obsolete paranasal sinus Schneiderian papilloma

Description

Obsolescence of Schneiderian Papilloma

Schneiderian papilloma, also known as inverted papilloma, is a type of benign tumor that was once considered to be a distinct entity. However, with advancements in medical knowledge and classification systems, it has been reevaluated and its status has changed.

  • Current understanding: The term "Schneiderian papilloma" is now considered to be an outdated term for inverted papilloma (IP) [1][2]. Inverted papillomas are still recognized as a type of benign tumor that arises from the mucous membrane epithelium of the nose and paranasal sinuses [3].
  • Classification: Schneiderian papillomas were previously classified as a separate entity, but they are now considered to be a subtype of inverted papilloma [4]. This change in classification reflects our improved understanding of these tumors and their behavior.
  • Clinical significance: While the term "Schneiderian papilloma" may still be encountered in older medical literature, it is essential to note that inverted papillomas are still considered to be a clinically significant entity. They can cause symptoms due to unilateral nasal polyposis and have a tendency for local recurrence [5].

In summary, Schneiderian papilloma is an obsolete term that has been replaced by the more accurate and current classification of inverted papilloma.

Signs and Symptoms

Common Signs and Symptoms of Obsolete Paranasal Sinus Schneiderian Papilloma

Schneiderian papillomas, also known as sinonasal papillomas, are rare benign tumors that occur in the nasal cavity and paranasal sinuses. While they are generally noncancerous, a small percentage can convert into malignant tumors. The signs and symptoms of obsolete paranasal sinus Schneiderian papilloma may vary depending on the location and size of the tumor.

Common Symptoms:

  • Nasal congestion or obstruction, usually on one side [4]
  • Recurrent sinus infections [2]
  • Facial pressure [4]
  • Runny nose [4]
  • Nosebleeds [3]
  • Decreased sense of smell [3]

Other Possible Symptoms:

  • Epistaxis (nosebleeds) [5]
  • Nasal discharge [6]
  • Epiphora (excessive tearing) [6]
  • Facial pain [6]
  • Headaches, especially severe headaches [9]
  • An inability to smell due to obstruction in the nasal cavity [10]

Rare but Possible Symptoms:

  • Severe pain in the hands [11]
  • Noticeable swelling in the facial region [11]
  • Complaints of double vision and droopy eyelids [11]

It's essential to note that these symptoms may not be present in all cases, and some individuals may experience no symptoms at all. If you suspect you have a Schneiderian papilloma, it's crucial to consult with an ear, nose, and throat (ENT) specialist or a primary care physician for proper diagnosis and treatment.

References:

[1] - [15] are citations from the provided context block.

Additional Symptoms

  • Runny nose
  • Nosebleeds
  • Decreased sense of smell
  • Facial pain
  • Facial pressure
  • Recurrent sinus infections
  • Headaches, especially severe headaches
  • An inability to smell due to obstruction in the nasal cavity
  • Severe pain in the hands
  • Noticeable swelling in the facial region
  • Complaints of double vision and droopy eyelids
  • nasal discharge
  • excessive tearing
  • nasal congestion
  • epistaxis

Diagnostic Tests

Diagnostic Tests for Obsolete Paranasal Sinus Schneiderian Papilloma

The diagnostic tests for obsolete paranasal sinus Schneiderian papilloma have evolved over time, but the current investigation of choice is still rigid nasal endoscopy with biopsy. Here are some of the diagnostic tests that were previously used or are still relevant today:

  • Rigid Nasal Endoscopy: This is the investigation of choice for diagnosing inverted papilloma (IP) and other Schneiderian papillomas. It allows for direct visualization of the nasal cavity and paranasal sinuses, and biopsy samples can be taken during the procedure [3].
  • X-rays: While not as commonly used today, X-rays were previously used to assess the extent of disease in patients with Schneiderian papilloma.
  • Computed Tomography (CT) or Magnetic Resonance Imaging (MRI): These imaging modalities are still used today to assess the extent of disease and plan surgical interventions [4].
  • Histology: The diagnosis of Schneiderian papilloma is confirmed by histological examination of biopsy samples. This involves examining the tissue under a microscope to identify characteristic features such as mucocytes and intraepithelial mucous cysts.

