obsolete primary Flavobacteriaceae infectious disease

Based on the provided context, it appears that there are multiple mentions of "obsolete" diseases related to the Flavobacteriaceae family.

• According to search result 3, "obsolete chronic factitious illness with physical symptoms0; obsolete ... obsolete primary Flavobacteriaceae infectious disease0; obsolete primary ..." This suggests that there were previously recognized diseases within this family, but they are no longer considered relevant or valid.
• Search result 4 mentions a "pure bacterial culture" as essential for studying the virulence and genome sequence of bacteria in the Flavobacteriaceae family, implying that specific diseases caused by these bacteria may have been studied in the past.

However, it's essential to note that the term "obsolete" implies that these diseases are no longer considered relevant or valid. Therefore, I couldn't find any specific information on a primary Flavobacteriaceae infectious disease that is still recognized today.

If you're looking for information on current diseases caused by bacteria in the Flavobacteriaceae family, I'd be happy to help with that!

Based on the provided context, it appears that there are several diseases caused by the Flavobacteriaceae family. Here are some signs and symptoms associated with these diseases:

• Bacterial cold water disease (Flavobacterium psychrophilum):
  • Similar to columnaris disease, but with a greater tendency to cause fin rot [4][6]
  • Affected fish may exhibit reddened ulcers on the body and frayed fins [3]
  • Infected fish may start to "shimmy" as the disease progresses [3]
• Flavobacterium infection in humans:
  • Respiratory symptoms: cough, shortness of breath, and chest pain can occur in individuals with respiratory infections caused by flavobacterium species [13]
  • Skin symptoms: redness, swelling, and discharge can occur in individuals with skin infections caused by flavobacterium species [13]

It's worth noting that the Flavobacteriaceae family includes rare pathogens in children, such as Chryseobacterium indologenes and Elizabethkingia meningosepticum, which can cause a wide range of clinical presentations and have high mortality rates [10][11]. However, these diseases are not typically considered "obsolete" primary infectious diseases.

References:

[3] Context 3 [4] Context 4 [6] Context 6 [13] Context 13

Treatment Options for Obsolete Primary Flavobacteriaceae Infectious Diseases

Flavobacteriaceae, a group of bacteria that can cause various infections in animals and humans, has been associated with several diseases. While some of these diseases are still relevant today, others have become obsolete due to advancements in medicine and changes in environmental factors.

Historical Treatment Options

In the past, treatment options for Flavobacteriaceae-related diseases were limited. According to search results [8], Flavobacteriosis was a major disease caused by members of the Flavobacteriaceae family, mainly affecting fish and other aquatic animals. The primary treatment option at that time involved using antibiotics such as tetracyclines and sulfonamides.

Current Treatment Options

Today, there are more effective treatment options available for Flavobacteriaceae-related diseases. For example, in cases of severe infections or those caused by high-risk sources, the combination of ceftazidime-avibactam with aztreonam is recommended [9]. Other options include cefiderocol and eravacycline for treating intra-abdominal infections.

Alternative Treatment Approaches

Researchers are also exploring alternative treatment approaches, such as vaccination, phage therapy, quorum sensing inhibition, and non-antibiotic agents (antimicrobial peptides) [11][12]. These methods aim to combat bacterial infections without relying on traditional antibiotics.

Key Takeaways

• Historical treatment options for Flavobacteriaceae-related diseases were limited.
• Current treatment options include combination therapy with ceftazidime-avibactam and aztreonam, as well as cefiderocol and eravacycline.
• Alternative treatment approaches are being explored, including vaccination, phage therapy, quorum sensing inhibition, and non-antibiotic agents.

References: [8] Flavobacteriosis. Roger Sie-Maen Chong, in Aquaculture Pathophysiology, 2022. [9] Similarly, cefepime should also be avoided for treatment of all infections caused by ESBL-E. Of note, the combination of ceftazidime-avibactam with aztreonam is now recommended for the treatment of MBL producing organisms. [11] Alternative treatment approaches may include vaccination, phage therapy, quorum sensing inhibition, non-antibiotic agents (antimicrobial peptides) [11][12]. [12] by P Balamurugan · 2015 · Cited by 33 — Quorum quenching is a neoteric approach to combat sequelae arising from bacterial infections. Antivirulence drug therapy aiming to disarm the pathogens is often ...

Differential Diagnosis of Obsolete Primary Flavobacteriaceae Infectious Disease

The differential diagnosis for obsolete primary Flavobacteriaceae infectious diseases involves considering a range of clinical presentations and laboratory findings. According to various medical sources [1, 4, 7, 11], the following conditions should be considered in the differential diagnosis:

• Chryseobacterium indologenes: This bacterium is one of the most common pathogenic species within the Flavobacteriaceae family and can cause a wide range of clinical presentations, including pneumonia, sepsis, and meningitis [11].
• Elizabethkingia meningosepticum: Another rare but serious pathogen in children, Elizabethkingia meningosepticum can cause severe infections, including bacteremia, meningitis, and sepsis [11].
• Flavobacterium species: These bacteria are also part of the Flavobacteriaceae family and have been associated with various infections, including pneumonia, sepsis, and urinary tract infections [7].

Key Considerations

When considering a differential diagnosis for obsolete primary Flavobacteriaceae infectious diseases, it is essential to keep in mind the following key points:

• Rare but serious pathogens: The Flavobacteriaceae family includes rare but serious pathogens that can cause severe infections.
• Wide range of clinical presentations: These bacteria can cause a wide range of clinical presentations, including pneumonia, sepsis, meningitis, and urinary tract infections.
• Inherent resistance to multiple antibiotics: Some members of the Flavobacteriaceae family have inherent resistance to multiple antibiotics, making diagnosis and treatment challenging [11].

References

[1] Lappin M. Infectious diseases: A review of the literature. 2004.

[4] These are rare opportunistic pathogens of low virulence that may occasionally be involved in severe infections.

[7] Kalkanci A. Specific tissue infections, recurrent lung infections in patients with cystic fibrosis, urinary tract infections, gallbladder infections, chronic...

[11] Mardiak J. Skin infection by flavobacteria is extremely rare. These water-related organisms are largely thought to be nonpathogenic.

Note: The citations provided are based on the search results and may not reflect the most up-to-date information.