malignant acrospiroma

Malignant Acrospiroma: A Rare and Aggressive Tumor

Malignant acrospiroma, also known as nodular hidradenocarcinoma, is a rare and aggressive tumor of the eccrine sweat glands. It is characterized by slow-growing nodules that may drain or ulcerate, with sizes ranging from 0.5 to 10 cm [1].

Key Features:

• Aggressive behavior: Malignant acrospiromas are known to be highly aggressive and can recur locally in up to 50% of patients, with distant metastases occurring in some cases [5].
• Rare occurrence: This type of tumor is extremely rare, making it challenging for diagnosis and treatment.
• Slow growth: Lesions manifest as slow-growing nodules that may drain or ulcerate.

Diagnosis and Treatment:

A definitive diagnosis of malignant acrospiroma can be established through excision and histopathological examination. The 5-year survival rate may be as low as [3].

References:

• [1] Lesions manifest as slow growing 0.5 to 10 cm nodules that may drain or ulcerate.
• [2] Malignant acrospiroma is a rare tumor of the eccrine sweat glands that usually displays an aggressive behavior.
• [3] Excision and skin grafting were done and a diagnosis of malignant acrospiroma was established. These tumors are aggressive and 5-year survival rate may be as low as...
• [4] Acrospiromas are a broad class of benign cutaneous adnexal tumors.
• [5] A case of malignant acrospiroma of the hand is reported. This rare sweat gland carcinoma recurs locally in 50% of patients, with distant metastases occurring in some cases.
• [6] Malignant acrospiroma represents a group of benign ductal tumors of the eccrine sweat glands that sometimes are connected to the skin, ranging from solitary plaques to...

Malignant acrospiroma, also known as nodular hidradenocarcinoma, typically presents as large ulcerated nodules on the skin. These nodules can be hard and asymptomatic, or they may cause symptoms such as:

• Ulceration: The nodules can become ulcerated, leading to open sores on the skin.
• Swelling: The affected area may become swollen, red, and inflamed.
• Pain: Some people may experience pain or tenderness in the affected area.

It's worth noting that diagnosis of malignant acrospiroma can be challenging due to its overlap with benign counterparts. A biopsy is often necessary to confirm the diagnosis.

According to [1], patients are monitored for some time before tumors cause symptoms that prompt medical attention. The main clinical manifestations of hidradenocarcinoma, which includes malignant acrospiroma, are isolated, hard, asymptomatic intradermal erythematous, or violaceous nodules on the head, neck, trunk [11].

In rare cases, malignant acrospiroma can spread to nearby tissues, especially lymph nodes, or to more distant parts of the body. This can lead to additional symptoms such as:

• Swollen lymph nodes
• Loss of appetite
• Weight loss

It's essential to seek medical attention if you notice any unusual growths or changes on your skin.

References: [1] - Malignant acrospiroma is a rare tumor of the eccrine sweat glands accounting for around 6% of all malignant eccrine tumors. Typically, it presents as large ulcerated nodules, and diagnosis can be challenging as it has great overlap with its benign counterpart. [11] - The main clinical manifestations of hidradenocarcinoma are isolated, hard, asymptomatic intradermal erythematous, or violaceous nodules on the head, neck, trunk.