ambrisentan

CHEBI:CHEBI_135949

Chemical Information

Molecular Formula
C22H22N2O4
Molecular Mass
378.422
Charge
0
SMILES
C([C@H](OC=1N=C(C)C=C(N1)C)C(O)=O)(OC)(C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1
InChIKey
OUJTZYPIHDYQMC-LJQANCHMSA-N

Alternative Names

  • letairis
  • LU 208075
  • LU208075
  • volibris

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
358274
oboInOwl#hasDbXref
Drug_Central:4337
core#notation
CHEBI:135949

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
358274
generic_name
Ambrisentan
brand_name
Letairis
brand_name_base
Letairis
oboInOwl#hasDbXref
Drug_Central:4337
oboInOwl#id
CHEBI:135949
product_type
BULK INGREDIENT
marketing_category
EXPORT ONLY
listing_expiration_date
20241231
dosage_form
POWDER
labeler_name
Medichem Manufacturing (Malta) Ltd.
marketing_start_date
20100323
product_ndc
69097-387
application_number
ANDA210701
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#2_STAR
route
ORAL
spl_id
fa986fe6-b59e-1b85-c60b-632e2aaf813d
package_ndc
69097-387-19
package_description
1 BLISTER PACK in 1 CARTON (69097-387-19) / 10 TABLET, FILM COATED in 1 BLISTER PACK
core#notation
CHEBI:135949
rxcui
722124
active_ingredient_strength
75 kg/75kg
manufacturer_name
Cipla USA Inc.
package_marketing_start_date
15-JUN-19
pharm_class_epc
Endothelin Receptor Antagonist [EPC]
pharm_class
Endothelin Receptor Antagonists [MoA]
pharm_class_moa
Endothelin Receptor Antagonists [MoA]
active_ingredient_name
AMBRISENTAN
unii
HW6NV07QEC
spl_set_id
0e3e3320-27ac-404f-9f01-3d82696e768a
nui
N0000175364
upc
0382009141305
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_6432
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect4954
owl#annotatedSource
t108686
owl#someValuesFrom
t985705