seminal vesicle cystadenoma

Seminal Vesicle Cystadenoma: A Rare Benign Tumor

Seminal vesicle cystadenoma is a rare and benign tumor that affects the seminal vesicles, which are small glands located near the prostate gland in men. This type of tumor is characterized by the formation of cysts of varying sizes lined by bland cuboidal epithelium [12].

Macroscopic and Histological Features

Macroscopically, the mass appears as a large oval and brown tissue with multiple cystic loculations [2]. Histologically, the tumor consists of variably sized cysts lined by bland cuboidal cells, which is a characteristic feature of this type of tumor [3].

Clinical Presentation

The clinical presentation of seminal vesicle cystadenoma can vary, but it often includes symptoms such as abdominal pain, perineal pain during ejaculation and defecation, dysuria, and hematuria [13]. These symptoms occur due to the growth of the tumor, which may cause compression or obstruction of surrounding structures.

Diagnosis and Treatment

The diagnosis of seminal vesicle cystadenoma is made on final pathology after surgical resection [11]. Surgical resection is the only curative treatment for this type of tumor. Due to its rarity, there are limited reports of cases in the literature, with only 22 cases noted till now [11].

Classification and Rarity

Seminal vesicle cystadenoma is classified as a rare benign epithelial tumor that arises from the remnants of the Mullerian duct [12]. It is an exceedingly rare condition, with only a few reported cases in the English literature.

References:

[1] Apr 10, 2021 — Seminal vesicle cystadenomas are a benign subgroup of mixed epithelial and stromal tumors of the seminal vesicles. [2] by M Al Barajraji · 2024 — Macroscopically, the mass appeared as a large oval and brown tissue with multiple cystic loculations. [3] Mar 27, 2023 — Cystadenoma is a rare, benign epithelial tumor composed of variably sized cysts lined by bland cuboidal cells; centered in the seminal ... [12] by QZ Tang · 2019 · Cited by 4 — Symptoms or tumor growth occur because the tumor of the seminal vesicle may be malignant or it may grow and become more difficult to excise. [11] by DY Baschinsky · 1998 · Cited by 60 — Resection of the mass yielded a biphasic tumor characterized by cystically dilated glandular spaces admixed with spindle-shaped stromal cells. There was no ... [13] by RA Franca · 2023 · Cited by 1 — Primary seminal vesicle cystadenoma, which frequently involves middle-aged and elderly men, is a benign tumor originating from the embryological residues of the mullerian ducts. [14] The involvement of the seminal vesicle by prostatic adenocarcinoma is by far the commonest malignancy involving the seminal vesicle. 2, 3 The reported examples of primary malignant tumors include adenocarcinoma, squamous cell carcinoma, and sarcoma. Benign primary tumors of seminal vesicle, such as cystadenoma, are even rarer than these ...

Clinical Presentation of Seminal Vesicle Cystadenoma

Seminal vesicle cystadenoma, a rare benign tumor, can manifest with various symptoms. The clinical presentation of this condition is crucial for early diagnosis and treatment.

• Voiding difficulties or hematuria: These are common symptoms reported in patients with seminal vesicle cystadenomas [1][2].
• Hematospermia: This symptom, characterized by the presence of blood in semen, can also be associated with this condition [3].
• Lower urinary tract syndrome: Patients may experience symptoms such as dysuria (painful urination), increased urinary frequency, and painful ejaculation [4].
• Abdominal pain: Perineal pain during ejaculation and defecation, abdominal pain, and rarely hemospermia can also be present in some cases [5].

Diagnosis

The diagnosis of seminal vesicle cystadenoma is primarily based on clinical presentation, imaging studies (e.g., ultrasound), and histopathological examination.

• Imaging studies: Ultrasound and other imaging modalities may help identify the tumor and its location.
• Histopathology: A definitive diagnosis can be made through histopathological examination of tissue samples obtained during biopsy or surgical excision [6].

References

[1] Apr 10, 2021 — Clinical presentation​​ Voiding difficulties or hematuria have been reported as clinical symptoms of seminal vesicle cystadenomas.

[2] by QZ Tang · 2019 · Cited by 4 — Majority of patients present symptoms of hematuria, dysuria, hemastospermia, lower urinary tract syndrome, increased urinary frequency, painful ...

[3] by YX Niu · 2018 · Cited by 2 — [2] Clinical symptoms of primary seminal vesicle include abdominal pain, perineal pain during ejaculation and defecation, dysuria, hematuria, rarely hemospermia ...

[4] by M Al Barajraji · 2024 — While SV tumors can remain asymptomatic and discovered incidentally, they typically manifest with persistent hematuria, hematospermia, or voiding difficulties [...

[5] Mar 27, 2023 — Cystadenoma is a rare, benign epithelial tumor composed of variably sized cysts lined by bland cuboidal cells; centered in the seminal ...

[6] Voiding difficulties or hematuria have been reported as clinical symptoms of seminal vesicle cystadenomas 1,2. Diagnosis. The diagnosis of seminal vesicle ...