central nervous system leiomyoma

Central Nervous System Leiomyoma: A Rare Benign Tumor

Central Nervous System (CNS) leiomyoma is a rare type of benign tumor that arises from the smooth muscle cells in the CNS. It is characterized by the presence of intersecting fascicles composed of spindle cells that often lack mitotic activity [1][4].

Definition and Classification

According to the World Health Organization (WHO), CNS leiomyoma is classified as a mesenchymal non-meningothelial brain tumor [12]. It is also known as central nervous system leiomyoma or CNS leiomyoma.

Key Features

• Benign smooth muscle neoplasm arising from the CNS
• Presence of intersecting fascicles composed of spindle cells that often lack mitotic activity [1][4]
• Rare and unusual type of tumor in the CNS

Synonyms

CNS leiomyoma is also referred to as central nervous system leiomyoma, CNS leiomyoma, or leiomyoma of the CNS.

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Diagnostic Tests for Central Nervous System Leiomyoma

Central nervous system (CNS) leiomyomas, also known as angioleiomyomas, are rare benign tumors that arise from smooth muscle cells in the brain or spinal cord. Diagnosing CNS leiomyomas can be challenging due to their rarity and nonspecific symptoms. Here are some diagnostic tests that may be used to diagnose CNS leiomyoma:

• Imaging studies: Imaging tests such as MRI (Magnetic Resonance Imaging) scans, CT (Computed Tomography) scans, and ultrasound may be used to visualize the tumor and its location in the brain or spinal cord [5][11].
• Biopsy: A biopsy, which involves taking a sample of tissue from the tumor, may be performed to confirm the diagnosis. This can be done using imaging guidance such as CT-guided needle core biopsy [9].
• Histopathological examination: The biopsy sample is then examined under a microscope by a pathologist to confirm the presence of smooth muscle cells and rule out other types of tumors [8][9].

It's worth noting that diagnosing CNS leiomyomas can be complex and may require a combination of imaging studies, biopsy, and histopathological examination. A multidisciplinary team of healthcare professionals, including neurologists, radiologists, and pathologists, may be involved in the diagnostic process.

References:

[5] - Ultrasound is used to diagnose the presence and monitor the growth of fibroids: uncomplicated leiomyomas are usually hypoechoic [5]. [8] - A CT-guided needle core biopsy was performed to establish a diagnosis. On microscopy, the specimen was notable for the proliferation of smooth muscle cells [9]. [11] - Angioleiomyoma (ALM), also called angiomyoma or vascular leiomyoma, is defined as a benign and indolent soft tissue neoplasm arising from smooth muscle cells [11].