Discuss This Drug

Clodronic Acid

CHEBI:CHEBI_110423

Definition

An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases.

Chemical Information

Molecular Formula
CH4Cl2O6P2
Molecular Mass
244.89200
Charge
0
SMILES
OP(O)(=O)C(Cl)(Cl)P(O)(O)=O
InChI
InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9)
InChIKey
ACSIXWWBWUQEHA-UHFFFAOYSA-N

Alternative Names

  • (Dichloro-phosphono-methyl)-phosphonic acid
  • (dichloromethanediyl)bis(phosphonic acid)
  • (dichloromethylene)bisphosphonic acid
  • (dichloromethylene)diphosphonic acid
  • acide clodronique
  • acido clodronico
  • acidum clodronicum
  • clodronate
  • clodronic acid
  • clodronsaeure
  • dichloromethylene-1,1-bisphosphonic acid
  • dichloromethylene-1,1-diphosphonic acid
  • dichloromethylidene diphosphonate

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3350
oboInOwl#hasDbXref
PMID:8421279
core#notation
CHEBI:110423

Additional References

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Additional Attributes

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chebi_ontology
DRON_00010000
3350
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CHEBI:110423
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CHEBI:110423
RO_0000087
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