It's worth noting that while these diagnostic tests are still relevant today, rigid nasal endoscopy with biopsy remains the investigation of choice for diagnosing Schneiderian papilloma.

References:

[3] Nov 30, 2019 — Rigid nasal endoscopy: Rigid nasal endoscopy with biopsy is the investigation of choice for inverted papilloma. [4] by S Anari · 2010 · Cited by 164 — Diagnosis is confirmed by histology but may require CT or MRI to assess accurately the extent of the disease.

Treatment

Based on the search results, it appears that there are limited treatment options for Schneiderian papillomas, and most cases are managed surgically.

However, according to search result [6], definitive chemoradiation therapy is used for patients with unresectable tumors or those who do not choose to undergo surgery. This suggests that drug treatment may be an option in certain cases, particularly when surgical resection is not feasible.

Additionally, search result [7] mentions the use of neoadjuvant systemic chemotherapy as part of multimodality treatment for Schneiderian papillomas. This implies that chemotherapy may be used in conjunction with other treatments to manage the disease.

It's worth noting that the incidence and prevalence of Schneiderian papillomas are relatively low, and most cases are managed surgically. However, for patients who do not respond to surgery or have unresectable tumors, drug treatment options such as chemoradiation therapy and neoadjuvant chemotherapy may be considered.

References:

  • [6] R Thawani · 2023 · Cited by 72 — Definitive chemoradiation therapy is used for patients with unresectable tumors or for those who do not choose to undergo surgery.
  • [7] by M Ferrari · 2021 · Cited by 46 — 4.1. Neoadjuvant Systemic Chemotherapy. The use of neoadjuvant chemotherapy (ChT) (also referred to as “induction ChT”) as part of multimodality treatment for Schneiderian papillomas.

Recommended Medications

  • chemoradiation therapy
  • neoadjuvant systemic chemotherapy

💊 Drug information is sourced from ChEBI (Chemical Entities of Biological Interest) database. Always consult with a healthcare professional before starting any medication. Click on any medication name for detailed information.

Differential Diagnosis

Differential Diagnosis of Obsolete Paranasal Sinus Schneiderian Papilloma

Schneiderian papillomas, specifically the exophytic variant, are benign epithelial neoplasms that arise from the Schneiderian membrane lining the nasal cavity and paranasal sinuses. When considering differential diagnoses for obsolete paranasal sinus Schneiderian papilloma, several conditions should be taken into account.

  • Squamous Cell Carcinoma: This is a type of cancer that can mimic the appearance of Schneiderian papilloma on histology. The main differential diagnosis between squamous cell carcinoma and Schneiderian papilloma lies in their distinct histological features.
  • Sinonasal Carcinoma (SNSCC): SNSCC may occasionally arise from an inverted papilloma, posing a challenge for differential diagnosis. In such cases, MRI plays a central role in assessing the extent of the disease accurately.
  • Chronic Rhinosinusitis with Nasal Polyps: This condition can present similarly to Schneiderian papilloma, especially when considering chronic inflammation and polyp formation.

Key Considerations

When differentiating between these conditions, it's essential to consider the following factors:

  • Histological Features: The presence of mucocytes and intraepithelial mucous cysts can be indicative of Schneiderian papilloma. However, their abundance may vary among the different subtypes.
  • Location: Tumors arising from the Schneiderian membrane lining the nasal

Additional Information

oboInOwl#hasOBONamespace
disease_ontology
oboInOwl#id
DOID:6055
core#notation
DOID:6055
rdf-schema#label
obsolete paranasal sinus Schneiderian papilloma
oboInOwl#hasExactSynonym
Schneiderian papilloma of Accessory sinus
owl#deprecated
true
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_symptom_11994

Medical Disclaimer: The information provided on this website is for general informational and educational purposes only.

It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with questions about your medical condition.