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Nesiritide

CHEBI:CHEBI_135919

Chemical Information

Molecular Formula
C143H244N50O42S4
Molecular Mass
3464.047
Charge
0
SMILES
[H]N[C@@H](CO)C(N1CCC[C@H]1C(N[C@@H](CCCCN)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H](CO)C(NCC(N[C@H]2CSSC[C@H](NC(CNC([C@H](CC(C)C)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)NC([C@@H](NC([C@@H](NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@@H](NC(CNC([C@@H](NC2=O)CC3=CC=CC=C3)=O)=O)CCCNC(N)=N)=O)=O)=O)CC(O)=O)=O)CCCNC(N)=N)=O)=O)CO)=O)CO)=O)CO)=O)CO)=O)=O)=O)=O)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
InChI
InChI=1S/C143H244N50O42S4/c1-13-76(10)112-137(232)189-99(68-199)131(226)188-98(67-198)130(225)187-97(66-197)129(224)186-96(65-196)117(212)166-59-105(202)169-90(52-72(2)3)114(209)163-61-107(204)171-100(132(227)177-83(32-19-22-44-146)124(219)190-111(75(8)9)136(231)184-91(53-73(4)5)127(222)175-84(34-24-46-159-141(151)152)121(216)174-85(35-25-47-160-142(153)154)122(217)185-94(139(234)235)55-78-57-157-71-167-78)69-238-239-70-101(172-108(205)62-165-116(211)95(64-195)170-106(203)60-162-113(208)87(38-39-103(148)200)181-135(230)110(74(6)7)191-126(221)89(41-51-237-12)179-120(215)82(31-18-21-43-145)180-134(229)102-37-27-49-193(102)138(233)79(147)63-194)133(228)182-92(54-77-28-15-14-16-29-77)115(210)164-58-104(201)168-80(33-23-45-158-140(149)150)118(213)173-81(30-17-20-42-144)119(214)178-88(40-50-236-11)123(218)183-93(56-109(206)207)128(223)176-86(125(220)192-112)36-26-48-161-143(155)156/h14-16,28-29,57,71-76,79-102,110-112,194-199H,13,17-27,30-56,58-70,144-147H2,1-12H3,(H2,148,200)(H,157,167)(H,162,208)(H,163,209)(H,164,210)(H,165,211)(H,166,212)(H,168,201)(H,169,202)(H,170,203)(H,171,204)(H,172,205)(H,173,213)(H,174,216)(H,175,222)(H,176,223)(H,177,227)(H,178,214)(H,179,215)(H,180,229)(H,181,230)(H,182,228)(H,183,218)(H,184,231)(H,185,217)(H,186,224)(H,187,225)(H,188,226)(H,189,232)(H,190,219)(H,191,221)(H,192,220)(H,206,207)(H,234,235)(H4,149,150,158)(H4,151,152,159)(H4,153,154,160)(H4,155,156,161)/t76-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,110-,111-,112-/m0/s1
InChIKey
HPNRHPKXQZSDFX-OAQDCNSJSA-N

Alternative Names

  • Brain natriuretic peptide-32
  • Human brain natriuretic factor-32
  • Human brain natriuretic peptide-32
  • Natriuretic peptide type-B
  • nesiritide recombinant

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
19666
oboInOwl#hasDbXref
Drug_Central:1901
core#notation
CHEBI:135919

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
19666
oboInOwl#hasDbXref
Drug_Central:1901
oboInOwl#id
CHEBI:135919
core#notation
CHEBI:135919
generic_name
NESIRITIDE CITRATE
listing_expiration_date
20251231
dosage_form
POWDER
active_ingredient_strength
1 g/g
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
active_ingredient_name
NESIRITIDE
product_ndc
35207-0009
labeler_name
BCN PEPTIDES SA
marketing_start_date
20170901
spl_id
d5739d38-e1f7-a4bc-e053-2995a90ad621
package_ndc
35207-0009-5
package_description
500 g in 1 BOTTLE (35207-0009-5)
package_marketing_start_date
01-SEP-17
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#2_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_105269
owl#annotatedSource
t108766
owl#someValuesFrom
t3000704