Discuss This Drug

erlotinib

CHEBI:CHEBI_114785

Definition

A quinazoline compound having a (3-ethynylphenyl)amino group at the 4-position and two 2-methoxyethoxy groups at the 6- and 7-positions.

Chemical Information

Molecular Formula
C22H23N3O4
Molecular Mass
393.43570
Charge
0
SMILES
COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC
InChI
InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)
InChIKey
AAKJLRGGTJKAMG-UHFFFAOYSA-N

Alternative Names

  • [6,7-bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine
  • [6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynylphenyl)amine
  • erlotinib
  • erlotinibum
  • N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:114785
DRON_00010000
337525
oboInOwl#hasDbXref
Wikipedia:Erlotinib

Additional References

Wikipedia:Erlotinib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER, FOR SUSPENSION
marketing_start_date
20120526
labeler_name
Sichuan Xieli Pharmaceutical Co., Ltd.
spl_id
d87de259-bcd3-4295-883e-65eda7dc599a
package_ndc
63592-3400-2
application_number
ANDA091059
product_ndc
59651-531
core#notation
CHEBI:114785
pharm_class_epc
Kinase Inhibitor [EPC]
pharm_class
Protein Kinase Inhibitors [MoA]
pharm_class_moa
Protein Kinase Inhibitors [MoA]
upc
0346708567309
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
1088255
active_ingredient_strength
100 kg/100kg
package_marketing_start_date
26-MAY-12
nui
N0000175076
manufacturer_name
MSN LABORATORIES PRIVATE LIMITED
active_ingredient_name
ERLOTINIB
unii
DA87705X9K
spl_set_id
5d97f401-4853-4a9a-907d-21e8a4d16088
package_description
1 kg in 1 CARTON (63592-3407-2)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
337525
oboInOwl#hasDbXref
Wikipedia:Erlotinib
oboInOwl#id
CHEBI:114785
oboInOwl#hasAlternativeId
CHEBI:40877
generic_name
erlotinib hydrochloride
brand_name
TARCEVA
brand_name_base
TARCEVA
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_74440
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0070552
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect1595
owl#annotatedSource
t96765
owl#someValuesFrom
t965582