protein C deficiency

Signs and Symptoms of Protein C Deficiency

Protein C deficiency can manifest in different ways, depending on its severity. Here are some possible signs and symptoms:

• Mild form: Individuals with mild protein C deficiency may be at risk for blood clots in their veins (venous thromboembolism), which can occur in the legs (deep vein thrombosis) or other areas such as the brain, intestines, or arms [1].
• Severe cases: Severe protein C deficiency is a genetic condition that can cause excessive blood clotting and may be characterized by conditions known as disseminated intravascular coagulation (DIC) and purpura fulminans in newborns shortly after birth [13][14].

In some individuals, protein C deficiency may not cause any noticeable symptoms or clotting problems. However, if left untreated, severe cases can lead to serious complications.

Common signs and symptoms of protein C deficiency include:

• Blood clots in the veins (venous thromboembolism)
• Deep vein thrombosis
• Clots in other areas such as the brain, intestines, or arms
• Disseminated intravascular coagulation (DIC)
• Purpura fulminans

It's essential to note that protein C deficiency can be inherited or acquired, and its severity can vary greatly from person to person.

References:

[1] Protein C deficiency is a disorder that increases the risk of developing abnormal blood clots; the condition can be mild or severe. Individuals with mild protein C deficiency are at risk of a type of blood clot known as a deep vein thrombosis (DVT) [2].

[13] Severe protein C deficiency is a genetic condition that will show itself in newborns shortly after they are born. It’s primarily characterized by conditions known as disseminated intravascular coagulation (DIC), which is a condition that affects the blood’s ability to clot, and purpura fulminans [13].

[14] Signs and Symptoms of Protein C Deficiency. Severe protein C deficiency is a genetic condition that will show itself in newborns shortly after they are born. It’s primarily characterized by conditions known as disseminated intravascular coagulation (DIC), which is a condition that affects the blood’s ability to clot, and purpura fulminans [14].