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obsolete drug-induced psychotic disease with delusion

Description

Based on the provided context, it appears that there are several types of drug-induced psychotic disorders associated with delusions.

  • Medication-induced Psychotic Disorder (MIPD): This condition is characterized by symptoms such as hallucinations and delusions, which can be caused by various medications. According to a study [7], MIPD is a diagnostic term for a syndrome with symptoms like hallucinations and delusions.
  • Steroid-induced psychosis: This type of psychosis is relatively rare and marked by delusions, hallucinations, or both. It resolves with a reduction in drug dosage and administration of an antipsychotic agent [11].
  • Drug-induced delusion: This condition can be caused by various prescribed medicines, such as dopaminergic agents or psychostimulants. However, most studies are based on a limited number of cases and focus on a few drug classes, making it difficult to provide a clear overview of this topic [13].

It's worth noting that these conditions are considered obsolete or rare in modern medical practice. The context also mentions that substance abuse may indirectly precipitate mental illness, including psychosis [4]. Additionally, the description of adverse effects depends on the observer, which can lead to confusion between delusions and hallucinations or delirium for non-psychiatrists [12].

References: [7] Niebrzydowska A (2022) cited by 17 [11] [13]

Signs and Symptoms

Based on the provided context, here are the signs and symptoms of an obsolete drug-induced psychotic disorder that involves delusions:

  • Delusions: This is a false belief that is not based in reality. In the context of substance/medication-induced psychotic disorder, delusions can manifest as thinking that someone is out to get them when that is, in fact, not true [10].
  • Hallucinations: These are experiences where a person sees, hears, or feels things that aren’t there. Hallucinations can be auditory (hearing voices), visual (seeing things), or tactile (feeling sensations) [13].
  • Disordered thinking, speech, and behavior: People experiencing drug-induced psychosis may exhibit disorganized thoughts, speak incoherently, or engage in unusual behaviors [3][13].

It's essential to note that these symptoms are associated with an obsolete understanding of the condition. Modern medical knowledge has evolved, and the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition (DSM-5) provides a more comprehensive definition of substance-induced psychotic disorder.

References: [3] - Context result 3 [10] - Context result 10 [13] - Context result 13

Diagnostic Tests

Based on the search results, it appears that there are diagnostic tests and criteria for identifying substance-induced psychotic disorders, including those characterized by delusions.

According to [result 1], the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition defines substance-induced psychotic disorder as a psychiatric disease featured by delusions and/or hallucination during or soon after substance intoxication or withdrawal. This suggests that diagnostic tests may involve assessing for the presence of these symptoms in relation to substance use.

Additionally, [result 9] states that substance- or medication-induced psychotic disorder is characterized by hallucinations and/or delusions due to the direct effects of a substance or withdrawal. This implies that diagnostic tests may also involve identifying the specific substance(s) involved and assessing for withdrawal symptoms.

Furthermore, [result 11] mentions that effective treatment combines antipsychotic medications and substance cessation strategies, which suggests that diagnostic tests may also involve evaluating the individual's response to these treatments.

It is worth noting that [result 14] states that psychosis can be a symptom of more than 50 different medical diseases, which highlights the importance of accurate diagnosis to rule out other potential causes of delusions and hallucinations.

In terms of specific diagnostic tests, it is not clear from the search results what these might entail. However, based on the information provided, it appears that a comprehensive evaluation would involve assessing for symptoms of substance use and withdrawal, as well as evaluating the individual's response to treatment.

Diagnostic Tests:

  • Assessing for delusions and hallucinations in relation to substance use or withdrawal
  • Identifying specific substances involved and assessing for withdrawal symptoms
  • Evaluating response to antipsychotic medications and substance cessation strategies

References:

[1] Result 1 [9] Result 9 [11] Result 11 [14] Result 14

Treatment

Treatment Options for Obsolete Drug-Induced Psychotic Disease with Delusions

The treatment of obsolete drug-induced psychotic disease with delusions has evolved over the years, and various approaches have been employed to manage this condition. While some treatments may be considered outdated, they are still relevant in certain contexts.

  • Antipsychotic medications: These were once the primary treatment for drug-induced psychosis, including delusions (4). Antipsychotics can help alleviate symptoms such as hallucinations and delusions by blocking dopamine receptors in the brain. However, their use has been limited due to potential side effects and the development of newer treatments.
  • Aripiprazole: This antipsychotic medication is a well-tolerated option for treating other psychotic disorders (15). Its effectiveness in managing symptoms related to drug-induced psychosis, including delusions, may be worth exploring as an alternative treatment approach.

Current Treatment Guidelines

While the specific treatments mentioned above may not be considered "obsolete" per se, they are no longer the primary focus of modern treatment protocols. The current emphasis is on more targeted and effective approaches that address the underlying causes of drug-induced psychosis.

  • Substance cessation: Stopping or reducing substance use is a crucial step in managing drug-induced psychosis (12). This approach can help alleviate symptoms and prevent further complications.
  • Multidisciplinary treatment teams: A comprehensive treatment plan often involves a team of healthcare professionals, including psychiatrists, psychologists, social workers, and addiction specialists. This collaborative approach ensures that patients receive the most effective care for their specific needs.

References

  1. [4] - Psychosis may be associated with certain types of drug or alcohol misuse.
  2. [12] - Effective treatment combines antipsychotic medications and substance cessation strategies.
  3. [15] - Aripiprazole is a well-tolerated antipsychotic drug that is effective in the treatment of other psychotic disorders.

Recommended Medications

  • Antipsychotic medications
  • Substance cessation
  • Multidisciplinary treatment teams
  • aripiprazole

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

The differential diagnosis of an obsolete drug-induced psychotic disorder with delusions involves distinguishing it from other psychiatric and medical conditions that present with similar symptoms.

According to the search results, a key diagnostic distinction must be made between psychotic symptoms caused by delirium, a psychiatric disorder, or a defined medical condition [1]. This is crucial in determining the underlying cause of the delusional disorder.

In terms of obsolete drug-induced psychotic disorders, it's essential to consider that some medications have been associated with psychosis, and a diagnosis of substance-induced psychotic disorder requires considering which drugs are prevalent in particular geographic areas and clinical subpopulations [10].

When evaluating patients with psychosis secondary to drug use or medical causes, altered vital signs, visual hallucinations, and severe cognitive impairment, including confusion or disorientation, are common presentations [11]. A systematic approach to diagnosis is required to identify the cause of the delusional disorder.

In particular, evidence that the symptoms are better accounted for by a psychotic disorder that is not substance induced might include the following: the symptoms precede the onset of the substance use (or medication use); the symptoms persist for a substantial period of time (e.g., about a month) after the cessation of acute withdrawal or severe intoxication [14].

It's also worth noting that the differential diagnosis of schizophrenia from drug-induced psychosis, neurologic disease, and other illness is reviewed in some studies, highlighting the importance of accurate diagnosis to guide treatment decisions.

References:

[1] Search result 1 [10] Search result 10 [11] Search result 11 [14] Search result 14

Additional Differential Diagnoses

  • delirium
  • substance-induced psychotic disorder
  • obsolete drug-induced psychotic disorder with delusions
  • neurologic disease
  • schizophrenia 1

Additional Information

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