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Norfloxacin

CHEBI:CHEBI_100246

Definition

A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Chemical Information

Molecular Formula
C16H18FN3O3
Molecular Mass
319.33080
Charge
0
SMILES
CCn1cc(C(O)=O)c(=O)c2cc(F)c(cc12)N1CCNCC1
InChI
InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChIKey
OGJPXUAPXNRGGI-UHFFFAOYSA-N

Alternative Names

  • 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
  • 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
  • 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
  • 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
  • NFLX
  • norfloxacin
  • norfloxacine
  • norfloxacino
  • norfloxacinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
7517
oboInOwl#hasDbXref
Wikipedia:Norfloxacin
core#notation
CHEBI:100246

Additional References

Wikipedia:Norfloxacin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

DRON_00010000
7517
oboInOwl#hasDbXref
Wikipedia:Norfloxacin
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#id
CHEBI:100246
core#notation
CHEBI:100246
oboInOwl#hasAlternativeId
CHEBI:7629
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59517
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_1076
owl#annotatedSource
t93020
owl#someValuesFrom
t936307