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benign prostate phyllodes tumor
Description
Based on the search results, here is a description of Benign Prostate Phyllodes Tumor:
What is it?
Benign Prostate Phyllodes Tumor (BPT) is a rare and unusual type of tumor that affects the prostate gland. It is also known as cystic epithelial-stromal tumor or phyllodes type of atypical hyperplasia.
Characteristics:
- A biphasic tumor, meaning it has both stromal and epithelial components
- Forms cysts lined by hyperplastic epithelium in a cellular or sarcomatoid stroma
- Can be clinically benign or malignant
- Tends to recur after transurethral resection
Symptoms:
- Obstructive voiding symptoms (difficulty urinating)
- Dysuria (painful urination)
- Hematuria (blood in the urine)
Prognosis:
- Generally considered a low-grade tumor with minimal metastatic potential
- However, if not completely resected, even low-grade tumors can cause recurrent obstructive symptoms
Treatment:
- Surgical removal of the tumor is usually recommended
- Transurethral resection (TUR) may be performed to remove the tumor
Please note that this information is based on a limited number of search results and may not be comprehensive or up-to-date. If you have any specific questions or concerns, I'll do my best to help!
Additional Characteristics
- Hematuria (blood in the urine)
- Dysuria (painful urination)
- Biphasic tumor with both stromal and epithelial components
- Forms cysts lined by hyperplastic epithelium in a cellular or sarcomatoid stroma
- Can be clinically benign or malignant
- Tends to recur after transurethral resection
- Obstructive voiding symptoms (difficulty urinating)
- Generally considered a low-grade tumor with minimal metastatic potential
- Surgical removal of the tumor is usually recommended
- Transurethral resection (TUR) may be performed to remove the tumor
Signs and Symptoms
Based on the context provided, here are the signs and symptoms of benign prostate phyllodes tumor:
- Urinary obstructive symptoms: This is the most common presenting sign, which can include difficulty starting or stopping urine flow, weak urine stream, frequent urination, and urinary retention.
- Hematuria (blood in urine): Microscopic or macroscopic hematuria may be present, which can range from a small amount of blood to a significant amount.
- Abdominal pain and distention: Some patients may experience abdominal pain and swelling due to the tumor's size and location.
- Dysuria (painful urination): This symptom can occur due to the tumor's presence in the prostate gland.
- Urinary retention: In some cases, the tumor can cause complete urinary retention, requiring catheterization or other interventions.
- Palpable abdominal mass: A palpable lump may be felt in the abdomen, which is usually a sign of an enlarged prostate due to the tumor.
It's essential to note that these symptoms can also be present in other conditions, such as benign prostatic hyperplasia (BPH) or prostate cancer. Therefore, a proper diagnosis by a healthcare professional is necessary for accurate identification and treatment of benign prostate phyllodes tumor.
Additional Symptoms
- Dysuria (painful urination)
- Frequent urination
- Abdominal pain and distention
- Hematuria (blood in urine)
- Weak urine stream
- Difficulty starting or stopping urine flow
- abdominal mass
- urinary retention
Diagnostic Tests
Treatment
Based on the provided context, it appears that there are limited treatment options for benign prostate phyllodes tumors, and most information available is related to malignant cases.
However, according to search result [11], benign phyllodes tumour (BPT) of the prostate is a very rare neoplasm. It is composed of hyperplastic and neoplastic glandular stromal proliferation. In addition, endocrine therapies, including anti-androgen agents, can be used in the treatment of phyllodes tumors of the prostate [1, 4].
It's worth noting that most information available on the context is related to malignant cases, and there seems to be a lack of specific guidance on treating benign prostate phyllodes tumors.
Some possible treatment options for benign prostate phyllodes tumors may include:
- Endocrine therapies, such as anti-androgen agents
- Surgical excision with a clear margin (as mentioned in search result [14])
- Monitoring and observation, given the low recurrence rate of benign tumors (7.1% as per search result [15])
However, it's essential to consult with a healthcare professional for personalized advice on treating benign prostate phyllodes tumors.
References:
[1] by Y Murakami · 2014 · Cited by 6 [4] by P KARIHTALA · 2016 · Cited by 9 [11] Benign phyllodes tumour (BPT) of the prostate is a very rare neoplasm. [14] Surgical excision with a clear margin is the standard treatment for phyllodes tumors. [15] The pooled estimated recurrence rates of benign, borderline, and malignant tumors were 7.1%, 16.7%, and 25.1%.
Recommended Medications
- Endocrine therapies
- anti-androgen agents
💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.
Differential Diagnosis
The differential diagnosis for benign prostate phyllodes tumors involves several conditions that can present similarly in terms of symptoms and imaging characteristics. Here are some of the key considerations:
- Prostatic cystadenocarcinoma: This is a type of cancer that can present as a large cystic mass, similar to a phyllodes tumor. It's essential to differentiate between these two conditions through biopsy.
- Benign prostatic hyperplasia (BPH) nodules: BPH nodules can sometimes be mistaken for phyllodes tumors due to their similar appearance on imaging studies. However, BPH nodules are typically smaller and more localized than phyllodes tumors.
- Adenocarcinoma: This type of prostate cancer can also present as a solid or cystic mass, making it challenging to differentiate from a phyllodes tumor based solely on imaging characteristics.
- Sarcomas and other mesenchymal lesions: Phyllodes tumors are rare in the prostate, but when they occur, they can be confused with sarcomas or other types of mesenchymal lesions. A thorough histopathological examination is necessary to rule out these conditions.
According to [6], the differential diagnosis for phyllodes tumor
Additional Differential Diagnoses
- Sarcomas and other mesenchymal lesions
- Prostatic cystadenocarcinoma
- Benign prostatic hyperplasia (BPH) nodules
- adenocarcinoma
Additional Information
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.