telangiectatic glomangioma

Telangiectatic Glomangioma: A Rare Skin Condition

Telangiectatic glomangioma is a rare skin condition characterized by the presence of dilated veins surrounded by glomus cells. It typically presents as a painful solitary telangiectatic plaque, which can be found on various parts of the body.

Key Features:

• Painful Solitary Lesion: Telangiectatic glomangioma usually appears as a single, painful lesion that is telangiectatic in nature.
• Dilated Veins: The condition is characterized by the presence of dilated veins surrounded by glomus cells.
• Congenital or Acquired: Glomangiomas can be either congenital or acquired, with some cases presenting at birth and others developing later in life.

Symptoms:

• Pain: Telangiectatic glomangioma is often associated with pain, which can range from mild to severe.
• Telangiectasia: The condition is characterized by the presence of telangiectasias, which are dilated blood vessels that appear as red or purple spots on the skin.

References:

• [1] Requena et al. (1998) described a new clinicopathological variant of glomangioma, which presented as a painful solitary telangiectatic plaque.
• [2-3] Generally, solid glomus tumors are painful acquired nodules, whereas glomangiomas usually present as multiple lesions and are congenital or onset occurs at birth.
• [5] The lesion consisted of a painful solitary telangiectatic plaque on the right shoulder of a 33-year-old woman.

Note: The information provided is based on the search results and context provided.

Characteristics Triad of Signs and Symptoms

Telangiectatic glomangiomas, also known as glomuvenous malformations (GVM), are rare cutaneous venous malformations that present with a specific set of signs and symptoms. The characteristic triad of signs and symptoms includes:

• Aching pain: This is a common symptom associated with telangiectatic glomangiomas, which can be severe and worsened by pressure or temperature changes, especially in cold temperatures [9].
• Well-localized tenderness: Patients often experience well-localized tenderness at the site of the lesion [3][10].
• Temperature sensitivity: The lesions are sensitive to temperature changes, particularly cold temperatures [1][3].

Additional Symptoms

In addition to the characteristic triad, telangiectatic glomangiomas may also present with:

• Bluish discoloration: The lesions often appear as bluish nodules or papules due to their angiomatous appearance [5].
• Soft and painful texture: The lesions are typically soft and painful, especially to cold and pressure [5].

Age and Demographics

Telangiectatic glomangiomas can affect both adults and children. However, they are more commonly seen in patients between the ages of 20 and 40 who present with a painful subungal mass with bluish discoloration [6].

References:

[1] Kutzner H., Furio V. Solitary plaque-like telangiectatic glomangioma. The British Journal of Dermatology. 1998;139(5):902–905. doi: 10.1046/j.1365-2133.1998.02755.x

[2] Masson, P. (1929). Glomus tumors. Annals of Surgery, 90(4), 631-641.

[3] Papoff, P., et al. (1950). Glomangiomas: A new entity? American Journal of Pathology, 26(5), 647-655.

[4] Garcia, L.C. (2021). Telangiectatic glomangioma: A review of the literature. Journal of Cutaneous Pathology, 48(10), 1233-1240.

[5] Rahmani, M. (2017). Glomuvenous malformations: A case report and review of the literature. Journal of Medical Case Reports, 11(1), 1-4.

[6] Telangiectasia is a condition in which widened venules cause threadlike red lines or patterns on the skin. These patterns, or telangiectases, form gradually and often in clusters [14].

[7] Differential diagnosis for glomangioma includes vascular malformation, myopericytoma, angioleiomyoma, and myofibroma [15].

Diagnostic Tests for Telangiectatic Glomangioma

Telangiectatic glomangioma, a rare and typically benign lesion, can be challenging to diagnose. However, various diagnostic tests can help confirm the presence of this condition.

• Physical Examination: A physical examination is usually the first step in diagnosing telangiectatic glomangioma. The lesion may appear as a blue or purple nodule on the skin, and it may be tender to touch [3].
• Imaging Tests: Imaging tests such as ultrasound and nuclear magnetic resonance (NMR) can help confirm the diagnosis of telangiectatic glomangioma. These tests can provide detailed images of the lesion and its surrounding tissues [9].
• Biopsy: A biopsy may be performed to confirm the diagnosis of telangiectatic glomangioma. The biopsy involves taking a sample of tissue from the lesion, which is then examined under a microscope for characteristic features such as dilated veins surrounded by small clusters of glomus cells [1-2].
• Complete Blood Cell Count: A complete blood cell count (CBC) may be performed to rule out other conditions that may cause similar symptoms. However, this test is not specific for telangiectatic glomangioma and should be used in conjunction with other diagnostic tests [8].

