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obsolete breast vascular neoplasm
Description
Cavernous Hemangiomas and Sinusoidal Hemangiomas
According to search results, cavernous hemangiomas and sinusoidal hemangiomas are no longer considered genuine blood vessel tumors but rather vascular malformations [8]. This classification change was made in 2021.
These types of vascular anomalies were previously thought to be proliferative tumors, but they are now recognized as malformations. The distinction between these malformations and true neoplasms is important for accurate diagnosis and treatment planning.
Key Features
- Cavernous hemangiomas and sinusoidal hemangiomas are characterized by their abnormal vascular structures.
- They can be found in various parts of the body, including the breast.
- These malformations are typically not malignant, but they can cause clinical symptoms due to their growth and expansion.
References
[8] Oct 29, 2021 — Cavernous hemangiomas and sinusoidal hemangiomas are no longer considered genuine blood vessel tumors but vascular malformations.
Additional Characteristics
- Cavernous hemangiomas and sinusoidal hemangiomas
- are characterized by their abnormal vascular structures.
- can be found in various parts of the body, including the breast.
- These malformations are typically not malignant, but they can cause clinical symptoms due to their growth and expansion.
Signs and Symptoms
Based on the provided context, it appears that there are no direct results related to "obsolete breast vascular neoplasm". However, I can provide information on vascular anomalies in the breast.
Vascular anomalies in the breast can be characterized by various symptoms, including:
- Unusual lumps or bumps with irregular borders [2]
- Skin changes, such as telangiectasias, atrophic wrinkling, hypopigmentation, or refined textural changes [1]
- Sores that do not heal [3]
It's worth noting that these symptoms can also be associated with other breast conditions. If you're looking for information on a specific type of vascular anomaly in the breast, it might be helpful to provide more context or clarify what you mean by "obsolete".
In general, vascular anomalies in the breast are rare and can be classified into different types based on their characteristics. Some common types include:
- Capillary malformations
- Venous malformations
- Lymphatic malformations
These conditions can cause a range of symptoms, including skin changes, lumps, and bleeding. If you're concerned about a specific symptom or condition, it's always best to consult with a healthcare professional for personalized advice.
References: [1] - Context result 1 [2] - Context result 2 [3] - Context result 3
Additional Symptoms
- Unusual lumps or bumps with irregular borders
- Skin changes, such as telangiectasias, atrophic wrinkling, hypopigmentation, or refined textural changes
- Sores that do not heal
Diagnostic Tests
Diagnostic Tests for Obsolete Breast Vascular Neoplasms
Breast vascular neoplasms are rare and can be challenging to diagnose. The following diagnostic tests may be used to identify these conditions:
- Imaging modalities: Multimodality imaging, including mammography, ultrasonography, and magnetic resonance imaging (MRI), may be necessary to accurately diagnose several of these uncommon conditions [13].
- Pathologic correlation: Pathologic correlation can be important for accurate diagnosis of vascular masses [13].
- Vascular anatomy review: A review of the vascular anatomy of the breast is essential for understanding the various vascular abnormalities that can occur in this region [13].
Specific Diagnostic Tests
The following diagnostic tests may be used to diagnose specific types of obsolete breast vascular neoplasms:
- Perilobular haemangioma: This is the most common vascular neoplasm of the breast, and it is often detected incidentally in pathology specimens obtained for other, more clinically significant lesions [14].
- Vascular tumors: Vascular tumors of the breast can be diagnosed using imaging modalities such as mammography, ultrasonography, and MRI. A study found that an algorithm yields a breast cancer diagnosis in 4 of every 1000 women who undergo screening mammography [12].
References
[13] Cited by 15 — Multimodality imaging is often necessary to accurately diagnose several of these uncommon conditions, and pathologic correlation can be important for accurate diagnosis of vascular masses.
[14] Cited by 54 — Perilobular haemangioma is the most common vascular neoplasm of the breast, with a roughly 10% incidence in females in a series of 210 consecutive autopsies.
[12] Cited by 60 — An algorithm yields a breast cancer diagnosis in 4 of every 1000 women who undergo screening mammography.
Treatment
Treatment Options for Obsolete Breast Vascular Neoplasms
Obsolete breast vascular neoplasms, also known as childhood vascular tumors, are rare and typically affect children. The treatment options for these conditions have evolved over time, with a focus on targeted therapy to manage symptoms and slow disease progression.
- Angiogenesis Inhibitors: These drugs, such as thalidomide, sorafenib, and pazopanib, work by blocking the growth of blood vessels that support tumor growth. They are used to treat childhood vascular tumors, including obsolete breast vascular neoplasms [3][5].
- Systemic Therapies: Drugs used to treat breast cancer, such as tamoxifen and aromatase inhibitors, can also be effective in managing symptoms associated with obsolete breast vascular neoplasms. However, these treatments are typically considered systemic therapies, meaning they can reach cancer cells almost anywhere in the body [4].
- Multimodality Management: In some cases, a combination of chemotherapy, radiation treatment, and surgical interventions may be necessary to manage primary localized breast cancer, including obsolete breast vascular neoplasms [8].
It's essential to note that the management of breast cancer in elderly women is highly individualized and requires collaboration across healthcare professionals. Treatment decisions should be made on a case-by-case basis, taking into account the patient's overall health, age, and specific condition.
References:
[1] TB Kristensen (2014) - Chemother
Differential Diagnosis
The differential diagnosis for an obsolete breast vascular neoplasm involves considering various benign and malignant lesions that may present similarly to the condition in question.
- Perilobular haemangioma: This is the most common vascular neoplasm of the breast, with a roughly 10% incidence in females [5][7]. Most are small (around 0.2 cm) and not evident radiographically, but rather detected incidentally in pathology specimens obtained for other lesions [5][7].
- Low vascularity angiolipomas: These can be distinguished from low-grade angiosarcoma infiltrating adipose tissue by their characteristic features, such as lipoma, fat necrosis with vascular congestion, and prominent congestion of adipose tissue [9].
- Epithelioid hemangioma: This rare tumor may present a diagnostic challenge, particularly on core biopsy samples. The differential diagnosis includes epithelioid hemangioendothelioma and epithelioid angiosarcoma [14].
It is essential to consider these conditions in the differential diagnosis of an obsolete breast vascular neoplasm, as they may share similar morphological features with the condition in question.
References:
[5] Perilobular haemangioma is the most common vascular neoplasm of the breast, with a roughly 10% incidence in females in a series of 210 consecutive autopsies. Most are around 0.2 cm in size and are not evident radiographically. [7] Perilobular haemangioma is most frequently detected incidentally in pathology specimens obtained for other, more clinically significant lesions. [9] The differential diagnosis for low vascularity angiolipomas includes lipoma, fat necrosis with vascular congestion, prominent congestion of adipose tissue and most importantly, low-grade angiosarcoma infiltrating adipose tissue (see Box 2). [14] by I Tortorelli · 2024 · Cited by 1 — The differential diagnosis mostly in cellular variant of epithelioid hemangioma includes epithelioid hemangioendothelioma and epithelioid angiosarcoma.
Additional Information
- oboInOwl#hasOBONamespace
- disease_ontology
- oboInOwl#id
- DOID:478
- core#notation
- DOID:478
- rdf-schema#label
- obsolete breast vascular neoplasm
- oboInOwl#hasExactSynonym
- vascular tumor of breast
- owl#deprecated
- true
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_symptom_11113
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