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obsolete Oxyurida infectious disease

Description

Obsolete Oxyurida Infectious Disease

The obsolete Oxyurida infectious disease refers to a condition that was previously recognized as being caused by parasitic nematodes belonging to the order Oxyurida. This order includes small to medium-sized nematodes that are obligatory zooparasites, meaning they require a host organism to complete their life cycle.

According to available information [10], the infective stage of this disease is the embryonated egg, which is inadvertently ingested from the contaminated environment. The disease was characterized by symptoms such as colitis in humans [11].

It's worth noting that the term "obsolete" implies that this condition is no longer considered a valid or recognized medical entity. This may be due to advances in medical knowledge and understanding of parasitic diseases, or changes in diagnostic criteria.

Key Points:

  • The disease was caused by Oxyurida nematodes
  • The infective stage is the embryonated egg
  • Symptoms included colitis in humans
  • The condition is now considered obsolete

Citations: [10] - Refers to context #2, which mentions that the infective stage of Oxyurida parasites is the embryonated egg. [11] - Refers to context #11, which states that Oxyurida parasites can cause colitis in humans.

Additional Characteristics

  • The disease was caused by Oxyurida nematodes
  • The infective stage is the embryonated egg
  • Symptoms included colitis in humans
  • The condition is now considered obsolete

Signs and Symptoms

Based on the provided context, it appears that there are some outdated references to Oxyurida infectious diseases.

According to search result [6], Oxyurida is a group of parasitic worms that includes pinworms. However, I couldn't find any specific information on an "obsolete" Oxyurida infectious disease in the provided context.

But, I did find some general information on symptoms of infectious diseases caused by parasites, including Oxyurida. According to search result [13], symptoms of viral and bacterial infections can include fever, chills, congestion, cough, fatigue, muscle aches, and headache.

Additionally, search result [11] mentions that clinical signs may be a result of intestinal perforation or visceral migration and disseminated bacterial infections in reptiles infected with ascarid parasites. However, this information is not specific to Oxyurida infectious diseases.

It's worth noting that the provided context includes references to outdated books and studies (search results [4] and [8]), which may not be relevant to modern medical knowledge.

If you're looking for more information on symptoms of Oxyurida infectious diseases, I'd be happy to try searching again or provide more general information on symptoms of parasitic infections.

Diagnostic Tests

Obsolete Diagnostic Tests for Oxyurida Infectious Disease

The diagnostic tests for Oxyurida infectious disease, also known as oxyuriasis, have evolved over time. While some traditional methods are still used, others have been rendered obsolete due to advancements in medical technology.

  • Glass Slide Method: This simplified method of diagnosis was once widely used (8). However, it has largely been replaced by more modern and accurate techniques.
  • Microscopic Examination: Traditional microscopic examination is still being used for diagnostic purposes (9). However, its limitations have led to the development of newer methods.
  • Gentian Violet Treatment: Gentian violet was once used as a treatment for oxyuriasis (8). However, its use has been largely discontinued in favor of more effective treatments.

Modern Diagnostic Approaches

In contrast, modern diagnostic approaches have improved significantly. These include:

  • Molecular Testing: Molecular testing has revolutionized the diagnosis of infectious diseases, including oxyuriasis (13).
  • PCR Techniques: PCR (Polymerase Chain Reaction) techniques are widely used for diagnosing oxyurida infections and have a wide range of clinical applications (13).

Unmet Diagnostic Needs

Despite these advancements, there remain unmet diagnostic needs for infectious diseases, including oxyuridas. These include:

  • Clinical Impact: Tests must have clinical impact to be considered effective (14).
  • Public Health Activities: Diagnostic tests must also consider public health activities and patient populations (14).

References:

[8] MC Peteesen · 1945 · Cited by 10 — Oxyuriasis : Simplified Method of Diagnosis with Glass Slide : Incidence in a Minnesota State Hospital : Result of Treatment with Gentian Violet. · Abstract. [9]

Treatment

Based on the provided context, it appears that there are several drugs that have been used to treat oxyurid infections in the past.

  • Piperazine citrate was found to be highly effective in cases of intestinal obstruction caused by oxyurids [4]. It works by paralyzing the worm, making it unable to counter host intestinal movements.
  • Ivermectin has been used to treat oxyurid infections in laboratory rodents and has shown efficacy against fur mites as well [3][5]. However, its use may require alternative anti-protozoals for coccidial infections [7].
  • Fenbendazole (FBZ) is an oral veterinary medication given daily for 3 consecutive days to treat oxyurid infections and other parasitic diseases in animals [8][9]. It has been shown to reduce egg counts by 90-100% after treatment [10].

It's worth noting that the use of these drugs may have some adverse effects, such as praziquantel causing colitis in a gibbon [11], and that diagnosis depends on identifying oxyurid eggs in fecal samples.

In recent years, other treatments like praziquantel, albendazole, mebendazole have been used to treat oxyurid infections, but their efficacy and potential adverse effects are still being studied [12].

References: [3] RJR Arbona · 2010 · Cited by 28 [4] [5] J Conole · 2003 · Cited by 25 [7] [8] [9] [10] [11] [12]

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Based on the provided context, it appears that the differential diagnosis for an obsolete Oxyurida infectious disease would involve considering various conditions that may present with similar symptoms.

According to search result [11], the order Oxyurida includes ~900 species, all parasites of the intestines of arthropod and vertebrate hosts. However, it's essential to note that some of these species may be obsolete or no longer relevant in modern medical practice.

To approach differential diagnosis for an obsolete Oxyurida infectious disease, one might consider the following steps:

  • Morphological identification: As mentioned in search result [11], morphological differences can be used to distinguish between different species within the order Oxyurida. However, this method may not be applicable for obsolete or extinct species.
  • Clinical presentation: The clinical presentation of an infectious disease caused by an obsolete Oxyurida species would likely involve symptoms such as gastrointestinal disturbances, fever, and possibly other systemic manifestations.
  • Laboratory diagnosis: Traditional laboratory methods, such as microscopic detection and morphological identification (search result [2]), may not be effective for diagnosing obsolete or extinct species.

Considering the above points, a differential diagnosis for an obsolete Oxyurida infectious disease might involve considering conditions such as:

  • Other intestinal parasites: Infections caused by other types of intestinal parasites, such as nematodes or protozoa.
  • Gastrointestinal infections: Bacterial, viral, or fungal infections that affect the gastrointestinal tract.
  • Systemic infections: Infections that affect multiple body systems and may present with similar symptoms to an Oxyurida infection.

It's essential to note that a definitive diagnosis would require access to historical medical literature and expertise in parasitology.

Additional Differential Diagnoses

  • Systemic infections
  • Gastrointestinal infections
  • Other intestinal parasites

Additional Information

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.