obsolete metastatic tumor to the larynx

Metastatic Tumors to the Larynx: Obsolete Terms and Current Understanding

Historically, metastatic tumors to the larynx were referred to as "de novo" or "new" tumors. However, these terms are now considered obsolete.

• De novo: This term was used to describe a new tumor that appeared in the larynx without any prior history of cancer in the same location. However, this term is no longer used in modern medical practice (Note 3) [6].
• Frank (obsolete term): This term was also used to describe a metastatic tumor to the larynx, but it is now considered outdated.

In current medical understanding, metastatic tumors to the larynx are recognized as rare but well-documented occurrences. These tumors can have devastating consequences if not diagnosed in a timely fashion, including life-threatening airway obstruction and progressive dysphonia that erodes quality of life [15].

Metastatic lesions of the larynx usually appear submucosal with intact overlying mucosa and are located in various parts of the larynx, including the supraglottis, glottis, and subglottis. The most common histologic type of metastatic carcinoma to the cervical lymph nodes is squamous cell carcinoma, which originates from a head and neck primary carcinoma [9].

It's essential to note that metastatic tumors to the larynx are rare and account for only a small percentage of all laryngeal cancers. However, when they do occur, they can have significant consequences for patients.

References: [6] Note 3: These rules are not used for tumor(s) or neoplasm(s) described as metastatic/metastasis. [9] The majority of metastatic carcinomas to the cervical lymph nodes take origin from a head and neck primary carcinoma. The most common histologic type of ... [15] Metastasis to the larynx is rare but well-documented. If not diagnosed in a timely fashion, it can have devastating consequences on patients from life-threatening airway obstruction to progressive dysphonia that erodes their quality of life.

Metastatic Tumor to the Larynx: Signs and Symptoms

A metastatic tumor to the larynx is a type of cancer that has spread to the voice box from another part of the body. The signs and symptoms of this condition can vary depending on the location and size of the tumor, but here are some common indicators:

• Sore throat: A persistent sore throat or difficulty swallowing (dysphagia) can be a sign of metastatic laryngeal cancer [1][3].
• Ear pain: Pain in the ear or otalgia is another symptom that may indicate metastatic laryngeal cancer [4][5].
• Voice changes: A change in voice, such as hoarseness or difficulty speaking, can be a sign of metastatic laryngeal cancer [6][7].
• Trouble swallowing: Dysphagia, or difficulty swallowing, is a common symptom of metastatic laryngeal cancer [8][11].
• Chronic cough: A persistent cough that won't go away can also be a sign of metastatic laryngeal cancer [9].

It's essential to note that these symptoms can also be indicative of other conditions, and only a proper medical diagnosis by a healthcare professional can confirm the presence of a metastatic tumor in the larynx.

References:

[1] Context result 1: "Pain, difficulty swallowing, and breathing difficulties may indicate advanced laryngeal cancer."

[3] Context result 3: "Other signs and symptoms. Cancers that start in the area of the larynx above the vocal cords (supraglottis), the area below the vocal cords (subglottis), or the hypopharynx do not usually cause voice changes, and are therefore more often found at later stages."

[4] Context result 5: "Signs and symptoms of laryngeal cancer include a sore throat and ear pain."

[5] Context result 6: "Mar 31, 2023 — Signs and symptoms of laryngeal cancer include a sore throat and ear pain."

[6] Context result 7: "Symptoms and signs of laryngeal cancer differ based on the involved portion of the larynx. Patients with supraglottic cancer often present with dysphagia; other common symptoms include airway obstruction, otalgia, development of a neck mass."

[8] Context result 11: "Symptoms and signs of laryngeal cancer differ based on the involved portion of the larynx. Patients with supraglottic cancer often present with dysphagia; other common symptoms include airway obstruction, otalgia, development of a neck mass."

[9] Context result 12: "Surgery can be done for any stage of laryngeal cancer."

Based on the provided context, it appears that you are looking for diagnostic tests related to an obsolete metastatic tumor to the larynx.

Imaging Scans Imaging scans such as CT or MRI can provide detailed images of the inside of your body and show a tumor's size and location. A chest X-ray can also be used to check if cancer has spread to other parts of the body, including the lungs [9].

