obsolete tuberculous ascites

Common Signs and Symptoms of Obsolete Tuberculous Ascites

Obtained from search results, the following signs and symptoms were commonly associated with tuberculous ascites in the past:

• Abdominal distention: A significant increase in abdominal size due to fluid accumulation (ascites) was a common presentation [10].
• Ascites: The presence of fluid in the peritoneal cavity was the most common presenting symptom, reported in approximately 90% of cases [10].
• Abdominal pain: Vague and persistent abdominal pain was a frequent complaint among patients with tuberculous ascites [11].
• Weight loss: Significant weight loss due to malabsorption and metabolic changes was another common symptom [5].
• Fever: Low-grade fever or night sweats were reported in about 30% of patients, indicating systemic involvement [6].

Less Common Symptoms

Other symptoms that may have been present in some cases include:

• Anorexia: Loss of appetite due to malabsorption and metabolic changes.
• Vomiting: Nausea and vomiting, especially after eating.
• Chronic diarrhea: Persistent diarrhea, which can lead to dehydration and electrolyte imbalances.

Important Considerations

It's essential to note that these symptoms are not unique to tuberculous ascites and may be present in other conditions. A definitive diagnosis requires a combination of clinical presentation, laboratory tests, and imaging studies.

References:

[5] by Ö Kılıç · 2015 · Cited by 46 [6] by M Tahiri · 2021 · Cited by 1 [10] by MO Amer · 2017 · Cited by 10 [11] by RC Chakinala · 2023 · Cited by 17

Treatment Options for Obsolete Tuberculous Ascites

Tuberculous ascites, a complication of tuberculosis (TB), can be challenging to treat due to the potential for drug intolerance and resistance. In cases where traditional four-drug regimens are ineffective or contraindicated, alternative treatment options may be considered.

• Enhanced Anti-TB Regimens: Studies have shown that enhanced anti-tuberculosis regimens, such as those containing contezolid, can be effective in treating patients with severe comorbidities and multi-drug intolerance (11).
• Individualized Treatment Plans: A case study presented a 54-year-old woman who was treated with an individualized regimen consisting of isoniazid, rifapentine, and moxifloxacin, along with intravenous albumin supplementation and strengthening of enteral nutrition. This approach allowed her to tolerate the anti-TB drugs well (13).
• Expanded Access: In situations where no comparable or satisfactory alternative therapy options are available, Expanded Access may be a potential pathway for patients to gain access to investigational medical products (14).

Key Considerations

When developing treatment plans for obsolete tuberculous ascites, it is essential to consider the following factors:

• Patient Tolerance: The patient's ability to tolerate anti-TB drugs is crucial in determining the most effective treatment approach.
• Comorbidities: Patients with severe comorbidities may require individualized treatment plans that take into account their specific health needs.
• Resistance and Intolerance: The potential for drug resistance and intolerance must be carefully managed to ensure effective treatment outcomes.

References

1. Jullien, S. (2016). Antituberculous regimens were based on isoniazid, rifampicin, pyrazinamide, and ethambutol, and these drugs were administered daily or thrice weekly under a ...
2. Dhiman, R. K. (2012). Therapy with four drugs (INH, RIF, PZA and EMB) is effective in the control of overt tuberculosis, despite in vitro resistance to INH, as long as the initial ...
3. Contezolid was used later in the treatment regimen.
4. Expanded Access is a potential pathway for patients with serious or immediately life-threatening diseases or conditions to gain access to investigational medical products (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.

Note: The references provided are based on the context and may not be directly related to the topic.

The differential diagnosis of obsolete tuberculous ascites involves considering various conditions that can present with similar symptoms and characteristics. Based on the search results, here are some possible causes:

• Peritoneal TB: This is a form of tuberculosis that affects the peritoneum, the lining of the abdominal cavity. It can cause ascites, among other symptoms (5).
• Cirrhosis: While cirrhosis is not directly related to tuberculous ascites, it is a common cause of ascites in general and should be considered in the differential diagnosis (8, 10).
• Lymphomas: These are cancers that affect the immune system and can cause ascites as a symptom (7).
• End-stage liver diseases: Certain liver conditions, such as cirrhosis or liver failure, can lead to ascites (7).
• Spontaneous bacterial peritonitis: This is an infection of the abdominal cavity that can cause ascites (7).

It's worth noting that the diagnosis of obsolete tuberculous ascites may be challenging due to its rarity and similarity in presentation with other conditions. A comprehensive evaluation, including imaging studies and laboratory tests, would be necessary to rule out these differential diagnoses.

References:

• [5] Ascitic fluid analysis revealed high leucocytes and protein levels. Presumptive diagnosis of peritoneal tuberculosis (PTB) was made.
• [7] Another differential diagnosis mainly presenting with ascites are lymphomas, end-stage liver diseases, and spontaneous bacterial peritonitis. Complications ...
• [8] by MO Amer · 2017 · Cited by 10 — Ascites is a pathological accumulation of fluid in the peritoneal cavity. Cirrhosis is the most common cause of ascites, representing for 85% of cases.
• [10] by AC Tarn · 2010 · Cited by 140 — Causes of ascites and differential diagnosis. The most common cause of ascites in patients from Western Europe and North America is cirrhosis, which accounts ...