the iris.
- Normal tension glaucoma: This condition is closely associated with general issues of blood circulation and organ perfusion, such as arterial hypotension and metabolic disorders.
References
- The three most common conditions responsible for NVG are diabetic retinopathy, central retinal vein occlusion, and carotid artery obstructive disease [1].
- Differential diagnosis of hypotony maculopathy and chorioretinal fold includes: Tumors (choroidal melanomas and metastasis) [4].
- Glaucoma is likely a primary vascular disease due to reduced ocular blood flow [5].
- DIFFERENTIAL DIAGNOSIS 路 Inflammatory open angle glaucoma 路 Retrobulbar hemorrhage or inflammation 路 Traumatic (hemolytic glaucoma) 路 Glaucomatocyclitic crisis [6].
- Ischemic retinovascular diseases give rise to glaucoma through different mechanisms leading to angle closure from neovascularization of the iris [8].
Note: The numbers in square brackets refer to the corresponding search results provided in the context.
Additional Differential Diagnoses
- Retrobulbar hemorrhage or inflammation
- Traumatic (hemolytic) glaucoma
- Inflammatory open angle glaucoma
- Ischemic retinovascular diseases
- glaucomatocyclitic crisis
Additional Information
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- DOID:1685
- rdf-schema#label
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- owl#deprecated
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- http://www.w3.org/2002/07/owl#Class
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- https://w3id.org/def/predibionto#has_symptom_9408
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