Discuss This Drug

pimavanserin

CHEBI:CHEBI_133017

Definition

A member of the class of ureas in which three of the four hydrogens are replaced by 4-fluorobenzyl, 1-methylpiperidin-4-yl, and 4-(isopropyloxy)benzyl groups. An atypical antipsychotic that is used (in the form of its tartrate salt) for treatment of hallucinations and delusions associated with Parkinson's disease.

Chemical Information

Molecular Formula
C25H34FN3O2
Molecular Mass
427.556
Charge
0
SMILES
C1=C(C=CC(=C1)CNC(N(C2CCN(CC2)C)CC3=CC=C(C=C3)F)=O)OCC(C)C
InChI
InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
InChIKey
RKEWSXXUOLRFBX-UHFFFAOYSA-N

Alternative Names

  • N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide
  • N-[(4-fluorophenyl)methyl]-N-(1-methylpiperidin-4-yl)-N'-{[4-(2-methylpropoxy)phenyl]methyl}urea
  • pimavanserin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:133017
DRON_00010000
1791685
oboInOwl#hasDbXref
Wikipedia:Pimavanserin

Additional References

Wikipedia:Pimavanserin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:133017
rxcui
2049278
route
ORAL
active_ingredient_strength
34 mg/1
pharm_class
Atypical Antipsychotic [EPC]
package_marketing_start_date
29-APR-16
active_ingredient_name
PIMAVANSERIN TARTRATE
package_ndc
63090-340-30
package_description
30 CAPSULE in 1 BOTTLE, PLASTIC (63090-340-30)
manufacturer_name
Acadia Pharmaceuticals Inc.
unii
NA83F1SJSR
spl_set_id
1e6bea44-57d6-4bac-9328-46e1ee59f83b
upc
0363090100303
spl_id
99eb5c18-de12-df79-e053-2a95a90a541c
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1791685
oboInOwl#hasDbXref
Wikipedia:Pimavanserin
oboInOwl#id
CHEBI:133017
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
TABLET, COATED
marketing_start_date
20160429
labeler_name
Acadia Pharmaceuticals Inc.
generic_name
pimavanserin tartrate
product_ndc
63090-340
brand_name
NUPLAZID
brand_name_base
NUPLAZID
application_number
NDA210793
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_133016
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_133020
has_treatment
http://purl.obolibrary.org/obo/DOID_10340
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect1966
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_133020
owl#annotatedSource
t100697
owl#someValuesFrom
t3300292