plantar verrucous skin carcinoma

Treatment Options for Plantar Verrucous Carcinoma

Plantar verrucous carcinoma, a rare and locally aggressive form of squamous cell carcinoma, can be challenging to treat. While surgical excision is often the primary treatment approach, various drug treatments have been explored to manage this condition.

• Topical Treatments: Topical agents such as salicylic acid are sometimes used as a first-line approach to treating plantar warts, which can be a precursor to verrucous carcinoma. Salicylic acid works by dissolving the protein that holds the keratin cells together, helping to remove the wart.
  • [6] Topical treatment with salicylic acid is often regarded as a first-line approach to treating plantar warts. Salicylic acid is a keratolytic agent and works by ...
• Imiquimod: Imiquimod 5% cream has been used in the treatment of verrucous carcinoma, particularly for its ability to stimulate the immune system and promote the production of interferon-alpha, which can help fight cancer cells.
  • [3] by PC Schalock · 2006 · Cited by 19 — The deep aspect of the tumor had a bulbous, pushing border consistent with the diagnosis of VC. Imiquimod 5% cream was started once daily applied under ...
• Bleomycin: Bleomycin has been used in combination with electrical pulses to enhance its efficacy in treating verrucous carcinoma.
  • [4] by P Pasquali · 2017 · Cited by 24 — Several studies have demonstrated that the efficacy of bleomycin can be greatly improved by coupling its injection with electrical pulses enabling the cells to ...
• Aminolevulinic Acid: Aminolevulinic acid has been used in the treatment of verrucous carcinoma, particularly for its ability to stimulate the production of porphyrins, which can help destroy cancer cells.
  • [7] by E MULHEM · 2011 · Cited by 118 — Aminolevulinic acid is usually applied to the wart for three to eight hours, after which the area is exposed to a range of light sources.

Important Considerations

While these drug treatments may offer some benefits in managing plantar verrucous carcinoma, it's essential to note that surgical excision remains the primary treatment approach. Delaying treatment can give the cancer a chance to spread or worsen, making it more challenging to treat.

Consult with a qualified healthcare professional for personalized advice and guidance on treating plantar verrucous carcinoma.