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gastric adenocarcinoma

Description

Signs and Symptoms

Diagnostic Tests

Treatment

Chemotherapy, Targeted Therapy, and Immunotherapy for Gastric Adenocarcinoma

Gastric adenocarcinoma, also known as stomach cancer, can be treated with various drug therapies. The most common types of drug treatments are:

  • Chemotherapy: This treatment uses anti-cancer drugs that enter the bloodstream and reach all areas of the body, making it useful for cancer that has spread to organs beyond where it started [13]. Chemotherapy can help people with stomach cancer live longer by killing cancer cells or stopping their growth [7].
  • Targeted Therapy: Targeted drugs can sometimes be used to treat stomach cancer, either alone or along with chemo, depending on the situation [4]. Examples of targeted therapy for stomach cancer include:
    • Trastuzumab (Herceptin) [5]
    • Nivolumab (Opdivo) [6]
    • Pembrolizumab
    • Ramucirumab [3]
  • Immunotherapy: Immunotherapy is a type of treatment that uses the body's immune system to fight cancer. It can be used in combination with chemotherapy and targeted therapy for stomach cancer.

Specific Drug Combinations

Some specific drug combinations have been shown to be effective in treating gastric adenocarcinoma, including:

  • Paclitaxel plus ramucirumab [3]
  • Trastuzumab (Herceptin) plus chemo plus immunotherapy [10]

References:

[1] The list includes generic and brand names. This page also lists common drug combinations used in stomach (gastric) cancer. [2] Chemotherapy is a drug treatment that uses chemicals to kill cancer cells. [3] In the phase 3 REGARD trial, ramucirumab was shown to have a 1.4 month survival benefit compared to placebo in the second line treatment of advanced gastric adenocarcinoma. [4] Targeted drugs can sometimes be used to treat stomach cancer (gastric cancer), either alone or along with chemo, depending on the situation. [5] Types of targeted and immunotherapy cancer drugs for stomach cancer · Trastuzumab (Herceptin) · Nivolumab (Opdivo) · Pembrolizumab · Ramucirumab [6] Chemo plus immunotherapy plus the targeted drug trastuzumab (if the cancer tests positive for HER2 and for the PD-L1 protein), or chemo plus radiation therapy (chemoradiation). [7] Chemotherapy drugs used to ... [10] Stomach adenocarcinoma symptoms may include: ... This is usually the first line of treatment for adenocarcinoma. The goal of surgery is to remove cancer and some of the surrounding tissue. ... This treatment involves using drugs to kill cancer cells. [13] Chemotherapy (chemo) uses anti-cancer drugs that are injected into a vein (through an IV line or central venous catheter) or given by mouth as pills.These drugs enter the bloodstream and reach all areas of the body, making this treatment useful for cancer that has spread to organs beyond where it started.

Differential Diagnosis

Additional Information

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A stomach carcinoma that derives_from epithelial cells of glandular origin.
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