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benign epilepsy with centrotemporal spikes
Description
Benign Epilepsy with Centrotemporal Spikes (BECTS): An Overview
Benign Epilepsy with Centrotemporal Spikes, also known as Benign Rolandic Epilepsy (BRE) or Childhood Epilepsy with Centrotemporal Spikes (CECTS), is a common type of epilepsy syndrome affecting children. This condition is characterized by seizures that originate in the centrotemporal region of the brain, which controls movements.
Key Features:
- Age-dependent: BECTS typically starts between 4-10 years old and resolves spontaneously before adolescence.
- Focal seizures: Seizures affect one side of the face or mouth, often involving unilateral facial sensory-motor symptoms.
- Benign course: Most children outgrow this condition by puberty, with a very good outcome and minimal long-term treatment required.
Statistics:
- Accounts for 6-7% of all childhood epilepsy cases (Source: [5])
- Affects approximately 15-20% of all childhood epilepsies (Source: [13])
Symptoms:
- Brief, mostly nocturnal motor seizures involving unilateral face and arm
- Seizures tend to affect one side of the child's face or mouth
Treatment:
- Majority of patients may avoid long-term treatment due to the mild course and good outcome.
- Treatment is usually not necessary as children outgrow this condition by adolescence.
References:
[1] [10] [2] [11] [3] [12] [4] [13] [5] [6] [7] [14] [8] [15]
Additional Characteristics
- A common type of epilepsy syndrome affecting children
- Seizures affect one side of the face or mouth, often involving unilateral facial sensory-motor symptoms
- Most children outgrow this condition by puberty with a very good outcome and minimal long-term treatment required
- Brief, mostly nocturnal motor seizures involving unilateral face and arm
- Seizures tend to affect one side of the child's face or mouth
Signs and Symptoms
Diagnostic Tests
Diagnostic Tests for Benign Epilepsy with Centrotemporal Spikes (BECTS)
Benign epilepsy with centrotemporal spikes (BECTS), also known as rolandic epilepsy, is a type of childhood epilepsy that can be diagnosed through various tests. The following diagnostic tests are commonly used to confirm the presence of BECTS:
- **Elect
Additional Diagnostic Tests
- Magnetic Resonance Imaging (MRI)
- Electroencephalogram (EEG)
Treatment
Overview of Drug Treatment for Benign Epilepsy with Centrotemporal Spikes (BECTS)
Benign epilepsy with centrotemporal spikes (BECTS), also known as Rolandic epilepsy, is a common childhood epilepsy syndrome. While most children outgrow these seizures by adolescence, some may require medication to manage their symptoms.
Commonly Prescribed Medications
Several antiepileptic drugs (AEDs) are commonly used to treat BECTS, including:
- Levetiracetam: This medication is often prescribed as a first-line treatment for BECTS [1][2].
- Valproic acid: This AED may be considered the drug of choice in some cases [9].
- Oxcarbazepine: This medication can also be used to treat BECTS, particularly if other AEDs are not effective [7].
Treatment Guidelines
While there is no specific treatment guideline for BECTS, several countries recommend the following first-line drugs:
- Levetiracetam
- Carbamazepine
- Sodium valproate
- Oxcarbazepine
- Lamotrigine
It's essential to note that not all children with BECTS require medication. Some may be able to manage their symptoms without treatment [13].
Importance of Compliance
If drug treatment is undertaken, it's crucial for the family/patient to understand the need for compliance and regular monitoring to ensure the best possible outcomes [11].
References:
[1] Kessi, M. (2021). Prescribing Practices and Antiepileptic Drug Choice in Benign Epilepsy with Centrotemporal Spikes (2646).
[2] Hull, M., Stowe
Differential Diagnosis
Benign epilepsy with centrotemporal spikes (BECTS) can be challenging to diagnose, as it shares similar characteristics with other conditions. To establish a correct diagnosis, it's essential to rule out other potential causes.
Conditions to consider in the differential diagnosis of BECTS:
- Rolandic spikes and no seizures: This condition is often characterized by the presence of rolandic spikes on EEG without any associated seizures (Source: [5]). It's crucial to differentiate between this condition and BECTS, as they share similar EEG patterns.
- Benign childhood epilepsy with centrotemporal spikes vs. MTLE: Both conditions can begin in childhood with generalized seizures, making differential diagnosis essential (Source: [7]).
- Other focal epilepsies: BECTS should be differentiated from other types of focal epilepsies, such as frontal lobe epilepsy or temporal lobe epilepsy, which may present with different seizure characteristics and EEG patterns.
Key factors to consider in the differential diagnosis:
- Age of onset: BECTS typically presents between 4-10 years (range 3-14 years), whereas other conditions may have different age ranges (Source: [4]).
- Seizure characteristics: The presence of partial seizures with motor signs, frequently associated with somatosensory symptoms, is a hallmark of BECTS (Source: [3]). However, other conditions may present with similar seizure characteristics.
- EEG patterns: While rolandic spikes are characteristic of BECTS, other conditions may also exhibit similar EEG patterns.
Accurate diagnosis requires a comprehensive evaluation
To accurately diagnose BECTS, it's essential to consider the patient's medical history, perform a thorough physical examination, and conduct diagnostic tests such as EEG and imaging studies. A correct diagnosis can help guide treatment decisions and improve patient outcomes.
References:
[1] Source: [9] [2] Source: [10] [3] Source: [6] [4] Source: [4] [5] Source: [5] [6] Source: [11] [7] Source: [7] [8] Source: [8] [9] Source: [9] [10] Source: [10] [11] Source: [11] [12] Source: [12] [13] Source: [13] [14] Source: [14] [15] Source: [15]
Additional Differential Diagnoses
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:3329
- core#notation
- DOID:3329
- oboInOwl#hasDbXref
- UMLS_CUI:C0376532
- IAO_0000115
- A childhood electroclinical syndrome characterized by partial seizures involving the rolandic area of the brain and electroencephalographic centrotemporal sharp waves.
- oboInOwl#hasExactSynonym
- sylvan seizures
- rdf-schema#label
- benign epilepsy with centrotemporal spikes
- rdf-schema#subClassOf
- t423464
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/doid#DO_rare_slim
- RO_0002488
- http://purl.obolibrary.org/obo/HP_0011463
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_10266
- owl#annotatedSource
- t423436
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