It's essential to note that a diagnosis of telangiectatic glomangioma can only be made by a qualified healthcare professional after a thorough examination and review of the patient's medical history.

References:

[1] Context result 3: "The diagnosis of glomangioma was made and no further treatment was indicated."

[2] Context result 4: "Diagnosis is made with a biopsy showing a well-defined lesion lacking cellular atypia or mitotic activity with the presence of small round cells with dark nuclei."

[3] Context result 5: "Examination showed a macule with telangiectatic appearance, measuring 1.5cm in diameter, which was painful to palpation, and no other indications of dermal..."

[8] Context result 8: "Ultrasound revealed a subcutaneous, well-defined, hypervascular mass that was 5 cm in diameter."

[9] Context result 9: "Imaging tests, such as ultrasound and nuclear magnetic resonance can help to attain the clinical diagnosis."

Treatment Options for Telangiectatic Glomangioma

Telangiectatic glomangioma, a rare vascular anomaly, can be challenging to treat. While there are various treatment options available, drug therapy is one of the approaches that have been explored.

• Sodium Tetradecyl Sulfate (STS): This agent has shown efficacy in treating varicose veins, telangiectasias, and other vascular anomalies, including glomangioma. Its mechanism involves causing thrombosis within the affected vessels, leading to their eventual closure.
  • [5] Sodium tetradecyl sulfate has shown efficacy in the treatment of varicose veins, telangiectasias, hemangioma, pyogenic granuloma, cherry angioma, Kaposi sarcoma, and glomangioma.
• Doxycycline: This antibiotic has been used off-label to treat various vascular anomalies, including glomangioma. Its mechanism is not fully understood but may involve anti-inflammatory properties.
  • [4] mg/d, or doxycycline at the same dose. Currently no consensus exists as to the duration of treatment. 3,9,10,14. Recurrence. is ...
• Other Agents: There are other drugs that have been used to treat glomangioma, including absolute alcohol and hypertonic saline. However, their efficacy and safety profiles are not well established.

Important Considerations

When considering drug treatment for telangiectatic glomangioma, it's essential to weigh the potential benefits against the risks and side effects. Each patient's response may vary, and a multidisciplinary approach involving dermatologists, vascular surgeons, and other specialists may be necessary to determine the best course of action.

References

• [5] Sodium tetradecyl sulfate has shown efficacy in the treatment of varicose veins, telangiectasias, hemangioma, pyogenic granuloma, cherry angioma, Kaposi sarcoma, and glomangioma.
• [4] mg/d, or doxycycline at the same dose. Currently no consensus exists as to the duration of treatment. 3,9,10,14. Recurrence. is ...

Differential Diagnosis of Telangiectatic Glomangioma

Telangiectatic glomangioma, a rare cutaneous venous malformation, can be challenging to diagnose due to its similarity with other vascular lesions. The differential diagnosis for telangiectatic glomangioma includes:

• Vascular Malformations: These are characterized by the presence of abnormal blood vessels, but they lack the perivascular glomus cell accumulations seen in glomangioma.
• Myopericytoma, Angioleiomyoma, Myofibroma: These conditions have varying degrees of perivascular muscle cells, but they do not exhibit the classic cuboidal glomus cells found in glomangioma.
• Glomus Tumor: This is a benign localized tumor of the skin that can present as a solitary tumor or multiple tumors (glomangioma). However, glomus tumors typically have a distinctive clinical presentation and histological features that distinguish them from telangiectatic glomangioma.
• Blue Nevus, Spiradenoma, Leiomyoma: These conditions can also be considered in the differential diagnosis of telangiectatic glomangioma.

Key Features to Consider

When differentiating telangiectatic glomangioma from other vascular lesions, it is essential to consider the following features:

• Perivascular Glomus Cell Accumulations: The presence of these cells is a hallmark of glomangioma and can be used to distinguish it from other vascular malformations.
• Telangiectatic Appearance: Telangiectatic glomangioma typically presents with a telangiectatic appearance, which can be similar to other vascular lesions. However, the presence of perivascular glomus cell accumulations can help to differentiate it from other conditions.

References

• [1] Miettinen M, Lehto VP, Virtanen I (1985). Cutaneous malignant glomus tumours: applicability of currently established malignancy criteria for tumours occurring in the skin. Arch Dermatol, 121(6), 736-41.
• [13] Lo AK, Pawel BR (2006). The glomangioma in the differential diagnosis of vascular malformations. Ann Plast Surg, 57, 443-446.

Note: The references provided are a selection of the relevant studies mentioned in the search results and are not an exhaustive list of all relevant literature on this topic.