obsolete intramucosal adenocarcinoma colon adenoma

Based on the search results, I was able to find some relevant information about the signs and symptoms of colorectal cancer, which may be applicable to intramucosal adenocarcinoma colon adenoma.

Common symptoms:

• Change in bowel habits, such as more frequent diarrhea or constipation [8][9]
• Rectal bleeding or blood in the stool [7][9]

Other possible symptoms:

• Abdominal pain [5][6]
• Fatigue [5]
• Unexplained weight loss [9]

It's worth noting that many people with colorectal cancer do not have any symptoms in the early stage of the disease, which is why screening and regular check-ups are important for early detection.

Specific to mucinous adenocarcinoma:

Mucinous adenocarcinomas (MACs) are a type of cancerous tumor that forms in the epithelial tissue. While specific symptoms may not be well-documented for intramucosal adenocarcinoma colon adenoma, MACs have been associated with:

• Mucus production and secretion [11]
• Tumors often found in colorectal cancer, but also in other glandular organs [11]

Please keep in mind that these are general symptoms and may not be specific to intramucosal adenocarcinoma colon adenoma. If you have any further questions or would like more information, feel free to ask.

References: [5] by EJ Kuipers · 2015 · Cited by 229 [6] Sep 6, 2024 [7] The presence of blood in stools can be a sign of colorectal cancer or of a polyp. [8] Mar 24, 2015 — Signs and Symptoms. Unfortunately, most people with colorectal cancer do not have any symptoms in the early stage of the disease. [9] Black, tar-like stools · Blood during a bowel movement · Change in bowel habits · Unexplained weight loss [11] Mucinous adenocarcinomas, also known as MACs, are a type of cancerous tumor that forms in the epithelial tissue.

Based on the provided context, it appears that you are looking for diagnostic tests for a specific type of cancer, namely intramucosal adenocarcinoma in the colon.

Diagnostic Tests

The following diagnostic tests can be used to detect and diagnose intramucosal adenocarcinoma in the colon:

• Colonoscopy: This is a procedure where a flexible tube with a camera and light on the end (colonoscope) is inserted through the rectum to visualize the inside of the colon. Colonoscopy can help identify polyps, tumors, or other abnormalities in the colon lining [9].
• Biopsy: A biopsy involves taking a small sample of tissue from the suspicious area using a special instrument called a biopsy forceps. The tissue is then examined under a microscope for cancer cells [11].
• Imaging tests: Imaging tests such as CT scans, MRI, or PET scans may be used to help stage the cancer and determine its extent [7].

Important Considerations

It's essential to note that intramucosal adenocarcinoma is not the same as colon cancer. While it's a type of cancer, it cannot spread beyond the mucosa layer. However, if left untreated, it can progress to invasive carcinoma.

Additional Information

The adenoma-carcinoma pathway is considered responsible for the majority of colorectal cancers [12]. Fecal immunochemical tests (FITs) have been used for CRC screening in several countries and may also be useful in detecting advanced adenomas and CRCs [12].

References:

[9] TS Suhardja, 2020 - In the colorectum, invasion of the submucosa is required to diagnose an invasive carcinoma.

[11] Intramucosal carcinoma on biopsy reliably predicts invasive colorectal cancer. MacDonald AW, Tayyab M, Arsalani-Zadeh R, Hartley JE, Monson JR. Ann Surg Oncol. 2009 Dec;16(12):3267-70.

[7] by R Labianca · 2013 - Endoscopy is the main procedure for diagnosis and can be carried out by either sigmoidoscopy (as >35% of tumours are located in the rectosigmoid) or (preferably) colonoscopy.