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basaloid squamous cell carcinoma

Description

Signs and Symptoms

Basaloid squamous cell carcinoma (BSCC) is a rare type of skin cancer that can be challenging to diagnose due to its unique characteristics. While it shares some similarities with other types of skin cancers, BSCC has distinct signs and symptoms that can help identify it.

Common Signs and Symptoms:

  • A slowly growing, non-healing spot on the skin [8]
  • A small, smooth, shiny, or pale growth on the skin [7]
  • An open sore that does not heal, and may bleed, ooze or crust [10]
  • A pinkish growth or a patch of scaly skin [11]

Other Possible Signs:

  • Rough, reddish scaly area [12]
  • Open sore (often with a raised border) [12]
  • Brown spot that looks like an age spot [12]

It's essential to note that BSCC can appear in various ways and may be mistaken for other skin conditions. If you notice any unusual growths or changes on your skin, it's crucial to consult a dermatologist for proper evaluation and diagnosis.

Important: Basaloid squamous cell carcinoma is a type of skin cancer that requires prompt attention. Early detection and treatment can significantly improve outcomes.

References:

[7] - The first sign of basal cell carcinoma is an unusual growth on your skin. [8] - Most basal cell carcinoma's grow slowly. [10] - Frequently, two or more of these warning signs and symptoms are apparent in a BCC tumor. [11] - A common sign of BCC is a small sore that never seems to heal. [12] - You may see any of the following on your skin: Rough, reddish scaly area. Open sore (often with a raised border) Brown spot that looks like an age spot

Additional Symptoms

  • An open sore that does not heal, and may bleed, ooze or crust
  • A slowly growing, non-healing spot on the skin
  • A small, smooth, shiny, or pale growth on the skin
  • A pinkish growth or a patch of scaly skin
  • Rough, reddish scaly area
  • Open sore (often with a raised border)
  • Brown spot that looks like an age spot

Diagnostic Tests

Treatment

Treatment Options for Basaloid Squamous Cell Carcinoma (BSCC)

Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma, primarily found in the head and neck region. While treatment options are limited, research has shown that certain drug treatments can be effective in managing this condition.

  • Targeted Drug Therapy: Targeted drug therapy focuses on specific weaknesses present within cancer cells. In cases of locally advanced, recurrent, or metastatic BSCC, anti-PD1 cemiplimab is recommended as a therapeutic approach (Source: [11]). This treatment option has shown promise in patients who have exhausted other treatment options.
  • Other Treatment Options: While surgery and Mohs micrographic surgery are often considered the optimal treatment options for basal cell carcinoma, BSCC can also be treated successfully with destructive techniques such as curettage alone, cryosurgery, or electrodesiccation (Source: [12]). Additionally, photodynamic therapy, topical drugs like 5-fluorouracil, imiquimod, or ingenol mebutate may be used to treat BSCC.

Important Considerations

It's essential to note that treatment options for BSCC depend on various factors, including the stage of cancer, location, and overall health. Patients should consult with their healthcare provider to determine the best course of treatment for their specific condition.

Sources: [11] In cases of locally advanced, recurrent, or metastatic SCC where options for locoregional treatment are limited, the recommended therapeutic approach is the use of anti-PD1 cemiplimab, especially in patients who have exhausted other treatment options. ... Basaloid squamous cell carcinoma (BSC), a contentious entity within nonmelanoma skin ... [12] Although surgery and Mohs micrographic surgery are often considered the optimal treatment options for basal cell carcinoma, these tumors can also be treated successfully with destructive techniques (eg, curettage alone, cryosurgery, or electrodesiccation), photodynamic therapy, topical drugs (eg, 5-fluorouracil, imiquimod, or ingenol mebutate ...

Differential Diagnosis

Additional Information

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basaloid squamous cell carcinoma
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A squamous cell carcinoma that has a solid, closely packed growth of cells with hyperchromatic nuclei, scant cytoplasm, small cystic spaces, and foci of necrosis. It has overlying squamous dysplasia, rare foci of overt keratinization, and/or coexistent keratinizing squamous cell carcinoma.
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It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.