Discuss This Drug

Sumatriptan

CHEBI:CHEBI_10650

Definition

A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Chemical Information

Molecular Formula
C14H21N3O2S
Molecular Mass
295.40000
Charge
0
SMILES
CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
InChI
InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3
InChIKey
KQKPFRSPSRPDEB-UHFFFAOYSA-N

Alternative Names

  • (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
  • 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide
  • 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide
  • 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide
  • 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide
  • Imigran
  • Imitrex
  • Sumatran
  • sumatriptan
  • sumatriptanum
  • Sumax

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
37418
oboInOwl#hasDbXref
Wikipedia:Sumatriptan
core#notation
CHEBI:10650

Additional References

Wikipedia:Sumatriptan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
NASAL
package_ndc
80425-0318-2
spl_id
08918eab-05d3-4d11-b013-4c6ee1835fe7
product_ndc
58437-016
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
37418
oboInOwl#hasDbXref
Wikipedia:Sumatriptan
oboInOwl#id
CHEBI:10650
generic_name
sumatriptan succinate and naproxen sodium
brand_name
Tosymra
brand_name_base
Tosymra
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35941
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_28969
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_64364
package_description
1 mL in 1 VIAL (71205-111-01)
dosage_form
SPRAY
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Tonix Medicines, Inc.
application_number
NDA210884
package_marketing_start_date
02-APR-09
marketing_start_date
20000405
listing_expiration_date
20241231
active_ingredient_strength
5 mg/100uL
active_ingredient_name
SUMATRIPTAN
unii
8R78F6L9VO
spl_set_id
38fd19bf-b7aa-812c-8a74-2414dfec45f4
rxcui
1739337
manufacturer_name
Tonix Medicines, Inc.
core#notation
CHEBI:10650
pharm_class
Serotonin-1b and Serotonin-1d Receptor Agonist [EPC]
pharm_class_moa
Serotonin 1d Receptor Agonists [MoA]
pharm_class_epc
Serotonin-1b and Serotonin-1d Receptor Agonist [EPC]
nui
N0000175765
upc
0372603141016
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109033
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect1577
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64364
owl#annotatedSource
t96766
owl#someValuesFrom
t3038109