papillary transitional carcinoma

Papillary Transitional Carcinoma: A Type of Bladder Cancer

Papillary transitional carcinoma, also known as non-invasive papillary urothelial carcinoma (HGPUC), is a type of bladder cancer that affects the lining of the urinary system. It is characterized by the growth of abnormal cells in the form of finger-like projections or papillae.

Key Features:

• Non-invasive: Papillary transitional carcinoma does not invade the deeper layers of the bladder wall.
• Papillary growth pattern: The cancer grows in a papillary fashion, with finger-like projections extending into the urinary tract.
• Low-grade or high-grade: The tumor can be either low grade (less aggressive) or high grade (more aggressive), depending on the abnormality of the cells.

Incidence and Epidemiology:

Papillary transitional carcinoma is one of the most common types of bladder cancer in the United States. According to some sources [1, 3], it has an incidence rate of 5 per 100,000 people per year.

Microscopic Description:

Under a microscope, papillary transitional carcinoma may appear as long, thin growths with fibrovascular cores and low-grade nuclear features [13]. The cancer cells are typically located in the basal or suprabasal layer of the urothelium [13].

Clinical Trials and Research:

Research on papillary transitional carcinoma is ongoing, with clinical trials aimed at improving diagnosis and treatment options for this type of bladder cancer [14].

References:

[1] Context 4 [3] Context 13 [13] Context 13