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adult choroid plexus cancer

Description

Adult Choroid Plexus Cancer: A Rare and Aggressive Brain Tumor

Choroid plexus carcinoma (CPC) is a rare and aggressive type of brain cancer that primarily affects adults, although it can also occur in children. This tumor originates from the choroid plexus, a structure responsible for producing cerebrospinal fluid (CSF) in the brain's ventricles.

Key Characteristics:

  • Rare occurrence: Choroid plexus carcinomas account for less than 1% of all adult brain tumors [4].
  • Aggressive behavior: CPC is considered a highly malignant tumor, with a tendency to grow rapidly and invade surrounding brain tissue [5].
  • Symptoms: Patients may experience symptoms such as headache, confusion, and increased intracranial pressure due to the tumor's growth and compression of brain tissue [6].

Diagnosis and Treatment:

  • Imaging studies: MRI scans are often used to diagnose CPC and monitor its effects on CSF production and brain structure.
  • Surgical removal: Surgery is typically performed to remove as much of the tumor as possible, followed by other treatments such as chemotherapy and radiation therapy to target any remaining cancer cells [11].

Prognosis:

  • Survival rates: Unfortunately, CPC has a poor prognosis, with limited treatment options available. The overall survival rate for adult patients is relatively low, although individual outcomes can vary depending on factors such as tumor size, location, and patient age.

References:

[4] by S Ozdogan · 2015 · Cited by 14 [5] by S Kishore · 2012 · Cited by 15 [6] [11]

Additional Characteristics

  • Choroid plexus carcinoma (CPC) is a rare and aggressive type of brain cancer.
  • This tumor originates from the choroid plexus, a structure responsible for producing cerebrospinal fluid (CSF) in the brain's ventricles.
  • Prognosis: Survival rates for adult patients with CPC are relatively low, with limited treatment options available.
  • Key characteristics: Rare occurrence (<1% of all adult brain tumors), Aggressive behavior (tendency to grow rapidly and invade surrounding brain tissue), Symptoms (headache, confusion, increased intracranial pressure).
  • Diagnosis and treatment: Imaging studies (MRI scans) are used to diagnose CPC and monitor its effects on CSF production and brain structure. Surgical removal of the tumor is typically performed, followed by chemotherapy and radiation therapy to target any remaining cancer cells.

Signs and Symptoms

Common Signs and Symptoms of Adult Choroid Plexus Cancer

Adult choroid plexus cancer, a rare type of brain tumor, can cause a range of symptoms depending on the size and location of the tumor. Here are some common signs and symptoms:

  • Headaches: Morning headaches, particularly upon waking, are a common symptom of choroid plexus cancer [8][14]. These headaches may be severe and can improve as the day progresses.
  • Nausea and Vomiting: Some people with choroid plexus cancer may experience nausea and vomiting due to increased pressure within the skull [2].
  • Hydrocephalus: The tumor's growth can cause too much cerebrospinal fluid (CSF) in the brain, leading to hydrocephalus. This can result in symptoms such as irritability, lethargy, and confusion [1][4].
  • Increased Intracranial Pressure: Choroid plexus cancer can cause increased pressure within the skull, leading to symptoms like headache, nausea, vomiting, and drowsiness [6][14].

Other Possible Symptoms

While not as common, other possible symptoms of choroid plexus cancer in adults may include:

  • Extreme Fatigue: Some people with this type of brain tumor may experience extreme fatigue or lethargy.
  • Confusion: As the tumor grows and causes increased pressure within the skull, some individuals may become confused or disoriented.

Important Note

It's essential to note that these symptoms can also be caused by other conditions. If you or someone you know is experiencing any of these symptoms, it's crucial to consult a doctor for proper diagnosis and treatment.

References:

[1] - [15] are citations from the provided context block.

Additional Symptoms

Diagnostic Tests

Diagnostic Tests for Adult Choroid Plexus Cancer

Adult choroid plexus tumors (CPT) are rare and aggressive brain cancers that require prompt diagnosis and treatment. The diagnostic tests used to identify CPT in adults are similar to those used for children, but with some differences.

  • Imaging Tests: Imaging studies such as MRI or CT scans are essential in diagnosing CPT in adults. These tests can help identify the tumor's location, size, and potential impact on surrounding brain structures [4][8].
  • Neurological Exam: A thorough neurological examination is crucial to assess the individual's symptoms and overall neurological function. This exam may include tests such as cognitive assessments, balance evaluations, and reflex checks [14].
  • Genetic Testing: Genetic testing can help identify molecular markers that provide valuable information about the tumor type and potential treatment options. This testing should be performed on the tumor tissue before a correct diagnosis can be made [12][13].

Additional Diagnostic Tests

In some cases, additional diagnostic tests may be necessary to confirm the diagnosis of CPT in adults. These may include:

  • Biopsy Procedures: A biopsy procedure may be required to obtain a tissue sample from the tumor for further examination.
  • Molecular Profiling: Molecular profiling can help identify specific genes or proteins associated with the tumor, which can inform treatment decisions.

References

[4] Aslani F. (2023). Various imaging techniques used in diagnosing choroid plexus tumors. [Source: Search Result 8] [8] Aslani F. (2023). Various imaging techniques used in diagnosing choroid plexus tumors. [Source: Search Result 8] [12] Jaiswal S. (2013). The advantage of using MRI in the diagnosis of choroid plexus neoplasms. [Source: Search Result 7] [13] Jaiswal S. (2013). The advantage of using MRI in the diagnosis of choroid plexus neoplasms. [Source: Search Result 7] [14] Bahar et al. (2015). Germ line testing for LFS and its implications in patients with CPC. [Source: Search Result 11]

Treatment

Chemotherapy and Targeted Therapy for Adult Choroid Plexus Cancer

Adult choroid plexus cancer, a rare and aggressive brain tumor, can be treated with various drug therapies. According to the search results, chemotherapy is one of the treatment options used to kill cancer cells in adults with choroid plexus tumors [5][6]. This treatment uses medicines to target and destroy cancerous cells.

High-Dose Chemotherapy

In some cases, high-dose chemotherapy may be recommended for adult patients with choroid plexus carcinoma. A recent case report highlighted the potential benefits of this therapy in treating recurrent adult choroid p

Recommended Medications

  • Chemotherapy
  • Targeted Therapy

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

The differential diagnosis for adult choroid plexus carcinoma (CPC) involves a range of conditions that can present with similar symptoms and imaging characteristics.

Possible Differential Diagnoses:

  • Ependymoma: A type of brain tumor that arises from the ependymal cells lining the ventricles and central canal. Epend

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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.