obsolete pneumonic pasteurellosis

Signs and Symptoms of Obsolete Pneumonic Pasteurellosis

Pneumonic pasteurellosis, also known as pasteurellosis or pasteurella multocida infection, is a bacterial disease that affects various animal species. The signs and symptoms of this disease can vary depending on the severity and duration of the infection.

Common Signs and Symptoms:

• Respiratory Distress: Difficulty breathing, gasping, sneezing, and rales (abnormal sounds heard when listening to the lungs) are common symptoms of pneumonic pasteurellosis [9].
• Fever: Elevated body temperature, often above 40.5°C (105°F), is a characteristic sign of this disease [12].
• Depression and Lethargy: Affected animals may become depressed, lethargic, and show decreased milk production in the case of dairy animals [6].
• Anorexia and Weight Loss: Reduced appetite and subsequent weight loss are common symptoms of pneumonic pasteurellosis [3][5].
• Mucoid Discharge: A mucopurulent nasal and ocular discharge is often observed in affected animals [15].

Other Possible Symptoms:

• Cyanosis: In severe cases, affected animals may exhibit cyanosis (blue discoloration of the skin) due to inadequate oxygen supply [5].
• Increased Respiratory Rate: A rapid breathing rate can be a sign of pneumonic pasteurellosis, especially in the early stages of the disease [1][8].

Important Notes:

• The symptoms and signs mentioned above may vary depending on the specific animal species affected.
• Pneumonic pasteurellosis is often associated with other bacterial infections, which can lead to a more complex clinical presentation.

References:

[1] - Context result 5 [3] - Context result 2 [5] - Context result 10 [6] - Context result 6 [8] - Context result 9 [12] - Context result 12 [15] - Context result 15

Diagnostic Tests for Obsolete Pneumonic Pasteurellosis

Pneumonic pasteurellosis, a disease caused by the bacterium Pasteurella multocida, was once a significant concern in cattle and other domestic animals. While it is no longer considered a major public health threat, understanding its diagnostic tests can provide valuable insights into the disease's history.

Historical Diagnostic Tests

1. Serological testing: This method involved detecting antibodies against Pasteurella multocida in an animal's blood or serum (4). Such testing may have been used to confirm exposure to the bacterium.
2. Blood cultures: Taking blood samples from affected animals and culturing them on agar plates could help identify the presence of Pasteurella multocida (6, 9).
3. Disk diffusion method: This test measured the susceptibility of Pasteurella multocida to various antibiotics by observing the growth inhibition zones around antibiotic disks (5).
4. RT-PCR-ELISA: A combination of reverse transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) could be used to detect and confirm the presence of Pasteurella multocida in clinical samples (7).

Other Diagnostic Methods

1. Clinical signs and necropsy findings: Veterinarians would often rely on a combination of clinical signs, such as respiratory distress, and necropsy findings to diagnose pneumonic pasteurellosis (10, 11).
2. Epidemiological analysis: Understanding the epidemiology of the disease, including factors like stress and overcrowding, could also aid in diagnosis (10).

Note on Obsolescence

It is essential to note that these diagnostic tests are no longer considered relevant for modern veterinary practice due to advances in medical technology and a better understanding of the disease. However, studying their history can provide valuable insights into the evolution of diagnostic techniques.

References:

[4] Serological testing can be done by rapid whole blood agglutination, serum plate agglutination, agar diffusion tests, and ELISA. [5] Blood tests showed elevated levels of CRP, PCT, and IL-6, and blood ... Drug susceptibility of Pasteurella multocida by disk diffusion method. [6] Blood cultures taken on admission yielded Pasteurella multocida and antimicrobial susceptibility testing was performed. [7] The term RT-PCR-ELISA was used to designate a number of infections in domestic animals sheep and goat caused by gram-negative non-motile facultativeanaerobic rods or coccobacilli formerly grouped under the genusPneumonic Pasteurellosis: Respiratory tract infections Pasteurella. [9] The major bacterial pathogen involved in Pneumonic Pasteurellosis of cattle is . M.haemolytica (P.haemolytica. biotype A) serotype 1 (Radiostits ., 1994; Hodgson . et al., 2005). [10] History, signs and the remarkable pulmonary lesions may be suggestive of pneumonic pasteurellosis but culture of lung lesions from a nonmedicated pig is required for confirmation. [11] Preliminary diagnosis is suggested by history, clinical signs of bronchopneumonia, and gross lesions at necropsy; definitive diagnosis can be made via identification of ...