nalidixic acid
CHEBI:CHEBI_100147
Definition
A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species.
Chemical Information
- Molecular Formula
- C12H12N2O3
- Molecular Mass
- 232.23530
- Charge
- 0
- SMILES
- CCn1cc(C(O)=O)c(=O)c2ccc(C)nc12
- InChI
- InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
- InChIKey
- MHWLWQUZZRMNGJ-UHFFFAOYSA-N
Alternative Names
- 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure
- 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
- 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid
- 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
- 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
- 1,4-dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
- 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one
- acide nalidixique
- acido nalidixico
- acidum nalidixicum
- nalidixic acid
- Nalidixic acid
- NALIDIXIC ACID
Treatment Applications
-
interstitial cystitisView Disease →
DOID:13949
-
chronic cystitisView Disease →
DOID:1680
Drug Classification
-
monocarboxylic acidView Class →
CHEBI:25384
-
1,8-naphthyridine derivativeView Class →
CHEBI:73537
-
quinolone antibioticView Class →
CHEBI:86324
-
t92260
-
t92340
-
t93039
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Nalidixic_Acid
- core#notation
- CHEBI:100147
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasDbXref
- Wikipedia:Nalidixic_Acid
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#id
- CHEBI:100147
- core#notation
- CHEBI:100147
- oboInOwl#hasAlternativeId
- CHEBI:7456
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59517
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_62070
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109407
- has_treatment
- http://purl.obolibrary.org/obo/DOID_3412
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect1299
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_62070
- owl#annotatedSource
- t93058
- owl#someValuesFrom
- t258393