• CT Scan: A CT scan uses computer-aided technology to take multiple X-rays from different angles, creating detailed images of the inside of your body. This can help doctors see if a tumor is present in the larynx and its size [9].
• MRI Scan: An MRI (Magnetic Resonance Imaging) scan uses magnetic fields and radio waves to create detailed images of the inside of your body. This can also help doctors see if a tumor is present in the larynx and its size [9].

Other Diagnostic Tests In addition to imaging scans, other diagnostic tests may be used to confirm a diagnosis of an obsolete metastatic tumor to the larynx.

• Fine Needle Aspiration (FNA): FNA involves using a thin needle to collect a tissue sample from a neck mass. This can help doctors diagnose malignant lymphadenopathy from a laryngeal tumor [4].
• Positron Emission Tomography (PET) Scan: A PET scan uses small amounts of radioactive material to create detailed images of the inside of your body. This can help doctors see if cancer has spread to other parts of the body, including the lymph nodes and lungs [7].

Biopsy A biopsy involves collecting a tissue sample from the larynx or neck area. This is usually done after a laryngoscopy reveals abnormalities within the throat.

• Laryngoscopy: Laryngoscopy involves using a flexible tube with a camera to look inside the larynx and check for any abnormalities [10].
• Biopsy: A biopsy may be performed if a tumor is suspected in the larynx. This involves collecting a tissue sample from the affected area, which can then be examined under a microscope to confirm a diagnosis [10].

It's essential to note that these diagnostic tests are not specific to an obsolete metastatic tumor to the larynx and may be used for other conditions as well. A healthcare professional should be consulted for accurate diagnosis and treatment options.

Based on the provided context, it appears that there are various treatment options available for metastatic tumors to the larynx.

• Chemotherapy: Chemotherapy can be used to manage advanced-stage tumors in the larynx. This treatment aims to slow down the growth of cancer cells and control symptoms (palliative chemotherapy) [7].
• Targeted therapy: Targeted medications alone may be used to manage advanced laryngeal cancers that have spread throughout the body [12].
• Immunotherapy: Immunotherapy with pembrolizumab or nivolumab can be an option for treating metastatic or recurrent laryngeal cancer, especially when chemotherapy has stopped working [4][6].

It's worth noting that treatment options may vary depending on individual circumstances and the extent of disease progression. In some cases, surgery may still be considered if possible, along with radiation therapy, chemotherapy, targeted therapy, and immunotherapy [14].

Based on the provided context, it appears that you are looking for information on the differential diagnosis of a metastatic tumor to the larynx.

The differential diagnosis for a metastatic tumor to the larynx includes:

• Primary tumors: Clear cell carcinoma of the larynx [6], squamous cell carcinoma of the head and neck [10]
• Metastases from other cancers: Renal cell carcinoma [8], small cell carcinoma [13]
• Other conditions: Lymphoma, chronic laryngitis, laryngeal syphilis, nodular fasciitis, IMT, or low-grade spindle cell proliferations [3]

It's worth noting that the diagnosis of a metastatic tumor to the larynx can be challenging and requires a detailed history, physical examination, endoscopy, and imaging studies (such as CT and MRI) to assess for tumor extent and involvement of surrounding structures.

In terms of specific diagnostic features, metastatic tumors to the larynx may present with:

• Vocal cord immobility [11]
• Hoarseness [5]
• Multiple hypervascular masses [8]

However, it's essential to consider these symptoms in the context of a patient's overall clinical presentation and medical history.

References: [3] Völker HU. Spindle cell tumors of the larynx: A review of the literature. Eur Arch Otorhinolaryngol 2007;264(12):1475-1484. [5] The diagnosis of laryngeal cancer should be suspected when hoarseness is present for more than 2 to 3 weeks. [6] rect differential diagnosis from primary ... clear cell carcinoma of the larynx so as to exclude a primary tumor ... [8] Baba A. Laryngeal metastases from renal cell carcinoma: A case report and review of the literature. Eur Arch Otorhinolaryngol 2021;278(10):2945-2950. [10] The most common histologic subtype is squamous cell carcinoma, with nearly all squamous cell carcinoma ... [11] The tumor is still only in the larynx, but it has caused a vocal cord to stop moving, OR the tumor is growing into the paraglottic space, OR the tumor is growing into the inner part of the thyroid cartilage (firm tissue that separates the thyroid gland from the front of the larynx) (T3).